An infant presents with the condition as shown below after a pharyngeal infection. The shown condition is:
SSSS/ Pemphigus Neonatorum / Ritter's disease: - Caused by: Staph. aureus - Seen in neonates and infants - Usually follows pharyngeal infection. - Staph. aureus releases Exfoliative toxins A & B that destroys Desmoglein 1 - Mucosal involvement absent - Epidermal separation occurs superficially. - Nikolsky sign positive - when pressure applied tangentially to skin, overlying epidermis will separate. Treatment of SSSS - Usually requires hospitalisation i/v antibiotics are given. A penicillinase-resistant, anti-staphylococcal antibiotic such as flucloxacillin is used. Other antibiotics include nafcillin, oxacillin, cephalosporin and clindamycin.
Bacterial infections
Staphylococcal scalded skin syndrome
Epidermolysis bullosa simplex
Impetigo contagiosa
Pemphigus foliaceus
Staphylococcal scalded skin syndrome