If one is talking about interstate business, a company that is in one state provides its products and services to a customer in another state or several states. Intrastate. Intrastate refers to anything that pertains to a single state and does not require crossing over the boundaries of a single state.
H. pylori was first discovered in the stomachs of patients with gastritis and ulcers in 1982 by Drs. Barry Marshall and Robin Warren of Perth, Australia. At the time, the conventional thinking was that no bacterium could live in the acid environment of the human stomach.
But H pylori infection, IS an INFECTION and this infection causes inflammation in the lining of the stomach. Sometimes to a great degree, sometimes to a lesser degree. It's this inflammation which causes any number of symptoms, or no symptoms at all! Generally none of which are consistent from person to person.