20240309_am24_abstract_topic_model

This is a BERTopic model. BERTopic is a flexible and modular topic modeling framework that allows for the generation of easily interpretable topics from large datasets.

Usage

To use this model, please install BERTopic:

pip install -U bertopic

You can use the model as follows:

from bertopic import BERTopic
topic_model = BERTopic.load("djordan/20240309_am24_abstract_topic_model")

topic_model.get_topic_info()

Topic overview

  • Number of topics: 175
  • Number of training documents: 8265
Click here for an overview of all topics.
Topic ID Topic Keywords Topic Frequency Label
-1 Immunotherapy and Tumor Microenvironment - - - - 5 Immunotherapy and Tumor Microenvironment
0 Cancer Survival and Healthcare Access - - - - 3778 Cancer Survival and Healthcare Access
1
Chimeric Antigen Receptor T Cell Therapy for B-Cell Malignancies - - - - 429 Chimeric Antigen Receptor T Cell Therapy for B-Cell Malignancies
2 Glioblastoma research and treatment - - - - 186 Glioblastoma research and treatment
3 "3D Organoid Culture in Cancer Research" - - - - 168 3D Organoid Culture in Cancer Research
4 Kras G12C Inhibitors and Resistance - - - - 160 Kras G12C Inhibitors and Resistance
5
Acute Myeloid Leukemia Treatment and Drug Screening - - - - 154 Acute Myeloid Leukemia Treatment and Drug Screening
6 Spatial imaging of tissue microenvironments - - - - 120 Spatial imaging of tissue microenvironments
7 Prostate cancer and AR degradation - - - - 112 Prostate cancer and AR degradation
8 Parp Inhibition and DNA Damage Repair - - - - 110 Parp Inhibition and DNA Damage Repair
9 Pancreatic Ductal Adenocarcinoma (PDAC) Microenvironment - - - - 99 Pancreatic Ductal Adenocarcinoma Microenvironment
10 Topoisomerase 1 Inhibitors Adc Development - - - - 92 Topoisomerase 1 Inhibitors Adc Development
11 Hepatocellular Carcinoma Treatment Research - - - - 85 Hepatocellular Carcinoma Treatment Research
12 EGFR-TKIs and Resistance Mechanisms in Non-Small Cell Lung Cancer - - - - 78 EGFR-TKIs and Resistance Mechanisms in Non-Small Cell Lung Cancer
13 Glutamine Metabolism in Cervical Cancer - - - - 76 Glutamine Metabolism in Cervical Cancer
14
"Nanoparticle-based cancer treatment" - - - - 67 Nanoparticle-based cancer treatment
15 Bone metastasis in breast cancer - - - - 56 Bone metastasis in breast cancer
16 Microbiome and Immunotherapy in Cancer - - - - 54 Microbiome and Immunotherapy in Cancer
17 Triple Negative Breast Cancer (TNBC) - - - - 51 Triple Negative Breast Cancer
18
Oral Squamous Cell Carcinoma (OSCC) Research - - - - 48 Oral Squamous Cell Carcinoma Research
19 Melanoma therapy and Braf inhibitors - - - - 46 Melanoma therapy and Braf inhibitors
20 Immunomodulation of Glioblastoma with Sting Agonism - - - - 45 Immunomodulation of Glioblastoma with Sting Agonism
21
"Anticancer mechanisms of natural compounds" - - - - 41 Anticancer mechanisms of natural compounds
22 Renal Cell Carcinoma Subtypes - - - - 41 Renal Cell Carcinoma Subtypes
23
"Liquid Biopsy Using Urine and Plasma Samples" - - - - 40 Liquid Biopsy Using Urine and Plasma Samples
24 Award ceremony speech draft - - - - 39 Award ceremony speech draft
25
TCR-engineered therapy for cancer treatment - - - - 38 TCR-engineered therapy for cancer treatment
26 T-cell engagers for cancer treatment - - - - 38 T-cell engagers for cancer treatment
27 Colorectal cancer research - - - - 37 Colorectal cancer research
28 Obesity and breast cancer - - - - 36 Obesity and breast cancer
29 Ferroptosis in cancer treatment - - - - 36 Ferroptosis in cancer treatment
30 Trop2-targeted ADCs for cancer treatment - - - - 34 Trop2-targeted ADCs for cancer treatment
31 Hippo pathway inhibitors - - - - 34 Hippo pathway inhibitors
32 Immunotherapy in mice - - - - 33 Immunotherapy in mice
33
Clinical trials of immunotherapies - - - - 32 Clinical trials of immunotherapies
34 Immunity checkpoint inhibitors and resistance - - - - 29 Immunity checkpoint inhibitors and resistance
35 Pancreatic cancer research - - - - 29 Pancreatic cancer research
36 Drug combination screening - - - - 28 Drug combination screening
37
Pancreatic Cancer Research - - - - 27 Pancreatic Cancer Research
38 Her2 expression in solid tumors - - - - 26 Her2 expression in solid tumors
39 Smoking-induced lung cancer research - - - - 26 Smoking-induced lung cancer research
40
"Stk11 Loss Drives Anti-PD1 Resistance in Lung Cancer" - - - - 26 Stk11 Loss Drives Anti-PD1 Resistance in Lung Cancer
41 Prostate cancer research and treatment - - - - 25 Prostate cancer research and treatment
42 Cyclin-dependent kinase 2 inhibition in cancer therapy - - - - 25 Cyclin-dependent kinase 2 inhibition in cancer therapy
43
"Methylation Detection from Cell-Free DNA" - - - - 25 Methylation Detection from Cell-Free DNA
44 Medulloblastoma research and treatment - - - - 25 Medulloblastoma research and treatment
45 Single-cell RNA sequencing and chromatin accessibility analysis - - - - 24 Single-cell RNA sequencing and chromatin accessibility analysis
46
"MTA-PRMT5 Inhibitors for Cancer Treatment" - - - - 24 MTA-PRMT5 Inhibitors for Cancer Treatment
47 Anti-PD-1 therapy in NSCLC - - - - 24 Anti-PD-1 therapy in NSCLC
48 Immunomodulation with IL-18 and PD-1 antagonists - - - - 24 Immunomodulation with IL-18 and PD-1 antagonists
49 RMS and Pax3-Foxo1 Fusion Protein Research - - - - 24 RMS and Pax3-Foxo1 Fusion Protein Research
50
"Chromatin organization and gene regulation in breast cancer" - - - - 24 Chromatin organization and gene regulation in breast cancer
51 Multi-Cancer Early Detection Tests - - - - 23 Multi-Cancer Early Detection Tests
52
Mitochondrial dysfunction in cancer - - - - 23 Mitochondrial dysfunction in cancer
53 Cholangiocarcinoma research and treatments - - - - 23 Cholangiocarcinoma research and treatments
54 Immune cell analysis with cytof - - - - 23 Immune cell analysis with cytof
55
"Circulating Tumor DNA Monitoring in Cancer Treatment" - - - - 23 Circulating Tumor DNA Monitoring in Cancer Treatment
56 Cellular thermal shift assay (CTSA) for target engagement - - - - 22 Cellular thermal shift assay for target engagement
57 "FFPE Library Prep Methods" - - - - 21 FFPE Library Prep Methods
58
"Lung Cancer Classification and Targeting" - - - - 21 Lung Cancer Classification and Targeting
59 Immunotherapy biomarkers in cancer patients - - - - 20 Immunotherapy biomarkers in cancer patients
60 Colorectal cancer genomics and mutations - - - - 20 Colorectal cancer genomics and mutations
61 Epithelial-mesenchymal transition and plasticity in cancer - - - - 20 Epithelial-mesenchymal transition and plasticity in cancer
62 Electric fields for cancer treatment - - - - 19 Electric fields for cancer treatment
63 Cancer-associated fibroblasts in tumor microenvironment - - - - 19 Cancer-associated fibroblasts in tumor microenvironment
64
Prostate cancer research and diagnosis - - - - 19 Prostate cancer research and diagnosis
65
Acquired drug resistance and persister cells - - - - 19 Acquired drug resistance and persister cells
66
"EAC and Barrett's Esophagus Research" - - - - 19 EAC and Barrett's Esophagus Research
67
"Lung Cancer Research" - - - - 18 Lung Cancer Research
68
"Cachexia and Muscle Wasting in Cancer Patients" - - - - 18 Cachexia and Muscle Wasting in Cancer Patients
69 Cloud-based data governance for cancer research - - - - 17 Cloud-based data governance for cancer research
70 Ewing Sarcoma Research - - - - 17 Ewing Sarcoma Research
71
"Immunotherapy targeting Tregs" - - - - 16 Immunotherapy targeting Tregs
72
Nano-immunotherapy for cancer treatment - - - - 16 Nano-immunotherapy for cancer treatment
73
"Trial of T-1101 and T-1201 in Cancer Treatment" - - - - 16 Trial of T-1101 and T-1201 in Cancer Treatment
74 Radiation and Immunity in Cancer Treatment - - - - 16 Radiation and Immunity in Cancer Treatment
75 Immunotherapy and Neoantigens - - - - 15 Immunotherapy and Neoantigens
76 Aging and immune system in cancer - - - - 15 Aging and immune system in cancer
77
Progesterone and breast cancer - - - - 14 Progesterone and breast cancer
78
"Gut Microbiome in CRC Patients" - - - - 14 Gut Microbiome in CRC Patients
79 Hematopoiesis and Clonal Variants - - - - 14 Hematopoiesis and Clonal Variants
80
"Kinase Inhibition and Targeting" - - - - 14 Kinase Inhibition and Targeting
81 Paralog selective degraders for cancer therapy - - - - 13 Paralog selective degraders for cancer therapy
82
"Immunotherapy for Melanoma" - - - - 13 Immunotherapy for Melanoma
83 Genome-scale measurements for tumor normal benchmark - - - - 13 Genome-scale measurements for tumor normal benchmark
84 Immunotherapy for bladder cancer - - - - 13 Immunotherapy for bladder cancer
85 Hematopoietic Progenitor Kinase 1 Inhibition - - - - 13 Hematopoietic Progenitor Kinase 1 Inhibition
86
Variants of Uncertain Significance (VUS) - - - - 13 Variants of Uncertain Significance
87
"Colorectal cancer detection" - - - - 13 Colorectal cancer detection
88 Claudin18 Targeted Therapy - - - - 13 Claudin18 Targeted Therapy
89
"AI-based tumor purity analysis" - - - - 13 AI-based tumor purity analysis
90 Bispecific antibody development for cancer treatment - - - - 13 Bispecific antibody development for cancer treatment
91
"Genomic Variant Detection" - - - - 12 Genomic Variant Detection
92 Prostate cancer in African men - - - - 12 Prostate cancer in African men
93
"Microsatellite Instability and WRN Helicase Inhibition" - - - - 12 Microsatellite Instability and WRN Helicase Inhibition
94 Immunosuppression and antibody-enhancing drugs - - - - 12 Immunosuppression and antibody-enhancing drugs
95
"Immune Checkpoint Inhibitor Adverse Events" - - - - 12 Immune Checkpoint Inhibitor Adverse Events
96 Neuronal influence on cancer growth - - - - 12 Neuronal influence on cancer growth
97 "Uveal Melanoma and Selenoproteome Expression" - - - - 11 Uveal Melanoma and Selenoproteome Expression
98 HBV and HCC Treatment Studies - - - - 11 HBV and HCC Treatment Studies
99
Btk Inhibitors and Resistance Mechanisms - - - - 11 Btk Inhibitors and Resistance Mechanisms
100
"Tertiary Lymphoid Structures in Cancer Prognosis" - - - - 11 Tertiary Lymphoid Structures in Cancer Prognosis
101 Extrachromosomal DNA in cancer research - - - - 11 Extrachromosomal DNA in cancer research
102 Smarca2/4 degraders for cancer treatment - - - - 11 Smarca2/4 degraders for cancer treatment
103
"Epigenetic Regulators and Cancer Treatment" - - - - 11 Epigenetic Regulators and Cancer Treatment
104 Bispecific anti-egfr/cmet adc - - - - 11 Bispecific anti-egfr/cmet adc
105 Transposable elements and cancer - - - - 10 Transposable elements and cancer
106
"ER Degradation Therapy for Breast Cancer" - - - - 10 ER Degradation Therapy for Breast Cancer
107 Macrophage-based therapies in cancer - - - - 10 Macrophage-based therapies in cancer
108
"Genomic Alterations in NSCLC" - - - - 10 Genomic Alterations in NSCLC
109 Bladder Cancer Diagnosis and Monitoring - - - - 10 Bladder Cancer Diagnosis and Monitoring
110
"Genomic profiling for cancer diagnosis" - - - - 10 Genomic profiling for cancer diagnosis
111 TCR Repertoire in Cancer Patients - - - - 10 TCR Repertoire in Cancer Patients
112 Kras Vaccine Development - - - - 10 Kras Vaccine Development
113
"G-quadruplex Targeting Compound in Pancreatic Cancer Treatment" - - - - 9 G-quadruplex Targeting Compound in Pancreatic Cancer Treatment
114
Clinical efficacy of dual Her2 inhibition in metastatic colorectal cancer (MCRC) - - - - 9 Clinical efficacy of dual Her2 inhibition in metastatic colorectal cancer
115 Liquid biopsy for glioma monitoring - - - - 9 Liquid biopsy for glioma monitoring
116
Mismatch repair and immune checkpoint inhibitors - - - - 9 Mismatch repair and immune checkpoint inhibitors
117
"Immunomodulatory effects of mushroom consumption in prostate cancer." - - - - 9 Immunomodulatory effects of mushroom consumption in prostate cancer.
118 Nectin-4 targeted ADCs - - - - 9 Nectin-4 targeted ADCs
119 Single-cell gene expression technologies - - - - 9 Single-cell gene expression technologies
120
Head and neck cancer subtyping - - - - 9 Head and neck cancer subtyping
121 Cancer Vaccine Development - - - - 8 Cancer Vaccine Development
122 Proteomic analysis of cancer tissues - - - - 8 Proteomic analysis of cancer tissues
123
"Lymphoma Prognostics and Treatment Strategies" - - - - 8 Lymphoma Prognostics and Treatment Strategies
124
"Chemotherapy Resistance Mechanisms in Colorectal Cancer" - - - - 8 Chemotherapy Resistance Mechanisms in Colorectal Cancer
125 Cancer-associated fibroblasts research - - - - 7 Cancer-associated fibroblasts research
126
Condensate-based drug discovery - - - - 7 Condensate-based drug discovery
127
"Metabolism and Cancer Treatment" - - - - 7 Metabolism and Cancer Treatment
128 Stat3 degraders for cancer therapy - - - - 7 Stat3 degraders for cancer therapy
129 Melanoma research and embryonic development - - - - 7 Melanoma research and embryonic development
130
"Ovarian Cancer Biomarkers" - - - - 7 Ovarian Cancer Biomarkers
131
LncRNA and Promoter Regulation in Cancer - - - - 7 LncRNA and Promoter Regulation in Cancer
132 Immunotherapy in cancer treatment - - - - 7 Immunotherapy in cancer treatment
133
"Ferroptosis in Cancer Cells" - - - - 7 Ferroptosis in Cancer Cells
134
"Cdk4 Inhibitors and Breast Cancer Resistance" - - - - 7 Cdk4 Inhibitors and Breast Cancer Resistance
135 Radiation therapy and DNA damage response inhibitors - - - - 7 Radiation therapy and DNA damage response inhibitors
136 Liquid biopsy for cancer diagnosis and treatment response. - - - - 7 Liquid biopsy for cancer diagnosis and treatment response.
137 Brain Metastasis Survival Analysis - - - - 7 Brain Metastasis Survival Analysis
138
Molecular Biomarkers in Breast Cancer - - - - 7 Molecular Biomarkers in Breast Cancer
139
P53 and RPL22 in Cancer - - - - 7 P53 and RPL22 in Cancer
140 Colorectal cancer research - - - - 7 Colorectal cancer research
141
"Tumor Suppression Mechanisms" - - - - 7 Tumor Suppression Mechanisms
142 Radiation-induced salivary gland damage and regeneration - - - - 7 Radiation-induced salivary gland damage and regeneration
143
"Adenosine Signaling and Immunotherapy" - - - - 7 Adenosine Signaling and Immunotherapy
144 Sarcopenia and ICI in NSCLC - - - - 7 Sarcopenia and ICI in NSCLC
145 Ethnic disparities in lymphoma survival - - - - 7 Ethnic disparities in lymphoma survival
146 Liquid biopsy for lung cancer screening - - - - 7 Liquid biopsy for lung cancer screening
147
"KDM6A Loss in Urothelial Carcinomas" - - - - 7 KDM6A Loss in Urothelial Carcinomas
148 Immuno-oncology screens with CRISPR and RNA-seq - - - - 6 Immuno-oncology screens with CRISPR and RNA-seq
149 P53 Restoration Therapy - - - - 6 P53 Restoration Therapy
150 Immunometabolic targeting in cancer immunotherapy - - - - 6 Immunometabolic targeting in cancer immunotherapy
151
"Breast cancer recurrence and gene regulation" - - - - 6 Breast cancer recurrence and gene regulation
152 Head and neck squamous cell carcinoma (HNSCC) research - - - - 6 Head and neck squamous cell carcinoma research
153
"HCC Immune Cells Study" - - - - 6 HCC Immune Cells Study
154
"Pd-L1 IHC Scoring Methods" - - - - 6 Pd-L1 IHC Scoring Methods
155 Ovarian Cancer Glycosylation and Metastasis - - - - 6 Ovarian Cancer Glycosylation and Metastasis
156
"Ubiquitin-Proteasome System in Cancer Treatment" - - - - 6 Ubiquitin-Proteasome System in Cancer Treatment
157
Clinical Study of Hbw-3220 and Lp-284 in Aggressive Non-Hodgkin Lymphoma - - - - 6 Clinical Study of Hbw-3220 and Lp-284 in Aggressive Non-Hodgkin Lymphoma
158 Immunotherapy in Non-Small Cell Lung Cancer - - - - 6 Immunotherapy in Non-Small Cell Lung Cancer
159 Anlotinib + Chemo for Advanced Escc Treatment - - - - 6 Anlotinib + Chemo for Advanced Escc Treatment
160
"Myc Targeting Technologies" - - - - 6 Myc Targeting Technologies
161 Neuroblastoma Epigenetics Study - - - - 5 Neuroblastoma Epigenetics Study
162
"Metastasis and Genetic Alterations" - - - - 5 Metastasis and Genetic Alterations
163 T Cell Exhaustion and Stemness Programs - - - - 5 T Cell Exhaustion and Stemness Programs
164
Prostate cancer research - - - - 5 Prostate cancer research
165
"Lung Cancer Microenvironment Analysis" - - - - 5 Lung Cancer Microenvironment Analysis
166
"Pi3k/Akt Inhibitors in Breast Cancer" - - - - 5 Pi3k/Akt Inhibitors in Breast Cancer
167
"Liquid Biopsy Analysis of Whole Blood for Cancer Diagnosis" - - - - 5 Liquid Biopsy Analysis of Whole Blood for Cancer Diagnosis
168 Extracellular Vesicle Research in Ovarian Cancer - - - - 5 Extracellular Vesicle Research in Ovarian Cancer
169 Colorectal Cancer Secondary Malignancies in Young Adults - - - - 5 Colorectal Cancer Secondary Malignancies in Young Adults
170 Molecular Glues Targeting Cancer-Specific E3 Ligases - - - - 5 Molecular Glues Targeting Cancer-Specific E3 Ligases
171 Epigenetics and Cancer Research - - - - 5 Epigenetics and Cancer Research
172 Immunogenic neoantigens and NMD inhibition in cancer immunotherapy - - - - 5 Immunogenic neoantigens and NMD inhibition in cancer immunotherapy
173 Click Activated Prodrugs Against Cancer Platform - - - - 5 Click Activated Prodrugs Against Cancer Platform

Training hyperparameters

  • calculate_probabilities: False
  • language: None
  • low_memory: False
  • min_topic_size: 10
  • n_gram_range: (1, 1)
  • nr_topics: None
  • seed_topic_list: None
  • top_n_words: 10
  • verbose: True
  • zeroshot_min_similarity: 0.7
  • zeroshot_topic_list: None

Framework versions

  • Numpy: 1.25.2
  • HDBSCAN: 0.8.33
  • UMAP: 0.5.5
  • Pandas: 1.5.3
  • Scikit-Learn: 1.2.2
  • Sentence-transformers: 2.6.0.dev0
  • Transformers: 4.39.0.dev0
  • Numba: 0.58.1
  • Plotly: 5.15.0
  • Python: 3.10.12
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