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One common cause of muscle aches and pain is fibromyalgia, a condition that causes tenderness in your muscles and surrounding soft tissue, sleep difficulties, fatigue, and headaches.
What is the significance of muscle tenderness? A person with muscle tenderness has muscle pain when pressure is applied to the skin over a muscle. Muscle tenderness is commonly associated with a muscle injury, such as a muscle strain or a muscle rupture. Causes of muscle tenderness include torticollis, fibromyalgia, rhabdomyolysis, polymyositis, tick borne illness, Lyme disease, drug side effects and muscle infections.