Skin depigmentation, bilateral uveitis and tinnitus are features of –
Vogt Koyanagi - Harada (VKH) syndrome

It is an idiopathic multisystem disorder which includes cutaneous, neurological and ocular lesions.
The disease is comparatively more common in Japanese who are usually positive for HLA-DR4 and DW15.

Clinical features


Cutaneous lesions include: alopecia, poliosis and vitiligo.


Neurological lesions are in the form of meningism, encephalopathy, tinnitus, vertigo and deafness.


Ocular features are bilateral chronic granulomatous anterior uveitis, posterior uveitis and exudative retinal detachment.
Vogt Koyanagi harada syndrome
Waardenburg Syndrome
Alport Syndrome
Werner's Syndrome
Vogt Koyanagi harada syndrome