The most impoant action of beta-blockers in glaucoma is :
Ref: KD Tripathi pharmacology 7th edition (page.no: 144) Topical b blockers are one of the first-line drug for glaucoma In contrast to miotics, the b blockers do not affect pupil size, the tone of ciliary muscle or outflow facility, but lower i.o.t. by reducing aqueous formation. This probably results from down-regulation of adenylyl cyclase due to b 2 receptor blockade in the ciliary epithelium and a secondary effect due to a reduction in ocular blood flow.
Autonomic nervous system
Membrane stabilizing effect
Refinal neuron protecting effect
Decrease in the production of aqueous humor
Pupillary constriction
Decrease in the production of aqueous humor