Gigantism is due to:
- Excess GH results in: overgrowth / gigantism during childhood with open epiphysis * After fusion of epiphysis - ACROMEGALY - Features of Acromegaly: Coarse facies large tongue Prognathism(protruded lower jaw) thick skin broad nose headache & visual field defects - Best screening test - IGF 1 levels - TREATMENT: Somatostatin analogues (Octreotide) GH Receptor antagonist (Pegvisomant)
Disorders of Pituitary Gland
Increased secretion of coisol
Decreased secretion of coisol
Increased secretion of growth hormone
Decreased secretion of growth hormone
Increased secretion of growth hormone