Living with a depressed person is very difficult, indeed. Friends and family members may try to "cheer them up", or attempt to persuade them that things aren't as bad as the depressed person feels they are. That never works, and often makes the person suffering from depression sink deeper. Depressed people often carry within them the feeling that nothing can be done, and nothing will change.  But medication and/or talk therapy, depending on the individual, can be highly effective. When someone who's depressed resists getting help, that becomes frustrating, and almost unbearable for the people around them.  Getting angry with them doesn't help either.  It's a great relief when a depressed person gets help and feels better, or the depression lifts on its own, as it sometimes does.  People with repeated episodes of depression can learn to weather the storm, and realize that when they're low, getting help is useful, or if they're lucky, it will simply pass.