In the 1946 elections to the Indian constituent assembly, the Congress lost the Muslim vote to the Muslim League; it reluctantly accepted the partition of the Indian subcontinent and the formation of the state of Pakistan. After partition the Congress, as the largest party, governed India under Nehru's leadership.
ACTH is a hormone produced in the anterior pituitary gland that stimulates the adrenal glands to release cortisol, dehydroepiandrosterone (DHEA), dehydroepiandrosterone sulfate (DHEA-S), and aldosterone.
The release of ACTH is regulated by the corticotropin-releasing hormone (CRH) from the hypothalamus in response to normal physiologic rhythms. A variety of stressors can also influence its release, and the role of ACTH in the stress response is discussed later in this chapter.