Acclimatization does not include:
Acclimatization: The respiratory alkalosis produced by the hyperventilation shifts the oxygen-hemoglobin dissociation curve to the left, but a concomitant increase in red blood cell 2,3-BPG tends to decrease the O2 affinity of hemoglobin. The net effect is a small increase in P50 (right shift).
Erythropoietin secretion increases promptly on ascent to high altitude. The increase in circulating red blood cells triggered by the erythropoietin begins in 2-3 days and is sustained as long as the individual remains at high altitude.
Hyperventilation
Decreased concentration of 2,3 DPG in RBC
Increased erythropoiesis
Kidney excrete more alkali
Decreased concentration of 2,3 DPG in RBC