Which of the following autoantibodies is most likely to be present in a patient with SLE?
Ans. A. Anti-ds DNAAnti-ds DNA is present in 65% cases of SLE and is a marker of development of lupus nephritis.Anti Ro is present in 30% cases and is a marker of cutaneous lupus and development of congenital CHB in the baby of mother with SLE. Anti-phospholipid are present in 40% cases and are a marker of recurrent fetal loss and thrombosis.Anti-ribosomal P antibody is present in 20% cases only and is a marker of psychosis
Immunology and Rheumatology
Anti-ds DNA
Anti Ro
Anti-Phospholipid
Anti-Ribosomal P
Anti-ds DNA