All of the following statements is/are true about post streptococcal glomerulonephritis except -
Only ceain strains of group A Beta-hemolytic streptococci are nephritogenic, more than 90% of cases been traced to types 12,4 & 1, which can be identified by typing of M protein of cell wall. Electron microscopy shows deposited immune complexes arrayed as subendothelial, intramembranous, or most often, subepithelial 'humps' nestled against the GBM. Ref: Pathologic basis of disease ROBBINS 8th edition, pg no:917 & ROBBINS basic pathology 9th edition, pg no:529
Urinary tract
Early treatment of streptococcal pharyngitis prevents glomerulonephritis
All cases of streptococcal infection lead to glomerulonephritis
Hump sign may be present
Immune complex deposits are seen
All cases of streptococcal infection lead to glomerulonephritis