The following serum levels: calcium- 7.8 mg/ dL, 25 hydroxy vitamin D is high, 1 a-hydroxylase levels are low. Which drug shall be the most appropriate for treatment of this condition?
The above scenario is of vitamin D dependent rickets type 1. VITAMIN D DEFICIENCY RICKETS Autosomal recessive Presents as childhood rickets | Calcium and | activity of 1a hydroxylase Do not respond to conventional doses of vitamin D. Rx- Calcitriol (0.25-0.5 mcg daily).
Metabolic Disorders of Bone
Calcitriol
Phosphate supplementation
Calcifediol
Vitamin D3
Calcitriol