A major source of collagen in cirrhosis -
Perisinusoidal stellate cells (Ito cells) play a role in the storage and metabolism of vitamin A and are transformed into collegen producing myofibroblasts when there is inflamation of the liver.
These cells are the major source of collagen in cirrhosis
Kupffer cells
Ito cell (Hepatic stellate cell)
Hepatocyte
Canalicular cell
Ito cell (Hepatic stellate cell)