In which of the following disorders, administration of barbiturates is contraindicated
Barbiturates induce the rate-limiting enzyme δ-amino clavulanic acid synthase' in porphyrin synthesis. This increased synthesis of porphyrins can precipitate an acute attack of AIP.
Anxiety disorders
Acute intermittent porphyria
Kernicterus
Refractory status epilepticus
Acute intermittent porphyria