Trade Name
stringlengths 3
57
⌀ | Generic/Proper Name(s)
stringlengths 4
79
| Active Ingredient(s)
stringlengths 4
64
⌀ | Cardiotoxicity
stringclasses 3
values | DICT Concern
stringclasses 6
values | Keywords
stringlengths 5
112
⌀ | DIC Severity Level
stringclasses 5
values |
|---|---|---|---|---|---|---|
ZYPITAMAG
|
PITAVASTATIN MAGNESIUM
|
PITAVASTATIN
| null |
no
| null | null |
BREXAFEMME
|
IBREXAFUNGERP
|
IBREXAFUNGERP CITRATE
| null |
no
|
not prolong QTc
| null |
HIPREX
|
METHENAMINE HIPPURATE
|
METHENAMINE HIPPURATE
| null |
no
| null | null |
Tybost
|
COBICISTAT
|
COBICISTAT
| null |
no
| null | null |
VERQUVO
|
VERICIGUAT
|
VERICIGUAT
|
Heart Damage
|
less
|
Hypotension
|
mild
|
Rozlytrek
|
ENTRECTINIB
|
ENTRECTINIB
|
Mixed
|
most
|
congestive heart failure /QT Interval Prolongation
|
severe
|
XIFAXAN
|
RIFAXIMIN
|
RIFAXIMIN
| null |
no
| null | null |
PIZENSY
|
LACTITOL
|
LACTITOL
|
Heart Damage
|
less
|
Increased blood pressure
|
mild
|
Avandia
|
ROSIGLITAZONE MALEATE
|
ROSIGLITAZONE MALEATE
|
Heart Damage
|
most
|
congestive heart failure
|
severe
|
EMFLAZA
|
DEFLAZACORT
|
DEFLAZACORT
|
Heart Damage
|
less
|
elevation of blood pressure
|
mild
|
Ketek
|
TELITHROMYCIN
|
telithromycin
|
Arrhythmia
|
most
|
torsades de pointes
|
severe
|
Daurismo
|
GLASDEGIB
|
GLASDEGIB
|
Arrhythmia
|
most
|
QTc prolongation
|
moderate
|
ORFADIN
|
NITISINONE
|
NITISINONE
| null |
no
| null | null |
ZYKADIA
|
CERITINIB
|
CERITINIB
|
Arrhythmia
|
most
|
QTc interval prolongation
|
moderate
|
Vumerity
|
DIROXIMEL FUMARATE
|
diroximel fumarate
| null |
no
|
not prolong the QTc interval
| null |
Multaq
|
DRONEDARONE
|
Dronedarone
|
Mixed
|
most
|
Class IV heart failure/atrial fibrillatio n
|
severe
|
Cenestin
|
SYNTHETIC CONJUGATED ESTROGENS, A
|
ESTROGENS, CONJUGATED SYNTHETIC A
|
Heart Damage
|
most
|
myocardial infarction and strok
|
severe
|
Quazepam
|
QUAZEPAM
|
QUAZEPAM
| null |
no
| null | null |
Northera
|
DROXIDOPA
|
DROXIDOPA
|
Heart Damage
|
most
|
supine hypertension
|
mild
|
Boniva
|
IBANDRONATE SODIUM
|
IBANDRONATE SODIUM
|
Heart Damage
|
less
|
Hypertension
|
mild
|
Livalo
|
PITAVASTATIN CALCIUM
|
pitavastatin calcium
| null |
no
|
not prolongation of the QTc interval
| null |
Olumiant
|
BARICITINIB
|
baricitinib
|
Heart Damage
|
most
|
sudden cardiovascular death
|
severe
|
Zokinvy
|
LONAFARNIB
|
LONAFARNIB
|
Heart Damage
|
less
|
Hypertension
|
mild
|
ZONTIVITY
|
VORAPAXAR
|
VORAPAXAR SULFATE
| null |
no
|
no effect on the QTc interval
| null |
RYDAPT
|
RYDAPT
|
MIDOSTAURIN
|
Mixed
|
less
|
Cardiac failure/QT prolongation
|
severe
|
CALQUENCE
|
ACALABRUTINIB
|
ACALABRUTINIB
|
Arrhythmia
|
less
|
atrial fibrillation/atrial flutter
|
mild
|
citalopram
|
CITALOPRAM
|
CITALOPRAM HYDROBROMIDE
|
Arrhythmia
|
most
|
QT-Prolongation and Torsade de Pointes
|
severe
|
Alunbrig
|
BRIGATINIB
|
brigatinib
|
Mixed
|
less
|
Bradycardia/Hypertension
|
mild
|
FARYDAK
|
PANOBINOSTAT
|
PANOBINOSTAT LACTATE
|
Mixed
|
most
|
cardiac ischemic events/severe arrhythmias
|
severe
|
ZEJULA
|
NIRAPARIB
|
niraparib
|
Heart Damage
|
less
|
Hypertension
|
mild
|
Jardiance
|
EMPAGLIFLOZIN
|
empagliflozin
| null |
no
| null | null |
Fycompa
|
PERAMPANEL
|
PERAMPANEL
| null |
ambiguous
|
Multiorgan hypersensitivity:myocarditis
| null |
BRILINTA
|
TICAGRELOR
|
TICAGRELOR
|
Arrhythmia
|
most
|
ventricular pauses
|
moderate
|
DOPTELET
|
AVATROMBOPAG MALEATE
|
AVATROMBOPAG MALEATE
| null |
no
|
not prolong the QTc interval
| null |
Ibrance
|
PALBOCICLIB
|
PALBOCICLIB
| null |
no
|
no effect on QTc
| null |
Gilenya
|
FINGOLIMOD HCL
|
FINGOLIMOD HYDROCHLORIDE
|
Mixed
|
most
|
third-degree AV block/Increased Blood Pressure
|
severe
|
TYKERB
|
LAPATINIB
|
LAPATINIB DITOSYLATE
|
Mixed
|
most
|
decrease LVEF/QT Prolongation
|
moderate
|
Cholbam
|
CHOLIC ACID
|
CHOLIC ACID
| null |
no
| null | null |
amiloride hydrocloride
|
AMILORIDE HYDROCLORIDE
|
AMILORIDE HYDROCHLORIDE
|
Mixed
|
less
|
Angina pectoris/Arrhythmia
|
mild
|
VEMLIDY
|
TENOFOVIR ALAFENAMIDE
|
TENOFOVIR ALAFENAMIDE FUMARATE
| null |
no
|
not affect the QT/QTc interval
| null |
UKONIQ
|
UMBRALISIB
|
umbralisib tosylate
| null |
no
| null | null |
TABLOID
|
THIOGUANINE
|
THIOGUANINE
| null |
no
| null | null |
azithromycin
|
AZITHROMYCIN
|
azithromycin
|
Mixed
|
less
|
Arrhythmias/chest pain
|
mild
|
Vraylar
|
CARIPRAZINE
|
CARIPRAZINE
|
Heart Damage
|
less
|
hypotension
|
mild
|
Tasigna
|
NILOTINIB
|
NILOTINIB
|
Arrhythmia
|
most
|
prolongs the QT interval
|
moderate
|
Revlimid
|
LENALIDOMIDE
|
LENALIDOMIDE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Toviaz
|
FESOTERODINE FUMARATE
|
FESOTERODINE FUMARATE
|
Mixed
|
less
|
angina/QT prolongation on ECG
|
severe
|
Lenvima
|
LENVATINIB
|
LENVATINIB
|
Mixed
|
most
|
cardiomyopathy/QT Interval Prolongation
|
severe
|
PURINETHOL
|
MERCAPTOPURINE
|
MERCAPTOPURINE
| null |
no
| null | null |
Aplenzin
|
BUPROPION HYDROBROMIDE
|
BUPROPION HYDROBROMIDE
|
Heart Damage
|
less
|
hypertension
|
mild
|
Chemet
|
SUCCIMER
|
SUCCIMER
|
Arrhythmia
|
less
|
Arrhythmia
|
mild
|
Aemcolo
|
RIFAMYCIN
|
Rifamycin
| null |
no
| null | null |
COMETRIQ
|
CABOZANTINIB
|
cabozantinib s-malate
|
Heart Damage
|
less
|
Hypertension
|
mild
|
Stendra
|
AVANAFIL
|
AVANAFIL
|
Heart Damage
|
less
|
angina
|
moderate
|
Cerdelga
|
ELIGLUSTAT
|
eliglustat
|
Arrhythmia
|
most
|
increases in ECG intervals (PR, QTc, and QRS)
|
moderate
|
Krintafel
|
TAFENOQUINE SUCCINATE
|
TAFENOQUINE SUCCINATE
| null |
no
|
not prolong the QTc interval
| null |
Kerendia
|
FINERENONE
|
FINERENONE
| null |
no
|
not prolong the QTc interval
| null |
ESBRIET
|
PIRFENIDONE
|
PIRFENIDONE
| null |
no
|
no evidence that ESBRIET
prolonged the QTc interval
| null |
LOKELMA
|
SODIUM ZIRCONIUM CYCLOSILICATE
|
SODIUM ZIRCONIUM CYCLOSILICATE
| null |
no
| null | null |
Pomalyst
|
POMALIDOMIDE
|
POMALIDOMIDE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Galafold
|
MIGALASTAT HYDROCHLORIDE
|
MIGALASTAT HYDROCHLORIDE
| null |
no
|
not prolong the QT interval
| null |
DYANAVEL XR; Dyanavel XR
|
AMPHETAMINE
|
AMPHETAMINE
|
Mixed
|
most
|
myocardial infarction/Heart Rate Increases
|
severe
|
Tasmar
|
TOLCAPONE
|
Tolcapone
|
Mixed
|
less
|
heart failure/tachycardia
|
severe
|
RETEVMO
|
SELPERCATINIB
|
selpercatinib
|
Mixed
|
most
|
QT Interval Prolongation/Hypertension
|
moderate
|
XTAMPZA ER
|
OXYCODONE
|
OXYCODONE
|
Heart Damage
|
less
|
hypotension
|
mild
|
INLYTA
|
AXITINIB
|
AXITINIB
|
Heart Damage
|
most
|
cardiac failure
|
severe
|
Thiola EC
|
TIOPRONIN
|
TIOPRONIN
|
Heart Damage
|
less
|
congestive heart failure
|
severe
|
SCEMBLIX
|
ASCIMINIB
|
ASCIMINIB HYDROCHLORIDE
|
Mixed
|
most
|
cardiac failure/QTc prolongation,
|
severe
|
Mekinist
|
TRAMETINIB
|
TRAMETINIB DIMETHYL SULFOXIDE
|
Heart Damage
|
most
|
cardiac failure
|
severe
|
FIBRICOR
|
FENOFIBRIC ACID
|
Fenofibric Acid
| null |
no
| null | null |
KISQALI
|
RIBOCICLIB
|
RIBOCICLIB SUCCINATE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
GOCOVRI
|
AMANTADINE
|
AMANTADINE
|
Heart Damage
|
less
|
hypotension
|
mild
|
Aptiom
|
ESLICARBAZEPINE ACETATE
|
ESLICARBAZEPINE ACETATE
| null |
ambiguous
|
Multiorgan hypersensitivity:myocarditis
| null |
Tafinlar
|
DABRAFENIB
|
DABRAFENIB MESYLATE
|
Heart Damage
|
most
|
cardiomyopathy
|
severe
|
Osphena
|
OSPEMIFENE
|
OSPEMIFENE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Enablex
|
DARIFENACIN
|
DARIFENACIN
|
Arrhythmia
|
less
|
palpitations
|
mild
|
Trimethoprim
|
TRIMETHOPRIM
|
TRIMETHOPRIM
| null |
no
| null | null |
BRUKINSA
|
ZANUBRUTINIB
|
ZANUBRUTINIB
|
Arrhythmia
|
less
|
Atrial fibrillation
|
mild
|
UBRELVY
|
UBROGEPANT
|
UBROGEPANT
| null |
no
|
not prolong the QT interval
| null |
TRUSELTIQ
|
INFIGRATINIB
|
INFIGRATINIB
| null |
no
|
not prolong the QT interval
| null |
Nexavar
|
SORAFENIB
|
SORAFENIB
|
Mixed
|
most
|
cardiac ischemia/infarction/QT Prolongation
|
severe
|
QINLOCK
|
RIPRETINIB
|
Ripretinib
|
Heart Damage
|
most
|
cardiac failure
|
severe
|
Primsol
|
TRIMETHOPRIM HYDROCHLORIDE
|
TRIMETHOPRIM HYDROCHLORIDE
| null |
no
| null | null |
Nerlynx
|
NERATINIB
|
NERATINIB MALEATE
| null |
no
|
not prolong the QT interval
| null |
XARELTO; Xarelto
|
RIVAROXABAN
|
rivaroxaban
| null |
no
| null | null |
Afinitor; Afinitor Disperz
|
EVEROLIMUS
|
EVEROLIMUS
|
Mixed
|
less
|
congestive cardiac failure /Tachycardia
|
severe
|
Viramune
|
NEVIRAPINE
|
NEVIRAPINE
| null |
no
| null | null |
VIRACEPT
|
NELFINAVIR MESYLATE
|
NELFINAVIR MESYLATE
|
Arrhythmia
|
less
|
torsades de pointes
|
moderate
|
Iclusig
|
PONATINIB HYDROCHLORIDE
|
ponatinib hydrochloride
|
Mixed
|
most
|
fatal myocardial infarction/cardiac arrhythmias
|
severe
|
Xenical
|
ORLISTAT
|
ORLISTAT
| null |
no
| null | null |
HYCAMTIN
|
TOPOTECAN
|
TOPOTECAN HYDROCHLORIDE
| null |
no
| null | null |
Xtandi
|
ENZALUTAMIDE
|
ENZALUTAMIDE
|
Heart Damage
|
most
|
ischemic heart disease
|
severe
|
SUNOSI
|
SOLRIAMFETOL
|
SOLRIAMFETOL
|
Mixed
|
less
|
Blood Pressure Heart Rate Increases
|
mild
|
ELMIRON
|
PENTOSAN POLYSULFATE SODIUM
|
PENTOSAN POLYSULFATE SODIUM
| null |
no
| null | null |
PIFELTRO
|
DORAVIRINE
|
doravirine
| null |
no
|
not prolong the QT interval
| null |
Plaquenil
|
HYDROXYCHLOROQUINE SULFATE
|
HYDROXYCHLOROQUINE SULFATE
|
Mixed
|
most
|
Cardiomyopathy/QT prolongation
|
severe
|
BRAFTOVI
|
ENCORAFENIB
|
ENCORAFENIB
|
Arrhythmia
|
most
|
QTc interval prolongation
|
moderate
|
ENJUVIA
|
SYNTHETIC CONJUGATED ESTROGENS, B
|
ESTROGENS, CONJUGATED SYNTHETIC B
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Firdapse
|
AMIFAMPRIDINE PHOSPHATE
|
amifampridine phosphate
|
Heart Damage
|
less
|
Hypertension
|
mild
|
Xermelo
|
TELOTRISTAT ETHYL
|
telotristat ethyl
| null |
no
|
not prolong the QT interval
| null |
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