In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
Alcohol travels through the intestines to the liver and then on to the heart, brain, muscles and other tissues. This happens very quickly-within a few minutes. Usually, though not always, this has a pleasant effect. Your body canât store alcohol, so it breaks it down-your liver's job. The liver firstly changes alcohol into acetaldehyde (this is toxic), then into acetate (harmless), which is finally broken down into carbon dioxide and water. Find out more about how alcohol can effect you from our interactive male and female bodies. About 90-95% of alcohol consumed is broken down by the liver, 5-10% is excreted through urine, breath and sweat.Your bodyâs ability to process alcohol depends on your age, weight and sex.