Menke's kinky (Steely) hair disease occurs due to:
Menke's kinky hair disease- X-linked defect in intestinal absorption of copper. Mutation in ATP7A gene. Low levels of copper and ceruloplasmin. C/F- Progressive cerebral degeneration, growth retardation Sparse brittle hair Scurvy-like bone changes Anemia and neutropenia Failure to thrive Pili toi, trichorrhexis and monilethrix may occur.
Wilson Disease
Low copper levels
Low zinc levels
Low iron levels
Low fluoride levels
Low copper levels