Mechanism of resistance of tetracyclines is due to?
Mechanism of Resistance Examples Enzymatic breakdown A: Aminoglycosides B: Beta lactams C: Chloramphenicol Decreased permeability Aminoglycosides Efflux pumps Tetracyclines Altered metabolic pathway Sulfonamides Altered target MRSA Vancomycin, Fluoroquinolones
JIPMER 2019
Drug efflux mechanism
Development of inactivating enzymes
DNA methylation
Cell wall alteration
Drug efflux mechanism