n. 1. Physical or mental weariness resulting from effort or activity. 2. Something, such as tiring effort or activity, that causes tiredness or weariness: the fatigue of a long hike. 3. Physiology The decreased capacity or complete inability of an organism, organ, or part to function normally because of excessive stimulation or prolonged exertion. 4.
blood - the fluid (red in vertebrates) that is pumped through the body by the heart and contains plasma, blood cells, and platelets; blood carries oxygen and nutrients to the tissues and carries away waste products; the ancients believed that blood was the seat of the emotions
Blood plasma is a yellowish coloured liquid component of blood that normally holds the blood cells in whole blood in suspension; this makes plasma the extracellular matrix of blood cells. It makes up about 55% of the body's total blood volume. It is the intravascular fluid part of extracellular fluid (all body fluid outside cells).