In Bater syndrome the defect lies in?
Bater Syndrome- defect in thick ascending limb of loop of Henle *Loss of function of (Na+ Cl- K+ co transpoer) *Damage to ROMK & Cl- channel C/F: 1. Hypokalemia, salt wasting 2. Normal BP 3.Met. Alkalosis Dx: 24 hr. urine chloride : elevated *24 hr. urine Ca2+ : elevated DOC: indomethacin
Bater syndrome, Gitelman syndrome, Liddle and Comparison with SIADH
Distal convoluted tubule
Thick ascending limb of loop of Henle
Thin ascending limb of loop of Henle
Proximal convoluted tubule
Thick ascending limb of loop of Henle