In a child with acute liver failure, the most important abnormal serum biochemical test that indicates poor prognosis:
C. Increasing prothrombin time(Ref: Nelson's 20/e p 1967)Hepatic synthetic function is reflected in serum albumin and protein levels and in the PT or INRUnresponsiveness of PT to vitamin K suggests severe hepatic diseasePersistently low levels of factor VII are evidence of a poor prognosis in fulminant liver diseaseSerum aminotransferase activities do not correlate well with the severity of the illness.
Gastro Intestinal System
Increasing transaminases
Increasing bilirubin
Increasing prothrombin time
Reversal of serum albumin-globulin ratio
Increasing prothrombin time