Rofecoxib as compared to indomethacin is :
Selective COX-2 inhibitors are less likely to cause GI complications like PUD. However a COX-2 is also present constitutively in the kidney, chances of renal complications are similar. These drugs have similar or less efficacy than non-selective COX inhibitors.
Less likely to cause gastric ulcer and their complications
Likely to be more effective in rheumatoid arthritis
Not likely to produce renal complications
All of the above
Less likely to cause gastric ulcer and their complications