All of the following statements about trientine use in Wilson's disease are true except:
*Penicillamine is the most potent chelating agent useful in Wilson's disease. *Trientine is not as potent as penicillamine and was used in patients unable to tolerate penicillamine.However,now a days, trientine is preferred because of severe adverse effects of penicillamine. *Trientine cause fewer adverse effects other than mild anemia due to iron deficiency in few patients. Ref: KATZUNG 14TH ED.
Central Nervous system
It is more potent than penicillamine.
It is used as an alternative to penicillamine in non-tolerant patients
It should not be administered with in two hours of iron supplementation
It can cause iron def anemia which is reversible by oral iron supplements
It is more potent than penicillamine.