Do dogs make sounds when they are content? My dog always comes up to me asking for me to pet him, and while I do he always make tiny, barely audible noises.They sound almost like a mix of a purr and a sigh. Is that how dog&#39;s express happiness?y dog always comes up to me asking for me to pet him, and while I do he always make tiny, barely audible noises. They sound almost like a mix of a purr and a sigh.
The International Council on Harmonisation (ICH) defines an institutional review board (IRB) as a group formally designated to protect the rights, safety and well-being of humans involved in a clinical trial by reviewing all aspects of the trial and approving its startup. IRBs can also be called independent ethics committees (IECs). An IRB/IEC reviews the appropriateness of the clinical trial protocol as well as the risks and benefits to study participants. It ensures that clinical trial participants are exposed to minimal risks in relation to any benefits that might result from the research.
An independent IRB is subject to the same federal and state regulatory requirements applicable to all IRBs. A significant percentage of independent IRBs are accredited. In 1998, the Office of the Inspector General for the Department of Health and Human Services issued a report noting that independent IRBs offer a number of benefits, such as: