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Standing is a natural human posture and by itself poses no particular health hazard. However, working in a standing position on a regular basis can cause sore feet, swelling of the legs, varicose veins, general muscular fatigue, low back pain, stiffness in the neck and shoulders, and other health problems.
If i stand up or sitdown or move really, i will sometimes have a 5-15 second blackout where i loose all my senses and if im standing have to hold on to something to avoid falling over, which doesn't always work, and i end up falling straight backwards. They happen around 5-10 times a week.