The animosity is that Israel is pursuing policies that are antithetical to US interests and a detriment to any peaceful settlement in the Mid-East. The thorn in the side of the Arab nations, the thing that was help push the formation of al Qaeda and ISIS, is that intransigence of Israel to settling Palestinian question. It is a problem caused when Israel forced Palestinians out of the home and off their land making them a homeless, refugee population. Compounded over the years with actions an that include war crimes and a deliberate policy apartheid Israel has done nothing but pour duel on the fire of Arab resentment. America, Americans, and the rest of the civilized world can decry and criticize Israeli policy and actions without being anti-Semitic. This consistent use of charging critics with being anti-Semitic is counter productive to the peace process, and blunts any recognition of real anti-Semites.