Cell mediated immunity is markedly depressed in
(B) Lepromatous leprosy# In untreated LL patients, lymphocytes regularly fail to recognize either M. leprae or its protein constituents, and lepromin skin tests are negative.> This loss of protective cellular immunity appears to be antigen-specific, as patients are not unusually susceptible to opportunistic infections, cancer, or AIDS and maintain delayed-type hypersensitivity to Candida, Trichophyton, mumps, tetanus toxoid, and even purified protein derivative of tuberculin.> Lepromatous leprosy, has the greatest number of bacilli and is characterized by early, widespread, ill-defined, erythematous or hypopigmented papules and plaques. Later findings include facial infiltration (leonine facies), ocular effects, neurologic involvement, and hypogonadism.
Misc.
Tuberculoid leprosy
Lepromatous leprosy
Polyneuritic form of leprosy
Indeterminate leprosy
Lepromatous leprosy