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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
Call the blood bank or clinic if you feel sick within 24 hours after giving blood. Your body will replace the lost fluid in 24 hours. (It takes a few weeks to replace red blood cells.) You will have to wait 56 days before you can give whole blood again. 1 | 2 | 3.n the hours after you give blood, make sure to: 1  Drink plenty of fluids to help replace the lost fluid. 2  Eat foods that have a lot of iron, such as lean red meat, raisins, and beans. 3  Limit your physical activity for several hours.