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1 Achalasia. 2  Achalasia is a condition that affects the smooth muscle portion of the esophagus, that is, the lower esophagus and the lower esophageal sphincter. 3  Specifically, the peristaltic wave disappears, and the lower sphincter does not relax.
Learning objectives: Disorders affecting the neuromuscular junction (NMJ) are among the most interesting. and rewarding seen in the EMG laboratory. These disorders are generally pure motor. syndromes that usually preferentially affect proximal, bulbar, or extraocular muscles. They are confused occasionally with myopathies.