Gene responsible for Van der woude syndrome:
Mutations in the IRF6 gene that cause van der Woude syndrome prevent one copy of the gene in each cell from making any functional protein. A shortage of the IRF6 protein affects the development and maturation of tissues in the face, resulting in the signs and symptoms of van der Woude syndrome.
IRF6
FGFR2
HGHF2
GAT02
IRF6