All of the following statements regarding theophylline are true except:
Theophylline is a methylxanthine , used in the treatment of bronchial asthma. Its dose has to be reduced in elderly (age > 60years), in congestive hea failure, pneumonia and liver failure. Ref: Essentials of Medical Pharmacology, 5th Edition, Page 203
Increases cAMP
Inhibits phosphodiesterase
Increase in dose is required in smokers
Increase in dose is required in cardiopulmonary disease
Increase in dose is required in cardiopulmonary disease