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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
Red blood cells are the oxygen carrying cells. They can take two weeks or longer to fully return to normal. You can donate platelets (apheresis donation) every two weeks â up to 24 times in 12 months. Platelet and plasma components are regenerated in the body more quickly than red cells. Platelets will return to normal levels within 24-48 hours of donating.