Biomedical-TeMU/CodiEsp_corpus · Datasets at Hugging Face

text stringlengths 0 4.13k
Chest X-ray and abdominal ultrasound were normal.
1.
Brucella serology, Epsteins anomaly (VEB) and cytomegalovirus (CMV) were negative.
Laboratory tests showed normal blood count, erythrocyte sedimentation rate (GSR) of 47 mm/hour and interferon-gamma release assays (IGRA) (QuantiFERON(r) value: 0.150.35).
A needle aspiration biopsy (FNAB) of the adenopathy showed a whitish thick material.
Culture and cytological study revealed a pattern of necrotizing granulomatous lymphadenitis.
Given the scarce affectation of the patient and the suspicion of tuberculous adenitis, an initial home treatment with isoniazid, rifampicin and pyrazinamide was initiated, waiting for the culture of the sample obtained by FNAB.
The culture was positive for M. bovis, presenting an antibiogram with pyrazinamide resistance and sensitivity to streptomycin, etambuco, isoniazid and rifampicin.
Pyrazinamide was prescribed for this reason during two months, followed by isoniazid and rifampicin for six months.
Mycobacterium cultures in gastric juices were negative.
During this time the patient went to periodic reviews in the Pediatric Infectious Diseases Department, in which a good clinical evolution and complete resolution of the infectious process were observed.
We report the case of a 40-year-old male patient, polytoxicated since adolescence, with a first admission to prison at 20 years, and repeated admissions later.
In 1993, HIV and HCV coinfection was detected.
Its clinical history consists of the prescription of the first mental disorder in 1998, with constant abandonment, especially during periods of freedom.
Other pathologies of interest:
- pneumocystitis jirovecii pneumonia (formerly known as carinii) in 1998
- recurrent community acquired pneumonia
- oropharyngeal and probably esophageal candidiasis,
- pulmonary TB and cerebral lesions due to toxoplasmosis and/or TB
- practically constant seborrheic dermatitis
In August 2009 he presented crusted, scaly, non-pruriginous lesions of scalp onset, auricular pavilions and armpits.
Subsequently, these lesions extended to the trunk and extremities, including soles and palms of feet and hands.
Similar lesions in the interglottic and genital folds also appeared.
The dermatologist advised the patient to present psoriasis, receiving treatment with calcipotriol plus betamethasone, salicylic vaseline and tracolimus 0.1%.
This treatment was not initiated until a new imprisonment in early 2010.
A slight improvement has been seen in recent weeks.
At the beginning of the clinical picture, the CD4+ cell/ml lymphocyte count was 64 with an HIV CV of 1,090,000 copies/ml (6.04 log).
He also had significant cachexia (BMI < 16) and anemia (Hbina of 10 g/dl; Htcto.
The patient refuses to speak.
Currently, in hospital admission to study possible etymology of brain lesions.
A 46-year-old male, with no relevant medical history, nonsmoker.
She underwent fixed rehabilitation on a single implant (ITI® SLA).
Straumann.
Walderburg-Switzerland) placed in zone 3.6.
Six months after cementing the crown, the patient came to control with no associated symptoms.
Clinical examination revealed slight redness of the mucosa adjacent to the implant and a 6 mm deep peri-implant pocket with mild bleeding on probing.
The role of joint showed premature contact with prosthetic crown.
Panoramic radiography showed a radiolucent area in the marginal bone at 3.6.
The prosthetic crown was occlusally carved.
Subsequently, a mucoperitic flap was raised from 3.5 to 3.7, a marginal flap of fibrous tissue occupying a peri-implant bone defect at 3.6.
The pathological tissue was removed with plastic curettes and sent for anatomopathological study.
The implant surface was tapered with 0.2% chlorhexidine gel for 2 minutes and irrigation with saline.
The flap was extended to access a lingual mandibular torus in ipsilateral premolar area, which was extracted and articulated to serve as a self-injection.
The flap was repositioned and sutured with 3.0 silk.
The patient was re-instructed in oral hygiene, ibuprofen 600 mg every 8 hrs x 4 days and eyedrops with chlorhexidine digluconate 0.12% twice a day x 2 weeks.
Histopathological analysis showed an epithelial connective tissue with abundant lymphoplasmacytic and juxtaepithelial infiltrate.
Dense fibroconnective tissue with few inflammatory cells was observed under the superficial area.
Twelve months after the surgical treatment, a radiograph showed marginal bone recovery and a normal clinical appearance, with no symptoms.
In June 2003, a 40-year-old female patient, resident of a population originated from the City of Guatemala, presented to consultation referred by her general dentist with an asymptomatic brownish brownish pigmented macule.
The lesion was located in the anterior hard palate mucosa measuring 0.5 cm in diameter.
The patient had no relevant medical history and was in good health.
She said she didn't take any medication.
The patient had lost upper teeth due to extractions and used a removable partial acrylic prosthesis, inadequately designed that caused pressure erythema to the underlying mucosa. Candidiasis was ruled out by cytology.
1.
An excisional biopsy was performed under local anesthesia, using the sacralisation technique with a 0.6 cm diameter instrument.
The surgical site healed by second intention without complications.
The tissue obtained from the biopsy was fixed in buffered formalin at 10% and fixed routinely.
The microscopic study of the same, with hematoxylin-eosin staining, revealed a fragment of mucosa coated by stratified squamous epithelium slightly acanthotic, with connective tissue disease containing numerous spongocytosis.
The underlying connective tissue showed the presence of melanine pigment admixed to a mild inflammatory infiltrate predominantly lymphocytic.
Definitive diagnosis was osteonecrosis.
A 42-year-old woman presented to the Maxillofacial Surgery Department of the Marqués demandibular Valde la Santander University Hospital (España), with complaints of discomfort in the right temporal joint.
The patient reported right TMJ clicks of years of evolution without further clinical accompanying symptoms.
Physical examination revealed no dentoskeletal anomalies.
The patient had a maximum painless oral opening (MAO) of 45 mm, reciprocal TMJ click (at the beginning of the opening and at the end of the closure).Laterodeviation and pterygoid process greater than 10 mm.
A panoramic radiograph was performed in which the left condylar duplication was observed.
1.
Magnetic resonance imaging (MRI) of both TMJ demonstrated the presence of anterior displacement of the disc that reduced to the opening in the right TMJ.
The morphology of the condyle stood out in the left TMJ: anteroposterior bifidity and presence of grade II joint effusion.
To complete the imaging study, a computerized tomography (CT) of both TMJs was requested, confirming the existence of anteroposterior left bifid condyle without evidence of degenerative changes.
1.
The patient was treated conservatively with a discharge splint, muscle relaxants, local heat and soft diet.
This treatment improved clinically and is currently followed in routine outpatient follow-up in our service.
We report the case of a 43-year-old man who consulted for a palpable mass, painful to pressure in the right preauricular region.
Physical examination revealed a poorly defined 2 cm mass in the right parotid area, with no other significant findings.
The patient reported no personal or family history of interest, only the nodule mentioned above, which, as indicated, had evolved for more than five years.
The imaging tests performed, computerized axial tomography and ultrasound, show a well-defined 2.5 x 2 cm tumor focused on the parotid, which does not affect bone or muscle structures, suggestive of low-grade tumor.
1.
Puncture aspiration was performed with needle dyeing, using the routine method of 3 passes with 23G needle, and help of Cameco® (manual aspirate device) technique was used after which the rest were fixed in alcohol.
The examination of the extended samples shows, on a seroproteinaceous background, abundant cellularity of large size, with central and occasionally peripheral nuclei, rounded, poorly patent and fine granular chromatin.
The cytoplasm is very characteristic, being abundant, pale and foamy edges unisolated, vacuolized and containing abundant violet granules.
Cells are arranged in more or less compact groups of large two-dimensional laminae, sometimes adopting an acinar architectural pattern.
Along with this predominant cellularity, smaller size cells with low cytoplasm and small rounded or oval central nucleus are also observed.
The cytological image was therefore consistent with serous acinar cell disease, probably carcinoma, so it was proposed to perform DNA quantification by imaging cytometry on cytological smears.
Since the smears obtained in the first puncture did not allow an adequate evaluation, a second FNA was performed with the purpose of progressive staining of Hematology, and the material for the cytometric determination was subsequently fixed with methyl alcohol 99.
1.
By means of the TEXCAN® software and through integrated video camera, a histoploid (Symploid-like) form was revealed (Symploid-type), captures gray scales, and determines the most relevant biological parameters.
With the cytological diagnosis of acinar cell carcinoma and the low-grade cytometric prognostic index, a conservative surgical intervention was performed, with excision of the parotid gland without cervical fixation and preserving the nerve.
Macroscopically, we found a whitish piece of polylobulated morphology with a weight of 12 grams and total measurements of 8 x 4 x 3 cm. At the cut, we found an apparently non-extremely cystic lesion of 1.5 cm.
We performed multiple parallel sections of the sample, which were embedded in paraffin and then stained with conventional hematoxylin-eosin.
Histopathological study shows a well circumscribed microcystic and solid neoformation composed mainly of acinar cells that do not overflow the glandular capsule.
The multiple cystic spaces of very small size, located between solid sheets are formed by luces covered by intercalated ductal cells, although acinar cells also participate occasionally.
Acinar cells are serously secreted, as demonstrated by PAS staining (Schiff periodic) highlighting intracystic acid eosinophilic zymogenic granules as well as intracytoplasmic acid secretion.
The neoplasm respects the extremes of resection and there is no evidence of vascular or nerve damage.
1.
The definitive diagnosis is therefore a low-grade, well-defined, malignant neoplasm of Acinar Cells without invasion of surgical extremes.
This is a 40-year-old female patient who comes to her bedside physician with daytime sleepiness and frequent nocturnal awakenings of months of evolution to which now an important temporary tension-type headache was added.
The patient was referred to the pneumologist with suspected sleep apnea syndrome, which was ruled out by appropriate tests, including polysomnography.
Since the painful component was increasing, the patient was referred to our Orofacial Pain Unit.
The clinical examination revealed a class 2 occlusion with slight occlusal wear, as well as signs and symptoms of masticatory muscle pain due to myofascial syndrome with both trigger points in masticatory muscles and covering.
The patient also complained of back pain, heavy digests and meteorism.

Chest X-ray and abdominal ultrasound were normal.

1.

Brucella serology, Epsteins anomaly (VEB) and cytomegalovirus (CMV) were negative.

Laboratory tests showed normal blood count, erythrocyte sedimentation rate (GSR) of 47 mm/hour and interferon-gamma release assays (IGRA) (QuantiFERON(r) value: 0.150.35).

A needle aspiration biopsy (FNAB) of the adenopathy showed a whitish thick material.

Culture and cytological study revealed a pattern of necrotizing granulomatous lymphadenitis.

Given the scarce affectation of the patient and the suspicion of tuberculous adenitis, an initial home treatment with isoniazid, rifampicin and pyrazinamide was initiated, waiting for the culture of the sample obtained by FNAB.

The culture was positive for M. bovis, presenting an antibiogram with pyrazinamide resistance and sensitivity to streptomycin, etambuco, isoniazid and rifampicin.

Pyrazinamide was prescribed for this reason during two months, followed by isoniazid and rifampicin for six months.

Mycobacterium cultures in gastric juices were negative.

During this time the patient went to periodic reviews in the Pediatric Infectious Diseases Department, in which a good clinical evolution and complete resolution of the infectious process were observed.

We report the case of a 40-year-old male patient, polytoxicated since adolescence, with a first admission to prison at 20 years, and repeated admissions later.

In 1993, HIV and HCV coinfection was detected.

Its clinical history consists of the prescription of the first mental disorder in 1998, with constant abandonment, especially during periods of freedom.

Other pathologies of interest:

- pneumocystitis jirovecii pneumonia (formerly known as carinii) in 1998

- recurrent community acquired pneumonia

- oropharyngeal and probably esophageal candidiasis,

- pulmonary TB and cerebral lesions due to toxoplasmosis and/or TB

- practically constant seborrheic dermatitis

In August 2009 he presented crusted, scaly, non-pruriginous lesions of scalp onset, auricular pavilions and armpits.

Subsequently, these lesions extended to the trunk and extremities, including soles and palms of feet and hands.

Similar lesions in the interglottic and genital folds also appeared.

The dermatologist advised the patient to present psoriasis, receiving treatment with calcipotriol plus betamethasone, salicylic vaseline and tracolimus 0.1%.

This treatment was not initiated until a new imprisonment in early 2010.

A slight improvement has been seen in recent weeks.

At the beginning of the clinical picture, the CD4+ cell/ml lymphocyte count was 64 with an HIV CV of 1,090,000 copies/ml (6.04 log).

He also had significant cachexia (BMI < 16) and anemia (Hbina of 10 g/dl; Htcto.

The patient refuses to speak.

Currently, in hospital admission to study possible etymology of brain lesions.

A 46-year-old male, with no relevant medical history, nonsmoker.

She underwent fixed rehabilitation on a single implant (ITI® SLA).

Straumann.

Walderburg-Switzerland) placed in zone 3.6.

Six months after cementing the crown, the patient came to control with no associated symptoms.

Clinical examination revealed slight redness of the mucosa adjacent to the implant and a 6 mm deep peri-implant pocket with mild bleeding on probing.

The role of joint showed premature contact with prosthetic crown.

Panoramic radiography showed a radiolucent area in the marginal bone at 3.6.

The prosthetic crown was occlusally carved.

Subsequently, a mucoperitic flap was raised from 3.5 to 3.7, a marginal flap of fibrous tissue occupying a peri-implant bone defect at 3.6.

The pathological tissue was removed with plastic curettes and sent for anatomopathological study.

The implant surface was tapered with 0.2% chlorhexidine gel for 2 minutes and irrigation with saline.

The flap was extended to access a lingual mandibular torus in ipsilateral premolar area, which was extracted and articulated to serve as a self-injection.

The flap was repositioned and sutured with 3.0 silk.

The patient was re-instructed in oral hygiene, ibuprofen 600 mg every 8 hrs x 4 days and eyedrops with chlorhexidine digluconate 0.12% twice a day x 2 weeks.

Histopathological analysis showed an epithelial connective tissue with abundant lymphoplasmacytic and juxtaepithelial infiltrate.

Dense fibroconnective tissue with few inflammatory cells was observed under the superficial area.

Twelve months after the surgical treatment, a radiograph showed marginal bone recovery and a normal clinical appearance, with no symptoms.

In June 2003, a 40-year-old female patient, resident of a population originated from the City of Guatemala, presented to consultation referred by her general dentist with an asymptomatic brownish brownish pigmented macule.

The lesion was located in the anterior hard palate mucosa measuring 0.5 cm in diameter.

The patient had no relevant medical history and was in good health.

She said she didn't take any medication.

The patient had lost upper teeth due to extractions and used a removable partial acrylic prosthesis, inadequately designed that caused pressure erythema to the underlying mucosa. Candidiasis was ruled out by cytology.

1.

An excisional biopsy was performed under local anesthesia, using the sacralisation technique with a 0.6 cm diameter instrument.

The surgical site healed by second intention without complications.

The tissue obtained from the biopsy was fixed in buffered formalin at 10% and fixed routinely.

The microscopic study of the same, with hematoxylin-eosin staining, revealed a fragment of mucosa coated by stratified squamous epithelium slightly acanthotic, with connective tissue disease containing numerous spongocytosis.

The underlying connective tissue showed the presence of melanine pigment admixed to a mild inflammatory infiltrate predominantly lymphocytic.

Definitive diagnosis was osteonecrosis.

A 42-year-old woman presented to the Maxillofacial Surgery Department of the Marqués demandibular Valde la Santander University Hospital (España), with complaints of discomfort in the right temporal joint.

The patient reported right TMJ clicks of years of evolution without further clinical accompanying symptoms.

Physical examination revealed no dentoskeletal anomalies.

The patient had a maximum painless oral opening (MAO) of 45 mm, reciprocal TMJ click (at the beginning of the opening and at the end of the closure).Laterodeviation and pterygoid process greater than 10 mm.

A panoramic radiograph was performed in which the left condylar duplication was observed.

1.

Magnetic resonance imaging (MRI) of both TMJ demonstrated the presence of anterior displacement of the disc that reduced to the opening in the right TMJ.

The morphology of the condyle stood out in the left TMJ: anteroposterior bifidity and presence of grade II joint effusion.

To complete the imaging study, a computerized tomography (CT) of both TMJs was requested, confirming the existence of anteroposterior left bifid condyle without evidence of degenerative changes.

1.

The patient was treated conservatively with a discharge splint, muscle relaxants, local heat and soft diet.

This treatment improved clinically and is currently followed in routine outpatient follow-up in our service.

We report the case of a 43-year-old man who consulted for a palpable mass, painful to pressure in the right preauricular region.

Physical examination revealed a poorly defined 2 cm mass in the right parotid area, with no other significant findings.

The patient reported no personal or family history of interest, only the nodule mentioned above, which, as indicated, had evolved for more than five years.

The imaging tests performed, computerized axial tomography and ultrasound, show a well-defined 2.5 x 2 cm tumor focused on the parotid, which does not affect bone or muscle structures, suggestive of low-grade tumor.

1.

Puncture aspiration was performed with needle dyeing, using the routine method of 3 passes with 23G needle, and help of Cameco® (manual aspirate device) technique was used after which the rest were fixed in alcohol.

The examination of the extended samples shows, on a seroproteinaceous background, abundant cellularity of large size, with central and occasionally peripheral nuclei, rounded, poorly patent and fine granular chromatin.

The cytoplasm is very characteristic, being abundant, pale and foamy edges unisolated, vacuolized and containing abundant violet granules.

Cells are arranged in more or less compact groups of large two-dimensional laminae, sometimes adopting an acinar architectural pattern.

Along with this predominant cellularity, smaller size cells with low cytoplasm and small rounded or oval central nucleus are also observed.

The cytological image was therefore consistent with serous acinar cell disease, probably carcinoma, so it was proposed to perform DNA quantification by imaging cytometry on cytological smears.

Since the smears obtained in the first puncture did not allow an adequate evaluation, a second FNA was performed with the purpose of progressive staining of Hematology, and the material for the cytometric determination was subsequently fixed with methyl alcohol 99.

1.

By means of the TEXCAN® software and through integrated video camera, a histoploid (Symploid-like) form was revealed (Symploid-type), captures gray scales, and determines the most relevant biological parameters.

With the cytological diagnosis of acinar cell carcinoma and the low-grade cytometric prognostic index, a conservative surgical intervention was performed, with excision of the parotid gland without cervical fixation and preserving the nerve.

Macroscopically, we found a whitish piece of polylobulated morphology with a weight of 12 grams and total measurements of 8 x 4 x 3 cm. At the cut, we found an apparently non-extremely cystic lesion of 1.5 cm.

We performed multiple parallel sections of the sample, which were embedded in paraffin and then stained with conventional hematoxylin-eosin.

Histopathological study shows a well circumscribed microcystic and solid neoformation composed mainly of acinar cells that do not overflow the glandular capsule.

The multiple cystic spaces of very small size, located between solid sheets are formed by luces covered by intercalated ductal cells, although acinar cells also participate occasionally.

Acinar cells are serously secreted, as demonstrated by PAS staining (Schiff periodic) highlighting intracystic acid eosinophilic zymogenic granules as well as intracytoplasmic acid secretion.

The neoplasm respects the extremes of resection and there is no evidence of vascular or nerve damage.

1.

The definitive diagnosis is therefore a low-grade, well-defined, malignant neoplasm of Acinar Cells without invasion of surgical extremes.

This is a 40-year-old female patient who comes to her bedside physician with daytime sleepiness and frequent nocturnal awakenings of months of evolution to which now an important temporary tension-type headache was added.

The patient was referred to the pneumologist with suspected sleep apnea syndrome, which was ruled out by appropriate tests, including polysomnography.

Since the painful component was increasing, the patient was referred to our Orofacial Pain Unit.

The clinical examination revealed a class 2 occlusion with slight occlusal wear, as well as signs and symptoms of masticatory muscle pain due to myofascial syndrome with both trigger points in masticatory muscles and covering.

The patient also complained of back pain, heavy digests and meteorism.