2 doctors agreed: CFTR: Cystic fibrosis is caused by a mutation of the cftr gene, or cystic fibrosis transmembrane regulator, on chromosome 7. Cftr works as a chloride ion channel which helps to regulate chloride and sodium movement in your lungs and sweat ducts. ...Read more.
1. JKJones (Pharmacist (Verified)) - 11 / 08 / 2010. Desquamation is the natural shedding and peeling of the outermost layers of the skin. When there is damage to the skin or this process is interrupted or changed, there may be additional shedding and peeling.
Lichenification is thickening of the skin with accentuation of normal skin markings; it results from repeated scratching or rubbing. Induration, or deep thickening of the skin, can result from edema, inflammation, or infiltration, including by cancer. Indurated skin has a hard, resistant feeling. Induration is characteristic of panniculitis, some skin infections, and cutaneous metastatic cancers.