Enzyme replacement is mostly done for:
Ans. (c) Gaucher's diseaseRef: Harper's Biochemistry, 30th ed. pg. 251Management of Gaucher's Disease* Regular, intravenous enzyme therapy is currently the treatment of choice in affected patients and is highly efficacious and safe in diminishing the hepatosis and improving bone marrow involvement and hematologic findings.* Symptomatic management of the blood cytopenias and joint replacement continue to have important roles in management* The bone disease is decreased but not eliminated by enzyme therapy. Adults benefit from adjunctive treatment with bisphosphonates to improve bone mass.
Lipids
Niemann pick's
Gangliosidosis
Gaucher's disease
Phenylketonuria
Gaucher's disease