Substance use disorder occurs when a person needs alcohol or another substance (drug) to function normally. Abruptly stopping the substance leads to withdrawal symptoms. Addiction means that a person has a strong urge to use the substance and cannot stop, even if they want to.
So it is important to maintain positive nitrogen balance in the body while sleeping. When you do and conditions are right so that your rate of protein synthesis exceeds your rate of degradation, and you maintain a positive nitrogen balance, you can grow while you sleep.
After stage 3 sleep, stage 2 sleep is repeated before entering REM sleep. Once REM sleep is over, the body usually returns to stage 2 sleep. Sleep cycles through these stages approximately four or five times throughout the night. On average, we enter the REM stage approximately 90 minutes after falling asleep. The first cycle of REM sleep might last only a short amount of time, but each cycle becomes longer. REM sleep can last up to an hour as sleep progresses.