In addition, thiazolidinediones have several other potential side effects, which make them less appealing as initial or second step therapy. (See 'Cardiovascular effects' below and 'Safety' below.). The pharmacology and use of thiazolidinediones will be reviewed here.
Alcohol impairs brain areas such as the cerebellumâthe control site for your balance and coordinationâand your cerebral cortex, which is responsible for thinking, memory, and learning, says Kimberly S. Walitzer, Ph.D., deputy director of the University at Buffaloâs Research Institute on Addictions.
Detrimental influences upon brain development. 1  Alcohol abuse: Drinking excessive amounts of alcohol to the point of abuse may have an impact on the developing brain. It is critical to avoid abusing alcohol while the brain is still developing as excess drinking can disrupt formation of the prefrontal cortex.