Which of the following enzymes require Vitamin C for their activity?
Vitamin C plays the role of a coenzyme in hydroxylation of proline and lysine while protocollagen is converted to collagen  (i.e.  post-translational modification). The hydroxylation reaction is catalysed by lysyl hydroxylase  (for  lysine)  and prolyl  hydroxylase (for  proline).
Procollagen proline hydroxylase
Procollagen amino peptidase
Procollagen carboxyl peptidase
Lysyl oxidase
Procollagen proline hydroxylase