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Clindamycin does not interact with coumadin directly, though clindamycin is shown to cause liver damage, If this is the case the coumadin can increase INR greater than expected..Regards, kindly click ACCEPT if i have answered to your satisfation, a positive feedback and a bonus will be highly appreciated..esolved Question: my mother take coumadin and was given clindamycin for a tooth infection. Her INR is now 4.8. Her dentist told her that the antibiotic should not interact with her coumadin.
CLEOCIN PEDIATRIC (clindamycin palmitate HCl) is indicated in the treatment of. serious infections caused by susceptible anaerobic bacteria. Clindamycin is also indicated in the treatment of serious infections due to susceptible. strains of streptococci, pneumococci and staphylococci. Its use should be reserved for. penicillin-allergic patients or other patients for whom, in the judgment of the physician, a. penicillin is inappropriate.