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Answer Wiki. Summary: peak running performance after donating blood may be impacted for up to 1-2 weeks after donating 1 pint of blood, but is most noticeably impacted within the first 1-2 days after donating when attempting to perform at peak levels during endurance activities.
1 Apheresis platelet donation â you must wait 14 days between donations. 2  Athletics â you should avoid strenuous activities for at least three to five hours after donating and no heavy lifting for rest of the day.  Blood transfusions â you must wait one year after receiving a blood transfusion before you can donate.