A violent manic patient should not be treated with:
(Ref: Goodman & Gillman 13th ed. P 281-282)* For acute manic attacks, preferred agents are atypical antipsychotics, benzodiazepines, anticonvulsants (Valproate, carbamazepine), Lithium* All atypical antipsychotics medications with the exception of clozapine, iloperidone, brexpiprazole, and lurasidone, have indications for acute mania, and doses are titrated rapidly close to or at the maximum FDA- approved dose over the first 24-72 hours of treatment. Typical antipsychotic drugs are also effective in acute mania, but often are eschewed due to the risk for EPSs.
C.N.S
Benzodiazepines
Cognitive therapy
Atypical antipsychotics
Quetiapine
Cognitive therapy