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Immune system disorders cause abnormally low activity or over activity of the immune system. In cases of immune system over activity, the body attacks and damages its own tissues (autoimmune diseases). Immune deficiency diseases decrease the body's ability to fight invaders, causing vulnerability to infections.
Other dysregulation of the immune system includes autoimmune diseases such as lupus and rheumatoid arthritis. Finally, some less common disease related to deficient immune system conditions are antibody deficiencies and cell mediated conditions that may show up congenitally, Lau told Live Science.isorders of the immune system can result in autoimmune diseases, inflammatory diseases and cancer, according to the NIH. Immunodeficiency occurs when the immune system is not as strong as normal, resulting in recurring and life-threatening infections, according to the University of Rochester Medical Center.