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Myelodysplastic syndromes (MDS). 1  Is a diagnosis of cancer. 2  Is a group of diseases of the blood and bone marrow, with varying degrees of severity, treatment needs and life expectancy. 3  May be primary (de novo) or treatment-related. 4  Primary MDS has no obvious cause.
Medical Definition of Myelodysplastic syndrome. Myelodysplastic syndrome: One of a group of disorders characterized by abnormal development of one or more of the cell lines that are normally found in the bone marrow. Patients can develop a variety of symptoms related to anemia, low or high white blood cell count, infections, and bleeding problems.