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1 Serotonin is a chemical that affects mood, emotion, sleep and appetite. 2  Many antidepressants affect the amount of serotonin in the brain, and can also affect a personâs sleep.3  People beginning treatment with a new antidepressant may feel drowsier than usual for the first couple of weeks. Serotonin is a chemical that affects mood, emotion, sleep and appetite. 2  Many antidepressants affect the amount of serotonin in the brain, and can also affect a personâs sleep.
Prozac and other antidepressant increase serotonin levels. Drink warm milk at night â help you sleep because contains and amino acid that brain uses to make serotonin (relax). Plays a role in schizophrenia, may interact with dopamine system to alter the way it operates.