Trade Name
stringlengths 3
57
⌀ | Generic/Proper Name(s)
stringlengths 4
79
| Active Ingredient(s)
stringlengths 4
64
⌀ | Cardiotoxicity
stringclasses 3
values | DICT Concern
stringclasses 6
values | Keywords
stringlengths 5
112
⌀ | DIC Severity Level
stringclasses 5
values |
|---|---|---|---|---|---|---|
FOTIVDA
|
TIVOZANIB
|
tivozanib hydrochloride
|
Heart Damage
|
most
|
fatal Cardiac Failure
|
severe
|
BALVERSA
|
ERDAFITINIB
|
Erdafitinib
|
Heart Damage
|
less
|
acute myocardial infarction.
|
severe
|
Orladeyo
|
BEROTRALSTAT HYDROCHLORIDE
|
Berotralstat hydrochloride
|
Arrhythmia
|
less
|
QT Prolongation with Higher-Than-Recommended Dosages
|
moderate
|
FARXIGA
|
DAPAGLIFLOZIN
|
DAPAGLIFLOZIN PROPANEDIOL
| null |
no
|
not prolong the QT interval
| null |
Velphoro
|
SUCROFERRIC OXYHYDROXIDE
|
FERRIC OXYHYDROXIDE
| null |
no
| null | null |
Macrilen
|
MACIMORELIN ACETATE
|
MACIMORELIN
|
Arrhythmia
|
most
|
QTc interval prolongation
|
moderate
|
BOSULIF
|
BOSUTINIB MONOHYDRATE
|
BOSUTINIB MONOHYDRATE
|
Heart Damage
|
most
|
cardiac failure
|
severe
|
Rezurock
|
BELUMOSUDIL
|
BELUMOSUDIL
|
Heart Damage
|
less
|
hypertension
|
mild
|
JAKAFI
|
RUXOLITINIB
|
RUXOLITINIB
|
Heart Damage
|
most
|
cardiovascular death/myocardial infarction,
|
severe
|
VERMOX
|
MEBENDAZOLE
|
mebendazole
| null |
no
| null | null |
PARNATE
|
TRANYLCYPROMINE SULFATE
|
TRANYLCYPROMINE SULFATE
|
Heart Damage
|
less
|
Hypertension
|
mild
|
WELIREG
|
BELZUTIFAN
|
BELZUTIFAN
|
Heart Damage
|
less
|
Hypertension
|
mild
|
Trulance Immediate release
|
PLECANATIDE
|
Plecanatide
| null |
no
| null | null |
Xyrem
|
SODIUM OXYBATE
|
SODIUM OXYBATE
| null |
no
| null | null |
Qulipta
|
ATOGEPANT
|
ATOGEPANT
| null |
no
|
not prolong the QTc interval
| null |
Gleostine
|
LOMUSTINE
|
LOMUSTINE
| null |
no
| null | null |
Incruse Ellipta
|
UMECLIDINIUM
|
UMECLIDINIUM BROMIDE
|
Arrhythmia
|
less
|
supraventricular tachycardia
|
moderate
|
Cefditoren Pivoxil
|
CEFDITOREN PIVOXIL
|
CEFDITOREN PIVOXIL
| null |
no
| null | null |
Lysodren
|
MITOTANE
|
mitotane
| null |
no
| null | null |
DIURIL
|
CHLOROTHIAZIDE
|
CHLOROTHIAZIDE
|
Heart Damage
|
less
|
Hypotension
|
mild
|
CRIXIVAN
|
INDINAVIR SULFATE
|
INDINAVIR SULFATE
|
Heart Damage
|
less
|
myocardial infarction
|
severe
|
EVRYSDI
|
RISDIPLAM
|
RISDIPLAM
| null |
no
| null | null |
Reyvow
|
LASMIDITAN
|
lasmiditan
|
Mixed
|
less
|
palpitations/increase blood pressure
|
mild
|
Horizant
|
GABAPENTIN ENACARBIL
|
gabapentin enacarbil
| null |
no
|
not prolong QT interval
| null |
Emcyt
|
ESTRAMUSTINE PHOSPHATE SODIUM
|
ESTRAMUSTINE PHOSPHATE SODIUM
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Nucynta ER
|
TAPENTADOL HYDROCHLORIDE
|
TAPENTADOL HYDROCHLORIDE
|
Heart Damage
|
less
|
hypotension
|
mild
|
CAPLYTA
|
LUMATEPERONE
|
LUMATEPERONE
|
Heart Damage
|
less
|
hypotension
|
mild
|
KOSELUGO
|
SELUMETINIB
|
SELUMETINIB
|
Heart Damage
|
most
|
Cardiomyopathy
|
severe
|
TAZVERIK
|
TAZEMETOSTAT
|
tazemetostat hydrobromide
| null |
no
|
not prolong the QTc interval
| null |
Mulpleta
|
LUSUTROMBOPAG
|
LUSUTROMBOPAG
| null |
no
|
not prolong the QTc interval
| null |
Vascepa
|
ICOSAPENT ETHYL
|
ICOSAPENT ETHYL
|
Arrhythmia
|
less
|
atrial fibrillation/atrial flutter
|
mild
|
Cotellic
|
COBIMETINIB
|
COBIMETINIB FUMARATE
|
Heart Damage
|
most
|
Cardiomyopathy
|
severe
|
MOVANTIK
|
NALOXEGOL OXALATE
|
NALOXEGOL OXALATE
| null |
no
|
not prolong the QTc interval
| null |
Cedax
|
CEFTIBUTEN DIHYDRATE
|
Ceftibuten dihydrate
| null |
no
| null | null |
COPIKTRA
|
DUVELISIB
|
DUVELISIB
| null |
no
|
QTc interval were not observed
| null |
Verzenio
|
ABEMACICLIB
|
abemaciclib
| null |
ambiguous
|
cardiac failure(drug Combination )
|
severe
|
Lithium
|
LITHIUM
|
Lithium Citrate
|
Mixed
|
most
|
myocarditis/prolonged QT interval
|
severe
|
INGREZZA
|
VALBENAZINE
|
VALBENAZINE TOSYLATE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
Xospata
|
GILTERITINIB
|
GILTERITINIB FUMARATE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
PONVORY
|
PONESIMOD
|
Ponesimod
|
Mixed
|
less
|
Atrioventricular Conduction Delays/Increased Blood Pressure
|
mild
|
Orilissa
|
ELAGOLIX
|
ELAGOLIX SODIUM
| null |
no
|
not prolong the QTc interval
| null |
ZOLINZA
|
VORINOSTAT
|
VORINOSTAT
|
Heart Damage
|
less
|
myocardial infarction
|
severe
|
Varubi
|
ROLAPITANT
|
ROLAPITANT HYDROCHLORIDE
| null |
no
|
not prolong the QTc interval
| null |
IMPAVIDO
|
MILTEFOSINE
|
MILTEFOSINE
| null |
no
|
not prolong the QTc interval
| null |
Xalkori
|
CRIZOTINIB
|
CRIZOTINIB
|
Arrhythmia
|
most
|
QT Interval Prolongation
|
moderate
|
Ayvakit
|
AVAPRITINIB
|
avapritinib
|
Heart Damage
|
less
|
cardiac failure
|
severe
|
Vizimpro
|
DACOMITINIB
|
DACOMITINIB
| null |
no
|
no large effect on QTc
| null |
IBSRELA
|
TENAPANOR HYDROCHLORIDE
|
TENAPANOR HYDROCHLORIDE
| null |
no
|
not prolong the QTc interval
| null |
Xofluza
|
BALOXAVIR MARBOXIL
|
BALOXAVIR MARBOXIL
| null |
no
|
not prolong the QTc interval
| null |
Thalomid
|
THALIDOMIDE
|
THALIDOMIDE
|
Mixed
|
most
|
myocardial infarction/Bradycardia
|
severe
|
MOTEGRITY
|
PRUCALOPRIDE
|
PRUCALOPRIDE SUCCINATE
| null |
no
|
not prolong the QTc interval
| null |
PROMACTA
|
ELTROMBOPAG OLAMINE
|
ELTROMBOPAG OLAMINE
| null |
no
|
not prolong the QTc interval
| null |
ERLEADA
|
APALUTAMIDE
|
Apalutamide
|
Heart Damage
|
most
|
ischemic cardiovascular
events
|
severe
|
Lithostat
|
ACETOHYDROXAMIC ACID
|
ACETOHYDROXAMIC ACID
|
Arrhythmia
|
less
|
Palpitations
|
mild
|
Rinvoq
|
UPADACITINIB
|
upadacitinib
|
Heart Damage
|
most
|
sudden cardiovascular death
|
severe
|
Sular
|
NISOLDIPINE
|
NISOLDIPINE
|
Mixed
|
less
|
congestive heart failure/supraventricular
tachycardia
|
severe
|
Mavenclad
|
CLADRIBINE
|
Cladribine
|
Heart Damage
|
most
|
life-threatening acute
cardiac failure
|
severe
|
EGATEN
|
TRICLABENDAZOLE
|
TRICLABENDAZOLE
|
Arrhythmia
|
most
|
prolongation of the mean QTc interval
|
severe
|
Peganone
|
ETHOTOIN
|
ETHOTOIN
| null |
no
| null | null |
NINLARO
|
IXAZOMIB
|
ixazomib citrate
| null |
no
|
not prolong the QTc interval
| null |
Viberzi
|
ELUXADOLINE
|
ELUXADOLINE
| null |
no
|
not prolong the QTc interval
| null |
BAFIERTAM
|
MONOMETHYL FUMARATE
|
monomethyl fumarate
| null |
no
|
not prolong the QTc interval
| null |
Zelnorm
|
TEGASEROD
|
tegaserod
| null |
ambiguous
|
patients has increased risk of developing an adverse cardiovascular event
| null |
ISENTRESS
|
ISENTRESS
|
RALTEGRAVIR POTASSIUM
| null |
no
|
not prolong QT interval
| null |
Ofev
|
NINTEDANIB
|
NINTEDANIB ESYLATE
|
Heart Damage
|
most
|
Myocardial infarction
|
severe
|
Prilosec
|
OMEPRAZOLE MAGNESIUM
|
OMEPRAZOLE MAGNESIUM
|
Mixed
|
less
|
Chest pain or angina/ tachycardia
|
moderate
|
Gilotrif
|
AFATINIB
|
AFATINIB
| null |
no
|
No large changes in the mean QTc interval
| null |
Rubraca
|
RUCAPARIB
|
rucaparib camsylate
|
Mixed
|
less
|
ischemic cardiovascular events
|
severe
|
OXBRYTA
|
VOXELOTOR
|
Voxelotor
| null |
no
|
not prolong QT interval
| null |
ELIQUIS
|
APIXABAN
|
APIXABAN
|
Heart Damage
|
less
|
hypotension
|
mild
|
Tradjenta
|
LINAGLIPTIN
|
LINAGLIPTIN
|
Heart Damage
|
most
|
heart failure
|
severe
|
ZEPOSIA; ZEPOSIA 7-Day Starter Pack; ZEPOSIA Starter Kit
|
OZANIMOD HYDROCHLORIDE
|
OZANIMOD HYDROCHLORIDE
|
Mixed
|
less
|
Atrioventricular Conduction Delays/Increased Blood Pressure
|
mild
|
Cystadane
|
BETAINE
|
BETAINE
| null |
no
| null | null |
RIDAURA
|
AURANOFIN
|
AURANOFIN
| null |
no
| null | null |
TAGRISSO
|
OSIMERTINIB
|
OSIMERTINIB
|
Mixed
|
most
|
cardiomyopathy/QTc Interval Prolongation
|
severe
|
EXKIVITY
|
MOBOCERTINIB
|
Mobocertinib
|
Mixed
|
most
|
life-threatening heart rate-corrected QT (QTc) prolongation/cardiomyopathy
|
severe
|
Darvon-N
|
PROPOXYPHENE NAPSYLATE
|
propoxyphene napsylate
|
Heart Damage
|
less
|
hypotension
|
mild
|
ADDYI
|
FLIBANSERIN
|
Flibanserin
|
Heart Damage
|
less
|
hypotension
|
mild
|
Fetzima
|
LEVOMILNACIPRAN HYDROCHLORIDE
|
LEVOMILNACIPRAN HYDROCHLORIDE; levomilnacipran hydrochloride
|
Mixed
|
less
|
Increased heart rate/Elevated Blood Pressure
|
mild
|
Seysara
|
SARECYCLINE HYDROCHLORIDE
|
SARECYCLINE HYDROCHLORIDE
| null |
ambiguous
|
Intracranial hypertension
| null |
Marplan
|
ISOCARBOXAZID
|
ISOCARBOXAZID
|
Heart Damage
|
less
|
Hypotension
|
mild
|
PREZISTA
|
DARUNAVIR
|
darunavir ethanolate
| null |
no
|
not affect the QT/QTc interval
| null |
SAVAYSA
|
EDOXABAN TOSYLATE
|
EDOXABAN TOSYLATE
| null |
no
|
not affect the QT/QTc interval
| null |
XPOVIO
|
SELINEXOR
|
selinexor
|
Heart Damage
|
less
|
cardiac failure
|
severe
|
Fexinidazole
|
FEXINIDAZOLE
|
FEXINIDAZOLE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
Pretomanid
|
PRETOMANID
|
Pretomanid
| null |
ambiguous
|
QT prolongation with the combination
| null |
Rukobia
|
FOSTEMSAVIR TROMETHAMINE
|
FOSTEMSAVIR TROMETHAMINE
|
Arrhythmia
|
less
|
QTc Prolongation with Higher than Recommended Dosages
|
moderate
|
XURIDEN
|
URIDINE TRIACETATE
|
uridine triacetate
| null |
no
| null | null |
BYLVAY
|
ODEVIXIBAT
|
odevixibat
| null |
no
| null | null |
LUPKYNIS
|
VOCLOSPORIN
|
VOCLOSPORIN
|
Mixed
|
most
|
prolongs the QTc interval/Hypertension
|
moderate
|
DOJOLVI
|
TRIHEPTANOIN
|
TRIHEPTANOIN
| null |
no
| null | null |
Cesamet
|
NABILONE
|
NABILONE
|
Mixed
|
less
|
tachycardia/hypotension
|
mild
|
Rexulti
|
BREXPIPRAZOLE
|
brexpiprazole
|
Heart Damage
|
less
|
Hypotension
|
mild
|
NOURIANZ
|
ISTRADEFYLLINE
|
istradefylline
| null |
no
|
not affect the QT/QTc interval
| null |
FINTEPLA
|
FENFLURAMINE
|
FENFLURAMINE
|
Heart Damage
|
most
|
valvular heart disease
|
severe
|
Recorlev
|
LEVOKETOCONAZOLE
|
LEVOKETOCONAZOLE
|
Arrhythmia
|
most
|
life-threatening ventricular dysrhythmias
|
severe
|
LUMAKRAS
|
SOTORASIB
|
SOTORASIB
|
Mixed
|
less
|
cardiac arrest /cardiac failure
|
severe
|
Nardil
|
PHENELZINE SULFATE
|
PHENELZINE SULFATE
|
Heart Damage
|
less
|
changes in blood pressure
|
mild
|
Arakoda
|
TAFENOQUINE
|
TAFENOQUINE
| null |
ambiguous
|
mean increase in the QTcF interval less than 20 msec.
| null |
ERIVEDGE
|
VISMODEGIB
|
VISMODEGIB
| null |
no
|
not prolong QT interval
| null |
Subsets and Splits
No community queries yet
The top public SQL queries from the community will appear here once available.