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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
1 Donors are in constant demand as platelets have a shelf-life of only five days. 2  Types most needed: A+, A-, B+, B-, AB+, AB-.  Donate every two weeks, (24 times/year); two days later, you can donate whole blood. You must wait 56 days to donate again after giving whole blood.