Substance use disorder occurs when a person needs alcohol or another substance (drug) to function normally. Abruptly stopping the substance leads to withdrawal symptoms. Addiction means that a person has a strong urge to use the substance and cannot stop, even if they want to.
So it is important to maintain positive nitrogen balance in the body while sleeping. When you do and conditions are right so that your rate of protein synthesis exceeds your rate of degradation, and you maintain a positive nitrogen balance, you can grow while you sleep.
The first REM sleep period usually occurs about 70 to 90 minutes after we fall asleep. A complete sleep cycle takes 90 to 110 minutes on average. The first sleep cycles each night contain relatively short REM periods and long periods of deep sleep.