Trade Name
stringlengths 3
57
⌀ | Generic/Proper Name(s)
stringlengths 4
79
| Active Ingredient(s)
stringlengths 4
64
⌀ | Cardiotoxicity
stringclasses 3
values | DICT Concern
stringclasses 6
values | Keywords
stringlengths 5
112
⌀ | DIC Severity Level
stringclasses 5
values |
|---|---|---|---|---|---|---|
Ravicti
|
GLYCEROL PHENYLBUTYRATE
|
GLYCEROL PHENYLBUTYRATE
| null |
no
|
QTcI) for RAVICTI was below 10 ms
| null |
OPSUMIT
|
MACITENTAN
|
macitentan
|
Heart Damage
|
less
|
hypotension
|
mild
|
ONGLYZA
|
SAXAGLIPTIN
|
saxagliptin hydrochloride
|
Heart Damage
|
most
|
heart failure
|
severe
|
DIFICID; Dificid
|
FIDAXOMICIN
|
FIDAXOMICIN
| null |
no
| null | null |
Wakix
|
PITOLISANT HYDROCHLORIDE
|
PITOLISANT HYDROCHLORIDE
|
Arrhythmia
|
most
|
QT Interval Prolongation
|
moderate
|
Xadago
|
SAFINAMIDE MESYLATE
|
SAFINAMIDE MESYLATE
|
Heart Damage
|
less
|
hypertension
|
mild
|
Turalio
|
PEXIDARTINIB
|
PEXIDARTINIB HYDROCHLORIDE
|
Heart Damage
|
less
|
Hypertension
|
mild
|
CAPRELSA
|
VANDETANIB
|
VANDETANIB
|
Mixed
|
most
|
prolong the QT interval/Heart failure
|
severe
|
Zydelig
|
IDELALISIB
|
IDELALISIB
| null |
no
|
not prolong the QT/QTc interval
| null |
Benznidazole
|
BENZNIDAZOLE
|
BENZNIDAZOLE
| null |
no
| null | null |
Dipentum
|
OLSALAZINE SODIUM
|
OLSALAZINE SODIUM
|
Mixed
|
less
|
myocarditis
|
severe
|
PEMAZYRE
|
PEMIGATINIB
|
PEMIGATINIB
| null |
ambiguous
|
patients with electrocardiogram QT prolonged
| null |
Isturisa
|
OSILODROSTAT
|
OSILODROSTAT PHOSPHATE
|
Arrhythmia
|
most
|
QT interval prolongation
|
moderate
|
Prograf
|
TACROLIMUS
|
anhydrous tacrolimus
|
Heart Damage
|
less
|
Myocardial Hypertrophy
|
mild
|
ONGENTYS
|
OPICAPONE
|
OPICAPONE
|
Heart Damage
|
less
|
hypotension
|
mild
|
Priftin
|
RIFAPENTINE
|
RIFAPENTINE
|
Mixed
|
less
|
tachycardia/pericarditis
|
mild
|
Matulane
|
PROCARBAZINE HYDROCHLORIDE
|
PROCARBAZINE HYDROCHLORIDE
|
Mixed
|
less
|
Hypotension/tachycardia
|
mild
|
Katerzia
|
AMLODIPINE
|
Amlodipine Benzoate
|
Heart Damage
|
most
|
acute myocardial infarction
|
severe
|
FACTIVE
|
GEMIFLOXACIN MESYLATE
|
GEMIFLOXACIN MESYLATE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
Juxtapid
|
LOMITAPIDE MESYLATE
|
LOMITAPIDE MESYLATE
|
Mixed
|
less
|
Angina pectoris/Palpitations
|
moderate
|
Dibenzyline
|
PHENOXYBENZAMINE HYDROCHLORIDE
|
PHENOXYBENZAMINE HYDROCHLORIDE
| null |
ambiguous
|
tachycardia(Drug Interactions)
| null |
NUBEQA
|
DAROLUTAMIDE
|
DAROLUTAMIDE
|
Mixed
|
less
|
cardiac failure/arrest
|
severe
|
Lynparza
|
OLAPARIB
|
OLAPARIB
| null |
no
| null | null |
Sovaldi
|
SOFOSBUVIR
|
SOFOSBUVIR
| null |
ambiguous
|
requiring pacemaker
intervention(Coadministered with Amiodarone)
| null |
Edarbi
|
AZILSARTAN KAMEDOXOMIL
|
Azilsartan kamedoxomil
| null |
ambiguous
|
Hypotens ionin Volume- or Salt-Depleted Patients
| null |
PYtest
|
UREA, C-14
|
Urea C-14
| null |
no
|
not prolong the QT/QTc interval
| null |
Pranactin-Citric
|
UREA C-13
|
UREA C-13
| null |
no
| null | null |
Odomzo
|
SONIDEGIB
|
SONIDEGIB PHOSPHATE
| null |
no
|
not prolong the QT/QTc interval
| null |
TEPMETKO
|
TEPOTINIB HYDROCHLORIDE
|
Tepotinib Hydrochloride
| null |
no
|
not prolong the QT/QTc interval
| null |
Keveyis
|
DICHLORPHENAMIDE
|
DICHLORPHENAMIDE
|
Heart Damage
|
less
|
cardiac failure
|
severe
|
Fanapt
|
ILOPERIDONE
|
ILOPERIDONE
|
Mixed
|
most
|
QTc prolongation/hypotension
|
moderate
|
Agrylin
|
ANAGRELIDE HYDROCHLORIDE
|
ANAGRELIDE HYDROCHLORIDE ANHYDROUS
|
Mixed
|
most
|
increases the QTc interval /Hypertension
|
mild
|
Livmarli
|
MARALIXIBAT CHLORIDE
|
maralixibat chloride
| null |
no
| null | null |
Lucemyra
|
LOFEXIDINE HYDROCHLORIDE
|
LOFEXIDINE HYDROCHLORIDE
|
Mixed
|
most
|
prolongs the QT interval/hypotension
|
severe
|
SYMPROIC
|
NALDEMEDINE
|
naldemedine tosylate
| null |
no
|
not prolong the QT/QTc interval
| null |
Otezla
|
APREMILAST
|
APREMILAST
| null |
no
| null | null |
Invirase
|
SAQUINAVIR MESYLATE
|
SAQUINAVIR MESYLATE
|
Mixed
|
most
|
Torsade de pointes
|
severe
|
Inrebic
|
FEDRATINIB HYDROCHLORIDE
|
FEDRATINIB HYDROCHLORIDE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Idhifa
|
ENASIDENIB MESYLATE
|
ENASIDENIB MESYLATE
|
Heart Damage
|
most
|
pericardial effusion
|
severe
|
VIIBRYD
|
VILAZODONE HYDROCHLORIDE
|
VILAZODONE HYDROCHLORIDE
|
Arrhythmia
|
less
|
Palpitations
|
mild
|
Hepsera
|
ADEFOVIR DIPIVOXIL
|
adefovir dipivoxil
| null |
no
| null | null |
ANZEMET
|
DOLASETRON MESYLATE
|
DOLASETRON MESYLATE
|
Arrhythmia
|
most
|
prolongs the QT interval
|
severe
|
TABRECTA
|
CAPMATINIB
|
CAPMATINIB
| null |
no
|
not prolong the QT/QTc interval
| null |
JANUVIA
|
SITAGLIPTIN
|
SITAGLIPTIN PHOSPHATE
|
Heart Damage
|
most
|
heart failure
|
severe
|
Corlanor
|
IVABRADINE
|
IVABRADINE HYDROCHLORIDE
|
Arrhythmia
|
most
|
heart block
|
moderate
|
Radiogardase
|
PRUSSIAN BLUE INSOLUBLE CAPSULES
|
FERRIC FERROCYANIDE
| null |
no
| null | null |
Trintellix
|
VORTIOXETINE
|
VORTIOXETINE HYDROBROMIDE
| null |
ambiguous
|
QTc was below 10 ms
| null |
TAVALISSE
|
FOSTAMATINIB
|
FOSTAMATINIB
|
Heart Damage
|
most
|
increases the QTc interval /Hypertension
|
mild
|
Alinia
|
NITAZOXANIDE
|
NITAZOXANIDE
| null |
no
| null | null |
Vyvanse
|
LISDEXAMFETAMINE DIMESYLATE
|
LISDEXAMFETAMINE DIMESYLATE
|
Mixed
|
most
|
Sudden death/myocardial infarction/Heart rate
|
severe
|
Hetlioz; Hetlioz LQ
|
TASIMELTEON
|
TASIMELTEON
| null |
no
| null | null |
Pradaxa
|
DABIGATRAN ETEXILATE MESYLATE
|
DABIGATRAN ETEXILATE MESYLATE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
TPOXX
|
TECOVIRIMAT MONOHYDRATE
|
TECOVIRIMAT MONOHYDRATE
| null |
no
|
not prolong the QT/QTc interval
| null |
IRESSA
|
GEFITINIB
|
GEFITINIB
| null |
no
| null | null |
Mycapssa
|
OCTREOTIDE
|
Octreotide
|
Arrhythmia
|
most
|
QT prolongation
|
moderate
|
Orenitram
|
TREPROSTINIL
|
treprostinil
| null |
ambiguous
|
not been evaluated in a
thorough QTc study.
| null |
Ruzurgi
|
AMIFAMPRIDINE
|
Amifampridine
| null |
no
|
not prolong the QTc interval
| null |
Adempas
|
RIOCIGUAT
|
RIOCIGUAT
|
Heart Damage
|
less
|
Hypotension
|
mild
|
MAYZENT
|
SIPONIMOD
|
SIPONIMOD
|
Mixed
|
less
|
atrioventricular conduction delays /Hypertension
|
mild
|
Savella
|
MILNACIPRAN HYDROCHLORIDE
|
MILNACIPRAN HYDROCHLORIDE; milnacipran hydrochloride
|
Mixed
|
less
|
Elevated Heart Rate/Elevated Blood Pressure
|
mild
|
Sapropterin Dihydrochloride
|
SAPROPTERIN DIHYDROCHLORIDE
|
SAPROPTERIN DIHYDROCHLORIDE
|
Heart Damage
|
less
|
myocardial infarction
|
severe
|
BELVIQ XR; Belviq
|
LORCASERIN HYDROCHLORIDE HEMIHYDRATE
|
LORCASERIN HYDROCHLORIDE HEMIHYDRATE
|
Mixed
|
most
|
Regurgitant cardiac valvular disease/Heart Rate Decreases
|
severe
|
SPRYCEL
|
DASATINIB
|
dasatinib
|
Mixed
|
most
|
cardiac ischemic events/QT Prolongation
|
severe
|
SOLOSEC
|
SECNIDAZOLE
|
SECNIDAZOLE
| null |
no
|
no clinically relevant increase in the QTc
| null |
DURLAZA
|
ACETYLSALICYLIC ACID
|
Aspirin
| null |
no
|
reduce the risk of death and myocardial infarction
| null |
Diacomit
|
STIRIPENTOL
|
Stiripentol
| null |
no
| null | null |
PROCYSBI
|
CYSTEAMINE BITARTRATE
|
Cysteamine bitartrate
| null |
ambiguous
|
Benign Intracranial Hypertension
| null |
Auryxia
|
FERRIC CITRATE
|
TETRAFERRIC TRICITRATE DECAHYDRATE
| null |
no
| null | null |
Synthroid
|
LEVOTHYROXINE SODIUM
|
LEVOTHYROXINE
|
Mixed
|
less
|
myocardial infarction/ cardiac arrest
|
severe
|
TIBSOVO
|
IVOSIDENIB
|
ivosidenib
|
Arrhythmia
|
most
|
QT (QTc) prolongation
|
severe
|
MYTESI
|
CROFELEMER
|
CROFELEMER
| null |
no
|
not prolong the QTc interval
| null |
Livtencity
|
MARIBAVIR
|
MARIBAVIR
| null |
no
|
not prolong the QTc interval
| null |
ALECENSA
|
ALECTINIB HYDROCHLORIDE
|
ALECTINIB HYDROCHLORIDE
|
Arrhythmia
|
less
|
bradycardia
|
mild
|
Xcopri; Xcopri Maintenance Pack; Xcopri Titration Pack
|
CENOBAMATE
|
CENOBAMATE
|
Arrhythmia
|
most
|
QT Shortening
|
moderate
|
Cevimeline
|
CEVIMELINE
|
CEVIMELINE HYDROCHLORIDE
|
Mixed
|
less
|
tachycardia, bradycardia/ hypotension, hypertension
|
mild
|
Orgovyx
|
RELUGOLIX
|
RELUGOLIX
|
Arrhythmia
|
most
|
prolong the QT/QTc interval
|
severe
|
Rayaldee
|
CALCIFEDIOL
|
CALCIFEDIOL
|
Heart Damage
|
less
|
congestive heart failure
|
severe
|
Tetracycline Hydrochloride
|
TETRACYCLINE HYDROCHLORIDE
|
TETRACYCLINE HYDROCHLORIDE
| null |
ambiguous
|
Intracranial hypertension
| null |
AUSTEDO; Austedo
|
DEUTETRABENAZINE
|
DEUTETRABENAZINE
|
Arrhythmia
|
most
|
prolong the QT interval
|
severe
|
SIRTURO
|
BEDAQUILINE FUMARATE
|
Bedaquiline Fumarate
|
Arrhythmia
|
most
|
QT Prolongation
|
moderate
|
Lorbrena
|
LORLATINIB
|
LORLATINIB
|
Mixed
|
most
|
3 degree atrioventricular (AV) block/Hypertension
|
severe
|
QELBREE
|
VILOXAZINE HYDROCHLORIDE
|
VILOXAZINE HYDROCHLORIDE
|
Mixed
|
less
|
Increase in Heart Rate or Blood Pressure
|
mild
|
Trecator
|
ETHIONAMIDE
|
ETHIONAMIDE
| null |
no
| null | null |
TAVNEOS
|
AVACOPAN
|
AVACOPAN
|
Heart Damage
|
less
|
Hypertension
| null |
XELJANZ; XELJANZ XR
|
TOFACITINIB
|
TOFACITINIB CITRATE
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Moxidectin
|
MOXIDECTIN
|
MOXIDECTIN
|
Heart Damage
|
less
|
symptomatic orthostatic hypotension
|
mild
|
Desvenlafaxine
|
DESVENLAFAXINE
|
DESVENLAFAXINE
|
Heart Damage
|
less
|
increases in blood pressure
|
mild
|
NUPLAZID
|
PIMAVANSERIN TARTRATE
|
pimavanserin tartrate
|
Arrhythmia
|
most
|
QT Interval Prolongation
|
moderate
|
Venclexta
|
VENETOCLAX
|
Venetoclax
| null |
no
|
no large effect on QTc interval
| null |
SLYND
|
DROSPIRENONE
|
DROSPIRENONE
| null |
no
| null | null |
Linzess
|
LINACLOTIDE
|
LINACLOTIDE
| null |
ambiguous
|
hypotension and electrolyte abnormalities (hypokalemia and hyponatremia)
|
mild
|
Myrbetriq
|
MIRABEGRON
|
MIRABEGRON
|
Heart Damage
|
less
|
increase blood pressure
|
mild
|
STEGLATRO
|
ERTUGLIFLOZIN
|
ERTUGLIFLOZIN PIDOLATE
| null |
no
|
not prolong QTc
| null |
RAZADYNE
|
GALANTAMINE HYDROBROMIDE
|
galantamine hydrobromide
|
Arrhythmia
|
most
|
heart block
|
moderate
|
Daypro
|
OXAPROZIN
|
OXAPROZIN
|
Heart Damage
|
most
|
myocardial infarction
|
severe
|
Stivarga
|
REGORAFENIB
|
REGORAFENIB MONOHYDRATE
|
Heart Damage
|
most
|
myocardial ischemia and infarction
|
severe
|
ACCRUFER
|
FERRIC MALTOL
|
FERRIC MALTOL
| null |
no
| null | null |
LAMPIT
|
NIFURTIMOX
|
NIFURTIMOX
| null |
ambiguous
|
Hypersensitivity reaction:hypotension
| null |
PEXEVA
|
PAROXETINE MESYLATE
|
PAROXETINE MESYLATE
|
Mixed
|
less
|
tachycardia/angina pectoris
|
mild
|
GEMTESA
|
VIBEGRON
|
vibegron
| null |
no
|
not prolong QTc
| null |
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