In renal disease albumin is first to appear in urine because
Ans. (b) Has molecular weight slightly greater than the molecules normally getting filtered(Ref: Ganong, 25th ed/p.677)Glomerular membrane permits neutral substances up to 4 nm in diameter. Substances greater than 8nm diameter are totally excludedAlbumin size is 7 nm. So, it has molecular weight slightly greater than the molecules normally getting filtered
Kidneys and Body Fluids
Of its high concentration in plasma
Has molecular weight slightly greater than the molecules normally getting filtered
High albumin : globulin ratio
Tubular epithelial cells are sensitive to albumin
Has molecular weight slightly greater than the molecules normally getting filtered