Histamine causes all EXCEPT:
Platelet aggregation REF: Robbin's pathology 7th edition page 63 Preformed histamine is present in mast cell granules and is released by mast cell degranulation in response to variety of stimuli. In humans histamine causes: Aeriolar dilatation Increased permeability of venules (however constricts large aeries) Via binding to H1 receptor on endothelial cells
Aeriolar dilatation
Increased permeability of venules
Constriction of large aeries
Platelet aggregation
Platelet aggregation