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The new film obviously takes place before the Harry Potter movies, but exactly when does Fantastic Beasts and Where to Find Them take place? In case you couldn't tell by the fanciful dress of its characters, the movie takes place in the roaring 1920s. Specifically, it takes place in New York City in the year 1926.
Scamander himself does not appear in the seven Harry Potter books. He is mentioned in passing in Harry Potter and the Philosopher's Stone as the author of Fantastic Beasts and Where to Find Them. He is the central character of the film adaptation of Fantastic Beasts and Where to Find Them portrayed by Eddie Redmayne.