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THE SUPRACHIASMATIC NUCLEI AND THE PINEAL GLAND. Most human bodily functions and behaviours are not âsteady-stateâ. Instead, they fluctuate in 24-hour cycles, such as the sleeping and waking cycle and the cycles for body temperature, hunger, and the secretion of various hormones.
The primary circadian clock in mammals is located in the suprachiasmatic nucleus (or nuclei) (SCN), a pair of distinct groups of cells located in the hypothalamus. Destruction of the SCN results in the complete absence of a regular sleepâwake rhythm.