subject
string | txt_report
string | gold_diagnosis
string | cognitive_txt
string |
|---|---|---|---|
FTLD_203138707_01703_MR_Sagittal_MP-Rage_br_raw_20230124212017175_I10178606
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum maintains a normal appearance with no observable atrophic features
- no observable atrophic changes in the hippocampus
- no clear atrophic alterations are visible in the amygdala
- accumbens appears within normal limits without apparent atrophy
- thalamus maintains a normal appearance with no observable atrophic features
- putamen appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the caudate
For the ventricles:
- no appreciable enlargement noted in the external csf
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
- no findings suggestive of enlargement are seen in the 4th ventricle
- inf. lateral ventricle maintains its expected proportions without signs of enlargement
- 3rd ventricle maintains a typical volume without observable enlargement
For the cerebral cortex:
- no observable atrophic changes in the temporal lobe
- occipital lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the parietal lobe
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: lateral orbital gyrus (mild atrophy both left/right), subcallosal area (mild atrophy both left/right), frontal pole (normal on the left and mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left and normal on the right)
- insular cortex maintains a normal appearance with no observable atrophic features
- limbic cortex maintains a normal appearance with no observable atrophic features
|
CN
|
We have the following subject's personal information:
- The subject is a female of 49.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 15 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 23.
- On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 28, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 48, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203023197_01792_MR_Sagittal_MP-Rage_br_raw_20230209092223055_I10183099
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the temporal lobe shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the limbic cortex
- mild-to-moderate atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and normal on the right), postcentral gyrus medial segment (mild atrophy on the left), precuneus (mild atrophy on the left and normal on the right) and sup. parietal lobule (mild atrophy on the left and normal on the right)
- no clear atrophic alterations are visible in the insular cortex
- the occipital lobe shows no notable changes suggestive of atrophy
- moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), triangular inf. frontal gyrus (mild atrophy both left/right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), opercular inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right), frontal pole (mild atrophy on the left and normal on the right) and gyrus rectus (mild atrophy on the left)
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the amygdala
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- moderate atrophy of the left putamen and mild atrophy of the right putamen
- mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus
- moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- mild-to-moderate bilateral atrophy of the accumbens
- hippocampus maintains a normal appearance with no observable atrophic features
For the ventricles:
- severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
- 4th ventricle maintains its expected proportions without signs of enlargement
- severe enlargement of the 3rd ventricle
|
SV
|
We have the following subject's personal information:
- The subject is a female of 62.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 23.
- On the semantic categorical fluency test, the subject named 5 animals in 60 seconds. She named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 0.
- On the Trail Making Test Part A, her total number of seconds to complete is 150, her number of commission errors is 6, her number of correct lines is 1.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in depression or dysphoria, a mild (noticeable, but not significant) change in anxiety, disinhibition, motor disturbance.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203920337_02732_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177238
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- parietal lobe appears within normal limits without apparent atrophy
- moderate-to-severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), fusiform gyrus (mild atrophy both left/right), planum polare (mild atrophy on the left and normal on the right) and inf. temporal gyrus (mild atrophy on the left and normal on the right)
- moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy on the left and mild atrophy on the right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), subcallosal area (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (mild atrophy both left/right), lateral orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), sup. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), opercular inf. frontal gyrus (normal on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right) and medial frontal cortex (mild atrophy on the left and normal on the right)
- occipital lobe appears preserved, with no observable tissue loss
- moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild-to-moderate atrophy on the left) and parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right) and central operculum (mild atrophy on the left and normal on the right)
For the subcortical structures:
- moderate-to-severe atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- severe atrophy of the left putamen and mild atrophy of the right putamen
- mild atrophy of the left pallidum; the right pallidum is normal
- severe atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- moderate-to-severe atrophy of the left accumbens and moderate atrophy of the right accumbens
- mild-to-moderate atrophy of the left thalamus; the right thalamus is normal
- severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
For the ventricles:
- severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- moderate enlargement of the external csf
- mild enlargement of the 4th ventricle
- severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- moderate-to-severe enlargement of the 3rd ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a male of 62.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in disinhibition, appetite and eating, a mild (noticeable, but not significant) change in agitation or aggression, elation or euphoria, motor disturbance, nighttime behaviors.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203207681_03180_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178283
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- severe enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- 3rd ventricle maintains a typical volume without observable enlargement
- the external csf shows no notable changes suggestive of enlargement
- no appreciable enlargement noted in the 4th ventricle
- severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
For the cerebral cortex:
- no observable atrophic changes in the frontal lobe
- occipital lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (mild atrophy both left/right) and sup. temporal gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy both left/right) and postcentral gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior cingulate gyrus (mild atrophy on the left and normal on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy on the left and mild-to-moderate atrophy on the right) and anterior insula (mild atrophy both left/right)
For the subcortical structures:
- mild bilateral atrophy of the accumbens
- pallidum maintains a normal appearance with no observable atrophic features
- hippocampus demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left amygdala; the right amygdala is normal
- no appreciable degenerative or atrophic changes observed in the caudate
- no evident atrophy or tissue thinning seen in the putamen
- no evident atrophy or tissue thinning seen in the thalamus
|
BV
|
We have the following subject's personal information:
- The subject is a male of 77.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 13 animals in 60 seconds. He named 3 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 17.
- On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 3.
- On the Trail Making Test Part A, his total number of seconds to complete is 55, his number of commission errors is 1, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 4, his number of correct lines is 16.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in apathy or indifference, disinhibition, a moderate (significant, but not dramatic) change in depression or dysphoria, anxiety, irritability or lability, nighttime behaviors, appetite and eating, a mild (noticeable, but not significant) change in delusions, agitation or aggression.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203762465_03566_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047585
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the accumbens
- mild bilateral atrophy of the caudate
- early/mild-grade volumetric reduction of the right hippocampus
- no evident atrophy or tissue thinning seen in the thalamus
- pallidum demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the putamen
- amygdala maintains a normal appearance with no observable atrophic features
For the ventricles:
- no evident size increase noted in the 4th ventricle
- mild-to-moderate enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- moderate enlargement of the external csf
- mild enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the left lateral ventricle and mild enlargement of the right lateral ventricle
For the cerebral cortex:
- mild bilateral atrophy of the parietal lobe
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right)
- no evident atrophy or tissue thinning seen in the insular cortex
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild atrophy both left/right) and triangular inf. frontal gyrus (mild atrophy on the left and normal on the right)
- the temporal lobe shows no notable changes suggestive of atrophy
- occipital lobe maintains a normal appearance with no observable atrophic features
|
BV
|
We have the following subject's personal information:
- The subject is a male of 80.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 22.
- On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. He named 3 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 1.
- On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 3.
- On the Trail Making Test Part A, his total number of seconds to complete is 40, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in apathy or indifference, a moderate (significant, but not dramatic) change in motor disturbance, nighttime behaviors, appetite and eating, a mild (noticeable, but not significant) change in disinhibition, irritability or lability.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 11.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203697235_02539_MR_Sagittal_MP-Rage_br_raw_20230209103144722_I10183501
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- accumbens demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the amygdala
- no findings suggestive of atrophy are seen in the hippocampus
- mild atrophy of the right pallidum; the left pallidum is normal
- no clear atrophic alterations are visible in the putamen
- mild bilateral atrophy of the caudate
- thalamus demonstrates a healthy morphology without signs of atrophy
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the occipital lobe
- frontal lobe appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the limbic cortex
- no clear atrophic alterations are visible in the temporal lobe
- parietal lobe appears preserved, with no observable tissue loss
- no observable atrophic changes in the insular cortex
For the ventricles:
- external csf maintains a typical volume without observable enlargement
- no appreciable enlargement noted in the 4th ventricle
- mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- 3rd ventricle maintains its expected proportions without signs of enlargement
- no clear enlargement or abnormal growth seen in the lateral ventricle
|
CN
|
We have the following subject's personal information:
- The subject is a female of 28.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 29.
- On the semantic categorical fluency test, the subject named 29 animals in 60 seconds. She named 14 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 31.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 14, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 25, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203737401_03103_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178277
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- insular cortex demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the limbic cortex
- frontal lobe appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the occipital lobe
- no evident atrophy or tissue thinning seen in the parietal lobe
- temporal lobe demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- moderate bilateral enlargement of the lateral ventricle
- moderate enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
- external csf appears to be of normal dimensions, with no observable increase in size
- no clear enlargement or abnormal growth seen in the 4th ventricle
- mild enlargement of the 3rd ventricle
For the subcortical structures:
- no findings suggestive of atrophy are seen in the caudate
- pallidum appears within normal limits without apparent atrophy
- no observable atrophic changes in the accumbens
- the putamen shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the thalamus
- mild-to-moderate atrophy of the right amygdala; the left amygdala is normal
- mild atrophy of the right hippocampus
|
BV
|
We have the following subject's personal information:
- The subject is a female of 65.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 19.
- On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. She named 2 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 121, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in apathy or indifference, a mild (noticeable, but not significant) change in depression or dysphoria, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203028111_02112_MR_Sagittal_MP-Rage_br_raw_20230206154019879_I10181428
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the insular cortex shows no notable changes suggestive of atrophy
- parietal lobe maintains a normal appearance with no observable atrophic features
- occipital lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the temporal lobe
- no observable atrophic changes in the limbic cortex
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right), sup. frontal gyrus (mild atrophy on the left and normal on the right) and opercular inf. frontal gyrus (normal on the left and mild atrophy on the right)
For the ventricles:
- inf. lateral ventricle maintains a typical volume without observable enlargement
- no evident size increase noted in the 3rd ventricle
- no appreciable enlargement noted in the external csf
- lateral ventricle maintains its expected proportions without signs of enlargement
- no appreciable enlargement noted in the 4th ventricle
For the subcortical structures:
- amygdala appears within normal limits without apparent atrophy
- accumbens maintains a normal appearance with no observable atrophic features
- mild bilateral atrophy of the thalamus
- no observable atrophic changes in the pallidum
- no appreciable degenerative or atrophic changes observed in the putamen
- mild atrophy of the left caudate; the right caudate is normal
- the hippocampus shows no notable changes suggestive of atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a male of 32.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 27 animals in 60 seconds. He named 26 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 20.
- On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 7.
- On the Trail Making Test Part A, his total number of seconds to complete is 11, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 48, his number of commission errors is 0, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203708389_02980_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450121
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- severe bilateral enlargement of the inf. lateral ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
- moderate enlargement of the external csf
- 4th ventricle maintains a typical volume without observable enlargement
- mild-to-moderate bilateral enlargement of the lateral ventricle
For the cerebral cortex:
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (mild atrophy both left/right), medial frontal cortex (normal on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right), frontal pole (normal on the left and mild atrophy on the right), posterior orbital gyrus (normal on the left and mild atrophy on the right) and orbital inf. frontal gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right) and posterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right)
- mild-to-moderate atrophy of the right temporal lobe; normal-to-mild atrophy of the left temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- mild atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: parahippocampal gyrus (moderate atrophy both left/right), entorhinal area (mild atrophy on the left and mild-to-moderate atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- no observable atrophic changes in the occipital lobe
For the subcortical structures:
- mild-to-moderate atrophy of the left thalamus and moderate atrophy of the right thalamus
- moderate atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
- moderate-to-severe atrophy of the left hippocampus
- severe atrophy of the right hippocampus
- moderate atrophy of the left accumbens and moderate-to-severe atrophy of the right accumbens
- moderate atrophy of the left caudate and moderate-to-severe atrophy of the right caudate
- moderate atrophy of the left pallidum and moderate-to-severe atrophy of the right pallidum
- severe bilateral atrophy of the amygdala
|
BV
|
We have the following subject's personal information:
- The subject is a male of 63.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 24.
- On the semantic categorical fluency test, the subject named 9 animals in 60 seconds. He named 5 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 0.
- On the Trail Making Test Part A, his total number of seconds to complete is 113, his number of commission errors is 2, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in agitation or aggression, disinhibition, irritability or lability, a moderate (significant, but not dramatic) change in apathy or indifference, a mild (noticeable, but not significant) change in hallucinations, motor disturbance, nighttime behaviors, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 3.0, corresponding to severe impairment. His standard CDR sum of boxes is 15.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203342746_02644_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177765
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- moderate enlargement of the external csf
- severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
- moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- no evident size increase noted in the 4th ventricle
- mild-to-moderate enlargement of the 3rd ventricle
For the subcortical structures:
- mild atrophy of the left thalamus; the right thalamus is normal
- mild-to-moderate atrophy of the left caudate; the right caudate is normal
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- mild atrophy of the left pallidum; the right pallidum is normal
- moderate atrophy of the left putamen and mild atrophy of the right putamen
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
For the cerebral cortex:
- moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left)
- mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (mild-to-moderate atrophy both left/right), anterior insula (moderate atrophy on the left and mild atrophy on the right) and frontal operculum (mild atrophy on the left)
- mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (mild atrophy on the left and normal on the right) and precuneus (mild atrophy on the left)
- occipital lobe appears within normal limits without apparent atrophy
- frontal lobe demonstrates a healthy morphology without signs of atrophy
- severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left)
|
BV
|
We have the following subject's personal information:
- The subject is a male of 55.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in apathy or indifference, motor disturbance, a moderate (significant, but not dramatic) change in anxiety, disinhibition, appetite and eating, a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, irritability or lability, nighttime behaviors.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 8.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
|
FTLD_203877575_03577_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047595
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: angular gyrus (mild-to-moderate atrophy on the left and normal on the right), precuneus (mild atrophy on the left and normal on the right) and supramarginal gyrus (mild atrophy on the left and normal on the right)
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), middle cingulate gyrus (mild atrophy on the left) and parahippocampal gyrus (mild atrophy on the left and normal on the right)
- moderate atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: middle temporal gyrus (mild-to-moderate atrophy both left/right), sup. temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild atrophy on the left and normal on the right)
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal on the right), frontal pole (mild atrophy on the left and normal on the right), middle frontal gyrus (mild atrophy on the left and normal on the right), orbital inf. frontal gyrus (mild atrophy on the left) and medial orbital gyrus (mild atrophy on the left)
- mild bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal on the right), posterior insula (mild atrophy on the left and normal on the right) and parietal operculum (normal on the left and mild atrophy on the right)
- occipital lobe demonstrates a healthy morphology without signs of atrophy
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- moderate enlargement of the external csf
- 4th ventricle maintains a typical volume without observable enlargement
- severe enlargement of the left inf. lateral ventricle and mild-to-moderate enlargement of the right inf. lateral ventricle
For the subcortical structures:
- pallidum appears preserved, with no observable tissue loss
- mild-to-moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- no evident atrophy or tissue thinning seen in the thalamus
- mild-to-moderate atrophy of the left caudate; the right caudate is normal
- mild-to-moderate atrophy of the left putamen; the right putamen is normal
- moderate atrophy of the left amygdala and mild atrophy of the right amygdala
|
SV
|
We have the following subject's personal information:
- The subject is a female of 64.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 6.
- On the semantic categorical fluency test, the subject named 1 animals in 60 seconds. She named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 0. On the Number Span backward test, her longest span backward was 0.
- On the Trail Making Test Part A, her total number of seconds to complete is 150, her number of commission errors is 2, her number of correct lines is 10.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in anxiety, a mild (noticeable, but not significant) change in apathy or indifference, irritability or lability.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. Her standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 3.0 on language, corresponding to severe impairment.
|
FTLD_203234178_02873_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10176394
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the accumbens
- no appreciable degenerative or atrophic changes observed in the pallidum
- amygdala demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left hippocampus
- no evident atrophy or tissue thinning seen in the putamen
- thalamus demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the caudate
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- parietal lobe appears within normal limits without apparent atrophy
- temporal lobe appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the insular cortex
- frontal lobe maintains a normal appearance with no observable atrophic features
- limbic cortex maintains a normal appearance with no observable atrophic features
For the ventricles:
- external csf maintains a typical volume without observable enlargement
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
- moderate enlargement of the 3rd ventricle
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
|
CN
|
We have the following subject's personal information:
- The subject is a male of 79.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 19 animals in 60 seconds. He named 11 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 15.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 24, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 80, his number of commission errors is 1, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203798684_02489_MR_Sagittal_MP-Rage_br_raw_20230209102705784_I10183481
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the hippocampus
- no observable atrophic changes in the accumbens
- pallidum appears within normal limits without apparent atrophy
- the amygdala shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the caudate
- no appreciable degenerative or atrophic changes observed in the thalamus
- no findings suggestive of atrophy are seen in the putamen
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- no evident size increase noted in the 4th ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
- no clear enlargement or abnormal growth seen in the external csf
- inf. lateral ventricle maintains its expected proportions without signs of enlargement
For the cerebral cortex:
- no clear atrophic alterations are visible in the insular cortex
- no evident atrophy or tissue thinning seen in the frontal lobe
- the limbic cortex shows no notable changes suggestive of atrophy
- parietal lobe appears within normal limits without apparent atrophy
- occipital lobe maintains a normal appearance with no observable atrophic features
- the temporal lobe shows no notable changes suggestive of atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a female of 31.0 years old.
- She has 20.0 years of education (equivalent to doctorate)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 28.
- On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 19 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 21.
- On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 7.
- On the Trail Making Test Part A, her total number of seconds to complete is 12, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 36, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203819622_02221_MR_Sagittal_MP-Rage_br_raw_20230206184612897_I10182638
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no observable enlargement of the external csf
- lateral ventricle appears within normal size limits with no apparent enlargement
- 4th ventricle maintains its expected proportions without signs of enlargement
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- no evident size increase noted in the 3rd ventricle
For the cerebral cortex:
- no observable atrophic changes in the frontal lobe
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: inf. temporal gyrus (normal on the left and mild atrophy on the right)
- the parietal lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the limbic cortex
- no evident atrophy or tissue thinning seen in the occipital lobe
- no evident atrophy or tissue thinning seen in the insular cortex
For the subcortical structures:
- no findings suggestive of atrophy are seen in the caudate
- no clear atrophic alterations are visible in the thalamus
- putamen maintains a normal appearance with no observable atrophic features
- hippocampus maintains a normal appearance with no observable atrophic features
- accumbens demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the pallidum
- the amygdala shows no notable changes suggestive of atrophy
|
BV
|
We have the following subject's personal information:
- The subject is a male of 59.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 24 animals in 60 seconds. He named 21 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 19.
- On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 39, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 67, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in apathy or indifference, nighttime behaviors, a mild (noticeable, but not significant) change in anxiety.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203182105_03508_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450863
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right) and fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right)
- moderate atrophy of the left limbic cortex and mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild-to-moderate atrophy both left/right) and entorhinal area (mild atrophy on the left and normal on the right)
- the insular cortex does not exhibit generalized atrophy; localized volume reductions - with varying degrees of severity - are observed in anterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right)
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no evident atrophy or tissue thinning seen in the occipital lobe
- moderate atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (moderate atrophy both left/right), medial frontal cortex (moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild-to-moderate atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), frontal pole (moderate atrophy on the left and normal on the right), orbital inf. frontal gyrus (mild-to-moderate atrophy on the left and normal on the right), posterior orbital gyrus (mild-to-moderate atrophy on the left and normal on the right), subcallosal area (mild atrophy on the left and normal-to-mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left)
For the subcortical structures:
- mild atrophy of the left pallidum; the right pallidum is normal
- no observable atrophic changes in the thalamus
- mild atrophy of the left hippocampus
- moderate-to-severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
- the caudate shows no notable changes suggestive of atrophy
- moderate bilateral atrophy of the accumbens
- mild-to-moderate atrophy of the left putamen; the right putamen is normal
For the ventricles:
- mild enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
- moderate enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- no evident size increase noted in the 4th ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a female of 54.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 7.
- On the semantic categorical fluency test, the subject named 10 animals in 60 seconds. She named 6 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 28, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 105, her number of commission errors is 1, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in disinhibition, a mild (noticeable, but not significant) change in agitation or aggression, elation or euphoria, apathy or indifference, irritability or lability, motor disturbance.
|
FTLD_203282633_03338_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10450581
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- moderate atrophy of the left caudate; the right caudate is normal
- mild atrophy of the left pallidum; the right pallidum is normal
- moderate-to-severe atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- moderate atrophy of the left putamen and mild atrophy of the right putamen
- severe bilateral atrophy of the amygdala
- thalamus appears preserved, with no observable tissue loss
For the cerebral cortex:
- no clear atrophic alterations are visible in the parietal lobe
- mild-to-moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild atrophy on the right) and posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right)
- the frontal lobe shows no notable changes suggestive of atrophy
- occipital lobe maintains a normal appearance with no observable atrophic features
- severe atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: fusiform gyrus (moderate atrophy on the left and mild atrophy on the right), temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and normal on the right), middle temporal gyrus (moderate atrophy on the left) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- moderate atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left) and middle cingulate gyrus (mild atrophy on the left and normal on the right)
For the ventricles:
- no clear enlargement or abnormal growth seen in the 4th ventricle
- mild enlargement of the external csf
- moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- moderate enlargement of the 3rd ventricle
- severe bilateral enlargement of the inf. lateral ventricle
|
SV
|
We have the following subject's personal information:
- The subject is a male of 70.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 0.
- On the semantic categorical fluency test, the subject named 0 animals in 60 seconds. He named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 3.
- On the Trail Making Test Part A, his total number of seconds to complete is 43, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 1, his number of correct lines is 13.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria, anxiety, disinhibition, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 10.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203188503_03308_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176913
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears to be of normal dimensions, with no observable increase in size
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- no observable enlargement of the 4th ventricle
- moderate enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- severe bilateral enlargement of the inf. lateral ventricle
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- the insular cortex shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left occipital lobe; normal-to-mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and mild-to-moderate atrophy on the right), inf. occipital gyrus (mild atrophy on the left and normal on the right) and occipital pole (mild atrophy on the left and normal on the right)
- mild atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy both left/right) and transverse temporal gyrus (mild atrophy on the left and normal on the right)
- the limbic cortex shows no notable changes suggestive of atrophy
- parietal lobe appears preserved, with no observable tissue loss
For the subcortical structures:
- no observable atrophic changes in the putamen
- mild atrophy of the right thalamus; normal-to-mild atrophy of the left thalamus
- moderate-to-severe atrophy of the left amygdala and severe atrophy of the right amygdala
- caudate appears within normal limits without apparent atrophy
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- moderate atrophy of the left hippocampus
- moderate atrophy of the right hippocampus
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
|
BV
|
We have the following subject's personal information:
- The subject is a male of 74.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 24.
- On the semantic categorical fluency test, the subject named 9 animals in 60 seconds. He named 8 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 75, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 179, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in disinhibition, a moderate (significant, but not dramatic) change in delusions, agitation or aggression, depression or dysphoria, a mild (noticeable, but not significant) change in anxiety, apathy or indifference, irritability or lability, motor disturbance, nighttime behaviors.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 9.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
|
FTLD_203881936_01638_MR_Sagittal_MP-Rage_br_raw_20230206145513748_I10181276
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- pallidum demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the putamen
- no appreciable degenerative or atrophic changes observed in the accumbens
- the caudate shows no notable changes suggestive of atrophy
- thalamus appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the amygdala
- hippocampus appears within normal limits without apparent atrophy
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- insular cortex appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the temporal lobe
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- frontal lobe appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the limbic cortex
For the ventricles:
- moderate enlargement of the 4th ventricle
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- no appreciable enlargement noted in the lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
- no appreciable enlargement noted in the 3rd ventricle
|
CN
|
We have the following subject's personal information:
- The subject is a male of 50.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 28 animals in 60 seconds. He named 17 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 22.
- On the Number Span forward test, his longest span forward was 8. On the Number Span backward test, his longest span backward was 6.
- On the Trail Making Test Part A, his total number of seconds to complete is 24, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 60, his number of commission errors is 0, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203755647_02745_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178297
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no clear atrophic alterations are visible in the parietal lobe
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), supplementary motor cortex (normal on the left and mild atrophy on the right) and subcallosal area (normal on the left and mild atrophy on the right)
- mild atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (normal on the left and moderate atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (normal on the left and mild-to-moderate atrophy on the right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- occipital lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right)
For the subcortical structures:
- mild-to-moderate atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- mild atrophy of the left putamen and moderate atrophy of the right putamen
- no evident atrophy or tissue thinning seen in the thalamus
- mild bilateral atrophy of the caudate
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- severe bilateral atrophy of the amygdala
- mild atrophy of the right pallidum; the left pallidum is normal
For the ventricles:
- mild enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- moderate bilateral enlargement of the lateral ventricle
- moderate enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a female of 64.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 27.
- On the semantic categorical fluency test, the subject named 27 animals in 60 seconds. She named 15 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 7.
- On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 53, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 89, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in irritability or lability, a moderate (significant, but not dramatic) change in anxiety, disinhibition, a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, apathy or indifference.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203212277_03771_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10451144
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- mild atrophy of the left caudate; the right caudate is normal
- no findings suggestive of atrophy are seen in the thalamus
- putamen appears preserved, with no observable tissue loss
- severe atrophy of the left amygdala and moderate atrophy of the right amygdala
- pallidum appears preserved, with no observable tissue loss
- severe atrophy of the left hippocampus
For the cerebral cortex:
- moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and normal-to-mild atrophy on the right), parahippocampal gyrus (mild atrophy both left/right), anterior cingulate gyrus (mild atrophy on the left) and posterior cingulate gyrus (mild atrophy on the left and normal on the right)
- no evident atrophy or tissue thinning seen in the frontal lobe
- no findings suggestive of atrophy are seen in the occipital lobe
- moderate atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right) and anterior insula (moderate-to-severe atrophy on the left and normal on the right)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: middle temporal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), temporal pole (moderate atrophy on the left and normal on the right), inf. temporal gyrus (moderate atrophy on the left) and fusiform gyrus (mild-to-moderate atrophy on the left and normal on the right)
For the ventricles:
- severe enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
- no evident size increase noted in the 4th ventricle
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- mild enlargement of the 3rd ventricle
- no findings suggestive of enlargement are seen in the external csf
|
SV
|
We have the following subject's personal information:
- The subject is a female of 56.0 years old.
- She has 12.0 years of education (equivalent to high school or GRE)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 0.
- On the semantic categorical fluency test, the subject named 3 animals in 60 seconds. She named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 4. On the Number Span backward test, her longest span backward was 6.
- On the Trail Making Test Part A, her total number of seconds to complete is 63, her number of commission errors is 1, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 300, her number of commission errors is 3, her number of correct lines is 16.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in appetite and eating.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on language, corresponding to mild impairment.
|
FTLD_203718156_02651_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177774
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the thalamus
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- no findings suggestive of atrophy are seen in the putamen
- no evident atrophy or tissue thinning seen in the caudate
- early/mild-grade volumetric reduction of the left hippocampus
- mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- no clear atrophic alterations are visible in the pallidum
For the ventricles:
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- mild-to-moderate enlargement of the external csf
- no evident size increase noted in the 4th ventricle
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- lateral ventricle maintains a typical volume without observable enlargement
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the temporal lobe
- limbic cortex maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the occipital lobe
- no clear atrophic alterations are visible in the frontal lobe
- no clear atrophic alterations are visible in the insular cortex
- parietal lobe appears within normal limits without apparent atrophy
|
BV
|
We have the following subject's personal information:
- The subject is a female of 74.0 years old.
- She has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 28.
- On the semantic categorical fluency test, the subject named 13 animals in 60 seconds. She named 13 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 25.
- On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 29, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 98, her number of commission errors is 1, her number of correct lines is 24.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203755647_02745_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178297
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the right pallidum; the left pallidum is normal
- thalamus appears preserved, with no observable tissue loss
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- mild bilateral atrophy of the caudate
- mild atrophy of the left putamen and moderate atrophy of the right putamen
- mild-to-moderate atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
- severe bilateral atrophy of the amygdala
For the ventricles:
- mild-to-moderate enlargement of the 3rd ventricle
- moderate enlargement of the left inf. lateral ventricle and moderate-to-severe enlargement of the right inf. lateral ventricle
- mild enlargement of the external csf
- moderate bilateral enlargement of the lateral ventricle
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- occipital lobe appears preserved, with no observable tissue loss
- mild atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right) and posterior insula (normal on the left and mild-to-moderate atrophy on the right)
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and moderate atrophy on the right), parahippocampal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right) and anterior cingulate gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the left temporal lobe and moderate-to-severe atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and moderate-to-severe atrophy on the right), inf. temporal gyrus (normal on the left and moderate atrophy on the right), middle temporal gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (normal on the left and mild-to-moderate atrophy on the right), planum polare (normal-to-mild atrophy on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the right)
- mild atrophy of the right frontal lobe; the left frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild-to-moderate atrophy both left/right), posterior orbital gyrus (mild atrophy on the left and mild-to-moderate atrophy on the right), medial orbital gyrus (normal-to-mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right), sup. frontal gyrus medial segment (normal on the left and mild atrophy on the right), supplementary motor cortex (normal on the left and mild atrophy on the right) and subcallosal area (normal on the left and mild atrophy on the right)
|
BV
|
We have the following subject's personal information:
- The subject is a female of 64.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 27.
- On the semantic categorical fluency test, the subject named 27 animals in 60 seconds. She named 15 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 7.
- On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 53, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 89, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in irritability or lability, a moderate (significant, but not dramatic) change in anxiety, disinhibition, a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, apathy or indifference.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203859805_01505_MR_Sagittal_MP-Rage_br_raw_20230206172921852_I10182096
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- amygdala appears preserved, with no observable tissue loss
- moderate atrophy of the left thalamus and mild atrophy of the right thalamus
- no findings suggestive of atrophy are seen in the accumbens
- pallidum appears preserved, with no observable tissue loss
- no observable atrophic changes in the caudate
- mild atrophy of the right putamen; normal-to-mild atrophy of the left putamen
- the hippocampus shows no notable changes suggestive of atrophy
For the ventricles:
- no observable enlargement of the inf. lateral ventricle
- mild enlargement of the external csf
- the 4th ventricle shows no notable changes suggestive of enlargement
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- no clear enlargement or abnormal growth seen in the lateral ventricle
For the cerebral cortex:
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- mild atrophy of the left parietal lobe; normal-to-mild atrophy of the right parietal lobe; focal volume loss observed in the following subregions: angular gyrus (mild atrophy both left/right) and postcentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right)
- no observable atrophic changes in the limbic cortex
- frontal lobe appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- insular cortex appears within normal limits without apparent atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a male of 28.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 28.
- On the semantic categorical fluency test, the subject named 12 animals in 60 seconds. He named 13 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 7.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 3.
- On the Trail Making Test Part A, his total number of seconds to complete is 32, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 123, his number of commission errors is 1, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203723261_03162_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177101
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- 3rd ventricle maintains a typical volume without observable enlargement
- mild-to-moderate enlargement of the external csf
- severe bilateral enlargement of the inf. lateral ventricle
- severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- no observable enlargement of the 4th ventricle
For the subcortical structures:
- moderate atrophy of the left hippocampus
- moderate atrophy of the right hippocampus
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- thalamus appears preserved, with no observable tissue loss
- mild-to-moderate atrophy of the left caudate; the right caudate is normal
- moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- severe bilateral atrophy of the amygdala
- moderate atrophy of the left putamen and mild-to-moderate atrophy of the right putamen
For the cerebral cortex:
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right) and posterior insula (moderate atrophy on the left and mild-to-moderate atrophy on the right)
- mild atrophy of the left limbic cortex; normal-to-mild atrophy of the right limbic cortex; focal volume loss observed in the following subregions: entorhinal area (moderate atrophy on the left and mild-to-moderate atrophy on the right) and parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right)
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and normal on the right), triangular inf. frontal gyrus (mild atrophy on the right) and medial frontal cortex (mild atrophy on the left)
- the parietal lobe shows no notable changes suggestive of atrophy
- severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild-to-moderate atrophy on the right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (moderate atrophy on the left and normal on the right), planum polare (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild-to-moderate atrophy on the left)
- occipital lobe maintains a normal appearance with no observable atrophic features
|
SV
|
We have the following subject's personal information:
- The subject is a male of 68.0 years old.
- He has 20.0 years of education (equivalent to doctorate)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 0 animals in 60 seconds. He named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 6.
- On the Trail Making Test Part A, his total number of seconds to complete is 56, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 6, his number of correct lines is 16.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in motor disturbance, a moderate (significant, but not dramatic) change in apathy or indifference, nighttime behaviors, appetite and eating, a mild (noticeable, but not significant) change in agitation or aggression.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. His standard CDR sum of boxes is 9.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203794298_03899_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047963
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the caudate
- no appreciable degenerative or atrophic changes observed in the thalamus
- no clear atrophic alterations are visible in the hippocampus
- amygdala maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the accumbens
- no evident atrophy or tissue thinning seen in the putamen
- the pallidum shows no notable changes suggestive of atrophy
For the cerebral cortex:
- limbic cortex appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the occipital lobe
- no clear atrophic alterations are visible in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the frontal lobe
- no observable atrophic changes in the temporal lobe
- insular cortex appears preserved, with no observable tissue loss
For the ventricles:
- no appreciable enlargement noted in the external csf
- no clear enlargement or abnormal growth seen in the lateral ventricle
- 4th ventricle appears within normal size limits with no apparent enlargement
- no appreciable enlargement noted in the 3rd ventricle
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
|
CN
|
We have the following subject's personal information:
- The subject is a male of 50.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 19 animals in 60 seconds. He named 16 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 15.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 4.
- On the Trail Making Test Part A, his total number of seconds to complete is 23, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 77, his number of commission errors is 1, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203089629_02928_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177882
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the 4th ventricle
- mild enlargement of the external csf
- the 3rd ventricle shows no notable changes suggestive of enlargement
- moderate enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no appreciable enlargement noted in the lateral ventricle
For the cerebral cortex:
- moderate-to-severe atrophy of the left temporal lobe and mild-to-moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left/right), inf. temporal gyrus (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), fusiform gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (mild atrophy on the left and normal on the right) and planum polare (mild atrophy on the left)
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: entorhinal area (mild atrophy on the left and normal on the right) and parahippocampal gyrus (mild atrophy on the left)
- parietal lobe appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the frontal lobe
- insular cortex demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- the accumbens shows no notable changes suggestive of atrophy
- pallidum appears within normal limits without apparent atrophy
- mild-to-moderate atrophy of the left hippocampus
- no observable atrophic changes in the caudate
- severe atrophy of the left amygdala and mild-to-moderate atrophy of the right amygdala
- putamen demonstrates a healthy morphology without signs of atrophy
- thalamus appears preserved, with no observable tissue loss
|
SV
|
We have the following subject's personal information:
- The subject is a female of 66.0 years old.
- She has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 1.
- On the semantic categorical fluency test, the subject named 2 animals in 60 seconds. She named 2 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 2.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 4.
- On the Trail Making Test Part A, her total number of seconds to complete is 56, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 89, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in depression or dysphoria, appetite and eating, a mild (noticeable, but not significant) change in hallucinations, nighttime behaviors.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203046366_02664_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177221
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate-to-severe atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (moderate atrophy on the left and mild-to-moderate atrophy on the right), precentral gyrus (mild-to-moderate atrophy both left/right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), middle frontal gyrus (moderate atrophy on the left and normal-to-mild atrophy on the right), supplementary motor cortex (mild-to-moderate atrophy on the left and mild atrophy on the right), triangular inf. frontal gyrus (mild atrophy on the left and normal on the right) and medial frontal cortex (mild atrophy on the left)
- the temporal lobe shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the limbic cortex
- no evident atrophy or tissue thinning seen in the occipital lobe
- mild atrophy of the left parietal lobe; the right parietal lobe is normal; focal volume loss observed in the following subregions: precuneus (mild atrophy on the left and normal on the right)
- moderate-to-severe atrophy of the left insular cortex and mild-to-moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate-to-severe atrophy on the left and mild atrophy on the right), central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal operculum (mild-to-moderate atrophy on the left and mild atrophy on the right) and parietal operculum (mild atrophy on the left and normal on the right)
For the ventricles:
- moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
- no appreciable enlargement noted in the 4th ventricle
- severe enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- moderate enlargement of the 3rd ventricle
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the hippocampus
- moderate atrophy of the left putamen and mild atrophy of the right putamen
- moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- mild-to-moderate atrophy of the left thalamus and mild atrophy of the right thalamus
- mild bilateral atrophy of the amygdala
- mild atrophy of the left accumbens; the right accumbens is normal
- mild atrophy of the left pallidum; the right pallidum is normal
|
PNFA
|
We have the following subject's personal information:
- The subject is a female of 75.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in anxiety, a mild (noticeable, but not significant) change in depression or dysphoria, appetite and eating.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203491601_02109_MR_Sagittal_MP-Rage_br_raw_20230206184338857_I10182627
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- no clear enlargement or abnormal growth seen in the external csf
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
- the inf. lateral ventricle shows no notable changes suggestive of enlargement
- no findings suggestive of enlargement are seen in the 4th ventricle
For the subcortical structures:
- no findings suggestive of atrophy are seen in the thalamus
- putamen appears preserved, with no observable tissue loss
- caudate maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the accumbens
- no findings suggestive of atrophy are seen in the pallidum
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
- amygdala demonstrates a healthy morphology without signs of atrophy
For the cerebral cortex:
- mild atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right) and parietal operculum (mild atrophy on the left)
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- frontal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the temporal lobe
- no findings suggestive of atrophy are seen in the limbic cortex
- the occipital lobe shows no notable changes suggestive of atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a female of 35.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 25 animals in 60 seconds. She named 17 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 15.
- On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 20, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 40, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203055281_02185_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10449602
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- the parietal lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the frontal lobe
- no evident atrophy or tissue thinning seen in the occipital lobe
- temporal lobe maintains a normal appearance with no observable atrophic features
- no clear atrophic alterations are visible in the limbic cortex
- no observable atrophic changes in the insular cortex
For the ventricles:
- severe bilateral enlargement of the lateral ventricle
- no observable enlargement of the external csf
- 4th ventricle maintains its expected proportions without signs of enlargement
- moderate bilateral enlargement of the inf. lateral ventricle
- mild enlargement of the 3rd ventricle
For the subcortical structures:
- mild bilateral atrophy of the putamen
- hippocampus maintains a normal appearance with no observable atrophic features
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- no evident atrophy or tissue thinning seen in the caudate
- mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens
- amygdala demonstrates a healthy morphology without signs of atrophy
- thalamus maintains a normal appearance with no observable atrophic features
|
CN
|
We have the following subject's personal information:
- The subject is a female of 67.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 11 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 22.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 31, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 68, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in nighttime behaviors.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203228793_01392_MR_Sagittal_MP-Rage_br_raw_20230206141035979_I10181143
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- the hippocampus shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the putamen
- no findings suggestive of atrophy are seen in the amygdala
- no evident atrophy or tissue thinning seen in the pallidum
- no findings suggestive of atrophy are seen in the accumbens
- no findings suggestive of atrophy are seen in the thalamus
- no appreciable degenerative or atrophic changes observed in the caudate
For the ventricles:
- lateral ventricle maintains its expected proportions without signs of enlargement
- no appreciable enlargement noted in the 3rd ventricle
- mild enlargement of the 4th ventricle
- inf. lateral ventricle appears to be of normal dimensions, with no observable increase in size
- no appreciable enlargement noted in the external csf
For the cerebral cortex:
- temporal lobe appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the insular cortex
- no observable atrophic changes in the occipital lobe
- no findings suggestive of atrophy are seen in the frontal lobe
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no evident atrophy or tissue thinning seen in the limbic cortex
|
CN
|
We have the following subject's personal information:
- The subject is a female of 45.0 years old.
- She has 20.0 years of education (equivalent to doctorate)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 23 animals in 60 seconds. She named 15 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 19.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 6.
- On the Trail Making Test Part A, her total number of seconds to complete is 16, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 24, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203081387_02788_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177039
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no clear atrophic alterations are visible in the thalamus
- no observable atrophic changes in the putamen
- caudate appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the amygdala
- no clear atrophic alterations are visible in the accumbens
- no appreciable degenerative or atrophic changes observed in the pallidum
- no appreciable degenerative or atrophic changes observed in the hippocampus
For the cerebral cortex:
- temporal lobe appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the parietal lobe
- no evident atrophy or tissue thinning seen in the insular cortex
- no clear atrophic alterations are visible in the frontal lobe
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: posterior cingulate gyrus (normal-to-mild atrophy on the left and mild atrophy on the right)
- occipital lobe maintains a normal appearance with no observable atrophic features
For the ventricles:
- no clear enlargement or abnormal growth seen in the external csf
- no appreciable enlargement noted in the 3rd ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- no findings suggestive of enlargement are seen in the lateral ventricle
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
|
CN
|
We have the following subject's personal information:
- The subject is a female of 37.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria, anxiety, irritability or lability.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203300760_03060_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178272
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the left thalamus; the right thalamus is normal
- severe atrophy of the left amygdala; the right amygdala is normal
- mild atrophy of the left putamen; the right putamen is normal
- accumbens appears within normal limits without apparent atrophy
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- mild-to-moderate atrophy of the left hippocampus
- early/mild-grade volumetric reduction of the right hippocampus
- mild atrophy of the left caudate; the right caudate is normal
For the cerebral cortex:
- frontal lobe demonstrates a healthy morphology without signs of atrophy
- no clear atrophic alterations are visible in the insular cortex
- parietal lobe maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the occipital lobe
- moderate-to-severe atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right), fusiform gyrus (mild atrophy on the left), inf. temporal gyrus (mild atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- mild-to-moderate atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right), entorhinal area (mild atrophy on the left) and anterior cingulate gyrus (mild atrophy on the left)
For the ventricles:
- no appreciable enlargement noted in the 4th ventricle
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- severe enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- no appreciable enlargement noted in the 3rd ventricle
- moderate enlargement of the external csf
|
SV
|
We have the following subject's personal information:
- The subject is a male of 59.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 3.
- On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. He named 5 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 7.
- On the Number Span forward test, his longest span forward was 9. On the Number Span backward test, his longest span backward was 6.
- On the Trail Making Test Part A, his total number of seconds to complete is 24, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 82, his number of commission errors is 1, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, anxiety, apathy or indifference, irritability or lability, appetite and eating.
|
FTLD_203590286_02689_MR_Accelerated_Sagittal_IR-FSPGR_br_raw_202_I10176953
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no evident size increase noted in the lateral ventricle
- no clear enlargement or abnormal growth seen in the external csf
- 3rd ventricle maintains its expected proportions without signs of enlargement
- no findings suggestive of enlargement are seen in the 4th ventricle
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
For the cerebral cortex:
- no clear atrophic alterations are visible in the frontal lobe
- no appreciable degenerative or atrophic changes observed in the insular cortex
- occipital lobe appears within normal limits without apparent atrophy
- no observable atrophic changes in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and normal-to-mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- limbic cortex maintains a normal appearance with no observable atrophic features
For the subcortical structures:
- no findings suggestive of atrophy are seen in the pallidum
- thalamus appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the accumbens
- amygdala demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the putamen
- hippocampus demonstrates a healthy morphology without signs of atrophy
- mild bilateral atrophy of the caudate
|
PNFA
|
We have the following subject's personal information:
- The subject is a male of 57.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 29.
- On the semantic categorical fluency test, the subject named 14 animals in 60 seconds. He named 10 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 9.
- On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 4.
- On the Trail Making Test Part A, his total number of seconds to complete is 82, his number of commission errors is 1, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 239, his number of commission errors is 3, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria, anxiety, apathy or indifference, motor disturbance, nighttime behaviors.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
|
FTLD_203050269_02965_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10177377
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild atrophy of the right thalamus; the left thalamus is normal
- mild bilateral atrophy of the caudate
- the amygdala shows no notable changes suggestive of atrophy
- mild-to-moderate atrophy of the left accumbens and mild atrophy of the right accumbens
- early/mild-grade volumetric reduction of the left hippocampus
- early/mild-grade volumetric reduction of the right hippocampus
- mild bilateral atrophy of the putamen
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
For the cerebral cortex:
- frontal lobe appears preserved, with no observable tissue loss
- mild atrophy of the left limbic cortex; the right limbic cortex is normal; focal volume loss observed in the following subregions: parahippocampal gyrus (mild atrophy both left/right)
- occipital lobe appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the temporal lobe
- mild atrophy of the right insular cortex; normal-to-mild atrophy of the left insular cortex; focal volume loss observed in the following subregions: anterior insula (mild-to-moderate atrophy on the left and normal on the right)
- no clear atrophic alterations are visible in the parietal lobe
For the ventricles:
- no clear enlargement or abnormal growth seen in the external csf
- mild enlargement of the 4th ventricle
- moderate bilateral enlargement of the inf. lateral ventricle
- moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- moderate-to-severe enlargement of the 3rd ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a male of 69.0 years old.
- He has 14.0 years of education
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 9 animals in 60 seconds. He named 3 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 17.
- On the Number Span forward test, his longest span forward was 5. On the Number Span backward test, his longest span backward was 4.
- On the Trail Making Test Part A, his total number of seconds to complete is 44, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 2, his number of correct lines is 23.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in nighttime behaviors, a moderate (significant, but not dramatic) change in apathy or indifference, disinhibition, irritability or lability, a mild (noticeable, but not significant) change in anxiety, elation or euphoria, appetite and eating.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203250302_03205_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178289
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild-to-moderate atrophy of the left insular cortex and moderate atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy on the left and severe atrophy on the right), frontal operculum (mild atrophy both left/right) and posterior insula (normal on the left and mild atrophy on the right)
- occipital lobe maintains a normal appearance with no observable atrophic features
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (normal on the left and mild-to-moderate atrophy on the right)
- moderate atrophy of the right frontal lobe; normal-to-mild atrophy of the left frontal lobe; focal volume loss observed in the following subregions: medial orbital gyrus (mild atrophy on the left and moderate atrophy on the right), posterior orbital gyrus (mild-to-moderate atrophy both left/right), triangular inf. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy both left/right), opercular inf. frontal gyrus (mild-to-moderate atrophy on the right), orbital inf. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (normal-to-mild atrophy on the left and mild atrophy on the right), gyrus rectus (normal on the left and mild atrophy on the right), middle frontal gyrus (normal on the left and mild atrophy on the right) and lateral orbital gyrus (normal on the left and mild atrophy on the right)
- no observable atrophic changes in the parietal lobe
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy on the left and moderate atrophy on the right) and entorhinal area (normal on the left and mild atrophy on the right)
For the subcortical structures:
- mild atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild atrophy of the right pallidum; the left pallidum is normal
- mild atrophy of the right amygdala; normal-to-mild atrophy of the left amygdala
- thalamus appears preserved, with no observable tissue loss
- mild bilateral atrophy of the putamen
- no observable atrophic changes in the hippocampus
- mild atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
For the ventricles:
- moderate enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- mild enlargement of the external csf
- mild enlargement of the 3rd ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- mild-to-moderate bilateral enlargement of the lateral ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a female of 57.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 28.
- On the semantic categorical fluency test, the subject named 20 animals in 60 seconds. She named 14 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 23.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 6.
- On the Trail Making Test Part A, her total number of seconds to complete is 49, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 72, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in elation or euphoria, a mild (noticeable, but not significant) change in apathy or indifference, motor disturbance.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203963723_01326_MR_Sagittal_MP-Rage_br_raw_20230206172100739_I10182036
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- thalamus appears within normal limits without apparent atrophy
- pallidum demonstrates a healthy morphology without signs of atrophy
- caudate demonstrates a healthy morphology without signs of atrophy
- putamen appears preserved, with no observable tissue loss
- no observable atrophic changes in the hippocampus
- no clear atrophic alterations are visible in the amygdala
- mild atrophy of the right accumbens; normal-to-mild atrophy of the left accumbens
For the cerebral cortex:
- limbic cortex appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the frontal lobe
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the insular cortex
- no clear atrophic alterations are visible in the temporal lobe
- no clear atrophic alterations are visible in the occipital lobe
For the ventricles:
- no evident size increase noted in the 3rd ventricle
- 4th ventricle maintains its expected proportions without signs of enlargement
- inf. lateral ventricle maintains a typical volume without observable enlargement
- no appreciable enlargement noted in the external csf
- lateral ventricle appears to be of normal dimensions, with no observable increase in size
|
CN
|
We have the following subject's personal information:
- The subject is a male of 47.0 years old.
- He has 17.0 years of education
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 26 animals in 60 seconds. He named 16 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 32.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 6.
- On the Trail Making Test Part A, his total number of seconds to complete is 23, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 45, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in anxiety.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203568133_01336_MR_Sagittal_MP-Rage_br_raw_20230206172305267_I10182049
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the 3rd ventricle
- severe enlargement of the left inf. lateral ventricle; normal-to-mild enlargement of the right inf. lateral ventricle
- moderate-to-severe enlargement of the left lateral ventricle and moderate enlargement of the right lateral ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- external csf maintains a typical volume without observable enlargement
For the cerebral cortex:
- moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: middle frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), frontal pole (mild atrophy both left/right), sup. frontal gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), lateral orbital gyrus (mild atrophy on the left and normal on the right), precentral gyrus (mild atrophy on the left and normal on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right), precentral gyrus medial segment (mild atrophy on the left and normal on the right) and supplementary motor cortex (normal on the left and mild atrophy on the right)
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left insular cortex; the right insular cortex is normal; focal volume loss observed in the following subregions: frontal operculum (mild atrophy on the left and normal on the right)
- no findings suggestive of atrophy are seen in the parietal lobe
- the limbic cortex shows no notable changes suggestive of atrophy
- the occipital lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- no clear atrophic alterations are visible in the amygdala
- mild-to-moderate atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- mild atrophy of the left hippocampus
- mild atrophy of the left thalamus; the right thalamus is normal
- mild atrophy of the left putamen; normal-to-mild atrophy of the right putamen
- no observable atrophic changes in the accumbens
|
BV
|
We have the following subject's personal information:
- The subject is a male of 73.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 26.
- On the semantic categorical fluency test, the subject named 2 animals in 60 seconds. He named 2 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 3.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in apathy or indifference, disinhibition, appetite and eating, a moderate (significant, but not dramatic) change in motor disturbance, nighttime behaviors.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203701178_02870_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178101
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- the lateral ventricle shows no notable changes suggestive of enlargement
- the external csf shows no notable changes suggestive of enlargement
- 3rd ventricle maintains its expected proportions without signs of enlargement
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the insular cortex
- limbic cortex appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the temporal lobe
- no observable atrophic changes in the parietal lobe
- no evident atrophy or tissue thinning seen in the occipital lobe
- frontal lobe demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- no observable atrophic changes in the hippocampus
- no evident atrophy or tissue thinning seen in the accumbens
- amygdala appears preserved, with no observable tissue loss
- no findings suggestive of atrophy are seen in the caudate
- thalamus appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the pallidum
- no findings suggestive of atrophy are seen in the putamen
|
BV
|
We have the following subject's personal information:
- The subject is a male of 48.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 17 animals in 60 seconds. He named 10 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 10.
- On the Number Span forward test, his longest span forward was 5. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 120, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 240, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in irritability or lability, a moderate (significant, but not dramatic) change in agitation or aggression, depression or dysphoria, elation or euphoria, apathy or indifference, disinhibition, a mild (noticeable, but not significant) change in anxiety.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203626426_01622_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176859
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild-to-moderate enlargement of the external csf
- no evident size increase noted in the inf. lateral ventricle
- no appreciable enlargement noted in the 4th ventricle
- no evident size increase noted in the lateral ventricle
- 3rd ventricle appears within normal size limits with no apparent enlargement
For the cerebral cortex:
- the limbic cortex shows no notable changes suggestive of atrophy
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (normal-to-mild atrophy on the left and mild atrophy on the right)
- no clear atrophic alterations are visible in the parietal lobe
- the occipital lobe shows no notable changes suggestive of atrophy
- insular cortex appears preserved, with no observable tissue loss
- no observable atrophic changes in the frontal lobe
For the subcortical structures:
- amygdala appears preserved, with no observable tissue loss
- hippocampus appears within normal limits without apparent atrophy
- pallidum appears within normal limits without apparent atrophy
- mild atrophy of the left caudate; normal-to-mild atrophy of the right caudate
- putamen maintains a normal appearance with no observable atrophic features
- mild atrophy of the right thalamus; the left thalamus is normal
- accumbens appears within normal limits without apparent atrophy
|
BV
|
We have the following subject's personal information:
- The subject is a male of 80.0 years old.
- He has 20.0 years of education (equivalent to doctorate)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in irritability or lability, a moderate (significant, but not dramatic) change in agitation or aggression, apathy or indifference, disinhibition, nighttime behaviors.
- On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203275236_01637_MR_Sagittal_MP-Rage_br_raw_20230206145408204_I10181272
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the accumbens
- no clear atrophic alterations are visible in the caudate
- mild bilateral atrophy of the thalamus
- mild atrophy of the left amygdala; the right amygdala is normal
- mild atrophy of the right hippocampus
- no clear atrophic alterations are visible in the putamen
- no observable atrophic changes in the pallidum
For the cerebral cortex:
- mild atrophy of the right limbic cortex; the left limbic cortex is normal
- occipital lobe appears preserved, with no observable tissue loss
- no clear atrophic alterations are visible in the insular cortex
- the frontal lobe shows no notable changes suggestive of atrophy
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- no clear atrophic alterations are visible in the parietal lobe
For the ventricles:
- mild enlargement of the right lateral ventricle; the left lateral ventricle is normal
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- 3rd ventricle maintains a typical volume without observable enlargement
- mild enlargement of the external csf
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
|
CN
|
We have the following subject's personal information:
- The subject is a male of 51.0 years old.
- He has 20.0 years of education (equivalent to doctorate)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 25 animals in 60 seconds. He named 10 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 29.
- On the Number Span forward test, his longest span forward was 9. On the Number Span backward test, his longest span backward was 6.
- On the Trail Making Test Part A, his total number of seconds to complete is 24, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 43, his number of commission errors is 0, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203098865_03569_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450937
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the parietal lobe
- mild bilateral atrophy of the frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), posterior orbital gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and normal-to-mild atrophy on the right), orbital inf. frontal gyrus (normal on the left and mild atrophy on the right) and triangular inf. frontal gyrus (normal on the left and mild atrophy on the right)
- insular cortex maintains a normal appearance with no observable atrophic features
- mild atrophy of the right limbic cortex; the left limbic cortex is normal; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right) and entorhinal area (normal on the left and mild atrophy on the right)
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- no clear atrophic alterations are visible in the occipital lobe
For the subcortical structures:
- mild-to-moderate atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
- moderate atrophy of the left caudate and mild-to-moderate atrophy of the right caudate
- mild-to-moderate atrophy of the left pallidum and mild atrophy of the right pallidum
- moderate bilateral atrophy of the accumbens
- moderate bilateral atrophy of the putamen
- mild-to-moderate bilateral atrophy of the thalamus
- moderate atrophy of the left hippocampus
- moderate-to-severe atrophy of the right hippocampus
For the ventricles:
- mild enlargement of the external csf
- severe bilateral enlargement of the inf. lateral ventricle
- no appreciable enlargement noted in the 4th ventricle
- severe bilateral enlargement of the lateral ventricle
- moderate enlargement of the 3rd ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a male of 60.0 years old.
- He has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 29.
- On the semantic categorical fluency test, the subject named 8 animals in 60 seconds. He named 8 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 6. On the Number Span backward test, his longest span backward was 3.
- On the Trail Making Test Part A, his total number of seconds to complete is 66, his number of commission errors is 1, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in nighttime behaviors, a mild (noticeable, but not significant) change in apathy or indifference, disinhibition, irritability or lability, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 6.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203489181_03188_MR_Sagittal_3D_Accelerated_MPRAGE_br_raw_202_I10176905
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- mild-to-moderate enlargement of the 3rd ventricle
- the external csf shows no notable changes suggestive of enlargement
- mild enlargement of the 4th ventricle
- mild-to-moderate bilateral enlargement of the lateral ventricle
For the cerebral cortex:
- mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy both left/right), central operculum (normal on the left and mild atrophy on the right), posterior insula (normal on the left and mild atrophy on the right) and parietal operculum (mild atrophy on the left and normal on the right)
- the parietal lobe shows no notable changes suggestive of atrophy
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- no evident atrophy or tissue thinning seen in the frontal lobe
- temporal lobe demonstrates a healthy morphology without signs of atrophy
For the subcortical structures:
- no clear atrophic alterations are visible in the putamen
- no appreciable degenerative or atrophic changes observed in the hippocampus
- no evident atrophy or tissue thinning seen in the pallidum
- no observable atrophic changes in the caudate
- the amygdala shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the thalamus
- mild atrophy of the left accumbens; the right accumbens is normal
|
BV
|
We have the following subject's personal information:
- The subject is a female of 59.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 18 animals in 60 seconds. She named 10 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 6.
- On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 24, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 200, her number of commission errors is 2, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in agitation or aggression, anxiety, irritability or lability, a moderate (significant, but not dramatic) change in delusions, elation or euphoria, disinhibition, a mild (noticeable, but not significant) change in apathy or indifference.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. Her standard CDR sum of boxes is 4.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 1.0 on behavior, comportment, and personality, corresponding to mild impairment.
|
FTLD_203144923_03324_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178124
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the right temporal lobe; the left temporal lobe is normal; focal volume loss observed in the following subregions: temporal pole (mild atrophy both left/right) and fusiform gyrus (mild atrophy on the left and normal on the right)
- no appreciable degenerative or atrophic changes observed in the limbic cortex
- no clear atrophic alterations are visible in the occipital lobe
- mild-to-moderate atrophy of the left insular cortex; normal-to-mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and normal-to-mild atrophy on the right), posterior insula (mild atrophy on the left and normal on the right), frontal operculum (mild atrophy on the left and normal on the right) and parietal operculum (mild atrophy on the left)
- no findings suggestive of atrophy are seen in the frontal lobe
- the parietal lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- mild-to-moderate atrophy of the left amygdala and mild atrophy of the right amygdala
- mild atrophy of the left caudate; the right caudate is normal
- thalamus demonstrates a healthy morphology without signs of atrophy
- mild-to-moderate atrophy of the left putamen and mild atrophy of the right putamen
- the pallidum shows no notable changes suggestive of atrophy
- mild bilateral atrophy of the accumbens
- moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
For the ventricles:
- moderate-to-severe enlargement of the left lateral ventricle and mild-to-moderate enlargement of the right lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
- mild enlargement of the external csf
- mild-to-moderate enlargement of the 3rd ventricle
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
|
BV
|
We have the following subject's personal information:
- The subject is a male of 58.0 years old.
- He has 15.0 years of education
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 21.
- On the semantic categorical fluency test, the subject named 7 animals in 60 seconds. He named 0 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 0. On the Number Span backward test, his longest span backward was 0.
- On the Trail Making Test Part A, his total number of seconds to complete is 74, his number of commission errors is 2, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in anxiety, a moderate (significant, but not dramatic) change in irritability or lability, nighttime behaviors, a mild (noticeable, but not significant) change in delusions, agitation or aggression, elation or euphoria, apathy or indifference, disinhibition, motor disturbance, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 7.0.
|
FTLD_203489655_01558_MR_Sagittal_MP-Rage_br_raw_20230206173253890_I10182123
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- moderate atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: gyrus rectus (mild atrophy on the left and mild-to-moderate atrophy on the right), sup. frontal gyrus medial segment (mild atrophy on the left and mild-to-moderate atrophy on the right), medial frontal cortex (mild atrophy both left/right), middle frontal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), sup. frontal gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), opercular inf. frontal gyrus (mild atrophy on the left and normal on the right) and lateral orbital gyrus (mild atrophy on the left and normal on the right)
- moderate atrophy of the left temporal lobe and mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (moderate atrophy both left/right), inf. temporal gyrus (mild-to-moderate atrophy on the left and normal-to-mild atrophy on the right), middle temporal gyrus (mild-to-moderate atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- no clear atrophic alterations are visible in the occipital lobe
- no observable atrophic changes in the parietal lobe
- moderate-to-severe atrophy of the left limbic cortex and mild-to-moderate atrophy of the right limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (moderate atrophy on the left and mild atrophy on the right), middle cingulate gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), entorhinal area (mild atrophy both left/right), parahippocampal gyrus (mild-to-moderate atrophy on the left and normal on the right) and posterior cingulate gyrus (mild atrophy on the left)
- mild-to-moderate bilateral atrophy of the insular cortex; focal volume loss observed in the following subregions: anterior insula (moderate atrophy both left/right), posterior insula (mild-to-moderate atrophy on the left and mild atrophy on the right) and frontal operculum (mild atrophy both left/right)
For the subcortical structures:
- moderate bilateral atrophy of the accumbens
- no findings suggestive of atrophy are seen in the pallidum
- moderate atrophy of the left putamen and mild atrophy of the right putamen
- severe atrophy of the left amygdala and moderate-to-severe atrophy of the right amygdala
- moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
- moderate bilateral atrophy of the caudate
- mild-to-moderate atrophy of the left thalamus; the right thalamus is normal
For the ventricles:
- severe enlargement of the left inf. lateral ventricle and moderate enlargement of the right inf. lateral ventricle
- moderate bilateral enlargement of the lateral ventricle
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- mild-to-moderate enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the external csf
|
BV
|
We have the following subject's personal information:
- The subject is a female of 65.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 4.
- On the semantic categorical fluency test, the subject named 5 animals in 60 seconds. She named 7 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, her longest span forward was 5. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 40, her number of commission errors is 1, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in anxiety, apathy or indifference, disinhibition, irritability or lability, nighttime behaviors, a moderate (significant, but not dramatic) change in appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. Her standard CDR sum of boxes is 12.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203679862_03267_MR_Accelerated_Sagittal_MPRAGE_br_raw_20240_I10450433
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the occipital lobe
- temporal lobe maintains a normal appearance with no observable atrophic features
- the insular cortex shows no notable changes suggestive of atrophy
- limbic cortex maintains a normal appearance with no observable atrophic features
- no findings suggestive of atrophy are seen in the parietal lobe
- the frontal lobe shows no notable changes suggestive of atrophy
For the subcortical structures:
- mild bilateral atrophy of the thalamus
- mild bilateral atrophy of the pallidum
- mild bilateral atrophy of the putamen
- accumbens appears preserved, with no observable tissue loss
- mild atrophy of the right hippocampus
- mild atrophy of the right amygdala; the left amygdala is normal
- caudate appears within normal limits without apparent atrophy
For the ventricles:
- mild enlargement of the right inf. lateral ventricle; the left inf. lateral ventricle is normal
- mild enlargement of the external csf
- 4th ventricle maintains a typical volume without observable enlargement
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- mild bilateral enlargement of the lateral ventricle
|
PNFA
|
We have the following subject's personal information:
- The subject is a male of 73.0 years old.
- He has 20.0 years of education (equivalent to doctorate)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 15 animals in 60 seconds. He named 11 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 14.
- On the Number Span forward test, his longest span forward was 5. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 35, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 56, his number of commission errors is 0, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a mild (noticeable, but not significant) change in depression or dysphoria, irritability or lability.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 1.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on behavior, comportment, and personality, corresponding to no impairment.
|
FTLD_203450073_01375_MR_Sagittal_MP-Rage_br_raw_20230206140627534_I10181131
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no evident size increase noted in the lateral ventricle
- the 4th ventricle shows no notable changes suggestive of enlargement
- no observable enlargement of the inf. lateral ventricle
- no observable enlargement of the 3rd ventricle
- external csf maintains a typical volume without observable enlargement
For the subcortical structures:
- the accumbens shows no notable changes suggestive of atrophy
- amygdala maintains a normal appearance with no observable atrophic features
- putamen maintains a normal appearance with no observable atrophic features
- no appreciable degenerative or atrophic changes observed in the pallidum
- no observable atrophic changes in the caudate
- no evident atrophy or tissue thinning seen in the hippocampus
- mild atrophy of the left thalamus; the right thalamus is normal
For the cerebral cortex:
- no evident atrophy or tissue thinning seen in the insular cortex
- no observable atrophic changes in the occipital lobe
- mild atrophy of the left temporal lobe; normal-to-mild atrophy of the right temporal lobe; focal volume loss observed in the following subregions: planum temporale (mild-to-moderate atrophy on the left and normal on the right), temporal pole (normal on the left and mild atrophy on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no clear atrophic alterations are visible in the limbic cortex
- no evident atrophy or tissue thinning seen in the frontal lobe
|
CN
|
We have the following subject's personal information:
- The subject is a female of 54.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 40 animals in 60 seconds. She named 27 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 22.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 21, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 57, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203575598_02897_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177141
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- no findings suggestive of atrophy are seen in the pallidum
- caudate appears within normal limits without apparent atrophy
- putamen appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the accumbens
- hippocampus appears within normal limits without apparent atrophy
- amygdala demonstrates a healthy morphology without signs of atrophy
- no findings suggestive of atrophy are seen in the thalamus
For the ventricles:
- 4th ventricle appears within normal size limits with no apparent enlargement
- 3rd ventricle appears within normal size limits with no apparent enlargement
- no findings suggestive of enlargement are seen in the inf. lateral ventricle
- no findings suggestive of enlargement are seen in the lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
For the cerebral cortex:
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- no observable atrophic changes in the insular cortex
- no observable atrophic changes in the temporal lobe
- no findings suggestive of atrophy are seen in the limbic cortex
- no clear atrophic alterations are visible in the occipital lobe
- no appreciable degenerative or atrophic changes observed in the frontal lobe
|
CN
|
We have the following subject's personal information:
- The subject is a female of 44.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 24 animals in 60 seconds. She named 17 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 22.
- On the Number Span forward test, her longest span forward was 7. On the Number Span backward test, her longest span backward was 3.
- On the Trail Making Test Part A, her total number of seconds to complete is 28, her number of commission errors is 1, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 68, her number of commission errors is 2, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in nighttime behaviors.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203856309_03905_MR_Accelerated_Sagittal_MPRAGE_br_raw_20241_I11047976
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- severe enlargement of the left lateral ventricle and moderate-to-severe enlargement of the right lateral ventricle
- 4th ventricle maintains a typical volume without observable enlargement
- moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- moderate enlargement of the external csf
- mild enlargement of the 3rd ventricle
For the subcortical structures:
- severe atrophy of the left putamen and moderate-to-severe atrophy of the right putamen
- moderate-to-severe atrophy of the left caudate and moderate atrophy of the right caudate
- mild-to-moderate bilateral atrophy of the pallidum
- mild-to-moderate atrophy of the left accumbens and moderate atrophy of the right accumbens
- moderate bilateral atrophy of the amygdala
- thalamus appears preserved, with no observable tissue loss
- mild-to-moderate atrophy of the left hippocampus
- mild-to-moderate atrophy of the right hippocampus
For the cerebral cortex:
- mild bilateral atrophy of the parietal lobe; focal volume loss observed in the following subregions: postcentral gyrus (normal on the left and mild atrophy on the right)
- mild-to-moderate atrophy of the left frontal lobe and mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild-to-moderate atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy both left/right), medial frontal cortex (normal on the left and mild-to-moderate atrophy on the right), precentral gyrus medial segment (normal-to-mild atrophy on the left and mild atrophy on the right) and gyrus rectus (mild atrophy on the left and normal on the right)
- mild bilateral atrophy of the limbic cortex; focal volume loss observed in the following subregions: anterior cingulate gyrus (mild atrophy both left/right), parahippocampal gyrus (mild atrophy on the left and normal on the right) and posterior cingulate gyrus (mild atrophy on the left and normal on the right)
- mild-to-moderate atrophy of the left insular cortex and mild atrophy of the right insular cortex; focal volume loss observed in the following subregions: central operculum (mild-to-moderate atrophy on the left and mild atrophy on the right), parietal operculum (mild atrophy both left/right), posterior insula (normal on the left and mild-to-moderate atrophy on the right) and anterior insula (mild atrophy on the left and normal on the right)
- moderate bilateral atrophy of the temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild-to-moderate atrophy on the left and mild atrophy on the right), middle temporal gyrus (mild atrophy both left/right), fusiform gyrus (normal-to-mild atrophy on the left and mild atrophy on the right), planum temporale (mild atrophy on the left and normal-to-mild atrophy on the right), sup. temporal gyrus (normal on the left and mild atrophy on the right), transverse temporal gyrus (mild atrophy on the left and normal on the right) and planum polare (normal on the left and mild atrophy on the right)
- occipital lobe appears within normal limits without apparent atrophy
|
BV
|
We have the following subject's personal information:
- The subject is a female of 52.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is left-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 17.
- On the semantic categorical fluency test, the subject named 8 animals in 60 seconds. She named 4 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 7.
- On the Trail Making Test Part A, her total number of seconds to complete is 87, her number of commission errors is 0, her number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in agitation or aggression, apathy or indifference, disinhibition, irritability or lability, motor disturbance, nighttime behaviors, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 2.0, corresponding to moderate impairment. Her standard CDR sum of boxes is 9.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 2.0 on language, corresponding to moderate impairment.
|
FTLD_203100315_01510_MR_Sagittal_MP-Rage_br_raw_20230124211509176_I10178577
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- external csf appears to be of normal dimensions, with no observable increase in size
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- the 4th ventricle shows no notable changes suggestive of enlargement
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- mild enlargement of the left lateral ventricle; normal-to-mild enlargement of the right lateral ventricle
For the subcortical structures:
- the thalamus shows no notable changes suggestive of atrophy
- hippocampus appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the putamen
- no clear atrophic alterations are visible in the caudate
- mild atrophy of the left accumbens; the right accumbens is normal
- the amygdala shows no notable changes suggestive of atrophy
- the pallidum shows no notable changes suggestive of atrophy
For the cerebral cortex:
- frontal lobe appears preserved, with no observable tissue loss
- insular cortex demonstrates a healthy morphology without signs of atrophy
- the parietal lobe shows no notable changes suggestive of atrophy
- temporal lobe appears within normal limits without apparent atrophy
- no evident atrophy or tissue thinning seen in the limbic cortex
- mild atrophy of the left occipital lobe; normal-to-mild atrophy of the right occipital lobe; focal volume loss observed in the following subregions: calcarine cortex (mild atrophy on the left and normal on the right)
|
CN
|
We have the following subject's personal information:
- The subject is a female of 63.0 years old.
- She has 15.0 years of education
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 24 animals in 60 seconds. She named 14 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 24.
- On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 6.
- On the Trail Making Test Part A, her total number of seconds to complete is 18, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 38, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203287150_02058_MR_Sagittal_MP-Rage_br_raw_20230206130349641_I10180917
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- putamen maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the hippocampus
- amygdala demonstrates a healthy morphology without signs of atrophy
- no appreciable degenerative or atrophic changes observed in the caudate
- thalamus appears within normal limits without apparent atrophy
- no findings suggestive of atrophy are seen in the pallidum
- accumbens maintains a normal appearance with no observable atrophic features
For the cerebral cortex:
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: central operculum (normal on the left and mild atrophy on the right)
- frontal lobe appears preserved, with no observable tissue loss
- mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: cuneus (mild atrophy both left/right)
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the limbic cortex
For the ventricles:
- no evident size increase noted in the lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
- no clear enlargement or abnormal growth seen in the 3rd ventricle
- no observable enlargement of the inf. lateral ventricle
- no clear enlargement or abnormal growth seen in the 4th ventricle
|
CN
|
We have the following subject's personal information:
- The subject is a female of 34.0 years old.
- She has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 30.
- On the semantic categorical fluency test, the subject named 33 animals in 60 seconds. She named 16 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 27.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 4.
- On the Trail Making Test Part A, her total number of seconds to complete is 20, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 42, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203767384_02486_MR_Sagittal_MP-Rage_br_raw_20230124213136983_I10178672
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- limbic cortex appears within normal limits without apparent atrophy
- no appreciable degenerative or atrophic changes observed in the parietal lobe
- no appreciable degenerative or atrophic changes observed in the temporal lobe
- mild atrophy of the right occipital lobe; the left occipital lobe is normal; focal volume loss observed in the following subregions: inf. occipital gyrus (normal-to-mild atrophy on the left and mild atrophy on the right) and middle occipital gyrus (mild atrophy on the left and normal on the right)
- no observable atrophic changes in the insular cortex
- the frontal lobe shows no notable changes suggestive of atrophy
For the ventricles:
- mild enlargement of the left inf. lateral ventricle; the right inf. lateral ventricle is normal
- no clear enlargement or abnormal growth seen in the external csf
- mild enlargement of the left lateral ventricle; the right lateral ventricle is normal
- 4th ventricle appears to be of normal dimensions, with no observable increase in size
- no findings suggestive of enlargement are seen in the 3rd ventricle
For the subcortical structures:
- caudate appears within normal limits without apparent atrophy
- hippocampus demonstrates a healthy morphology without signs of atrophy
- pallidum maintains a normal appearance with no observable atrophic features
- no evident atrophy or tissue thinning seen in the thalamus
- no observable atrophic changes in the putamen
- accumbens appears preserved, with no observable tissue loss
- amygdala appears within normal limits without apparent atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a female of 75.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 28.
- On the semantic categorical fluency test, the subject named 17 animals in 60 seconds. She named 14 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 12.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 34, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 92, her number of commission errors is 1, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203215986_02681_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10178194
|
On a T1-weighted brain MRI we observed:
For the cerebral cortex:
- mild atrophy of the left temporal lobe; the right temporal lobe is normal; focal volume loss observed in the following subregions: planum temporale (mild atrophy on the left and normal on the right) and sup. temporal gyrus (mild atrophy on the left and normal on the right)
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- insular cortex maintains a normal appearance with no observable atrophic features
- mild atrophy of the left frontal lobe; the right frontal lobe is normal; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy both left/right), frontal pole (normal-to-mild atrophy on the left and mild atrophy on the right), precentral gyrus (mild atrophy on the left and normal-to-mild atrophy on the right), anterior orbital gyrus (mild atrophy on the left and normal on the right), triangular inf. frontal gyrus (mild atrophy on the left) and lateral orbital gyrus (mild atrophy on the right)
- no observable atrophic changes in the limbic cortex
- no clear atrophic alterations are visible in the occipital lobe
For the ventricles:
- mild-to-moderate enlargement of the left inf. lateral ventricle and mild enlargement of the right inf. lateral ventricle
- mild-to-moderate enlargement of the external csf
- 4th ventricle maintains a typical volume without observable enlargement
- mild-to-moderate enlargement of the 3rd ventricle
- no clear enlargement or abnormal growth seen in the lateral ventricle
For the subcortical structures:
- mild atrophy of the left putamen; the right putamen is normal
- mild bilateral atrophy of the caudate
- mild atrophy of the right accumbens; the left accumbens is normal
- mild atrophy of the left thalamus; the right thalamus is normal
- mild-to-moderate atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- mild atrophy of the left pallidum; normal-to-mild atrophy of the right pallidum
- mild atrophy of the left hippocampus
- mild atrophy of the right hippocampus
|
BV
|
We have the following subject's personal information:
- The subject is a male of 65.0 years old.
- He has 16.0 years of education (equivalent to bachelor’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 23.
- On the semantic categorical fluency test, the subject named 4 animals in 60 seconds. He named 3 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 0.
- On the Number Span forward test, his longest span forward was 4. On the Number Span backward test, his longest span backward was 2.
- On the Trail Making Test Part A, his total number of seconds to complete is 136, his number of commission errors is 1, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 300, his number of commission errors is 3, his number of correct lines is 10.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a moderate (significant, but not dramatic) change in irritability or lability, motor disturbance, a mild (noticeable, but not significant) change in agitation or aggression, depression or dysphoria, anxiety, appetite and eating.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment
|
FTLD_203244547_01744_MR_Sagittal_MP-Rage_br_raw_20230124205159364_I10178413
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- no clear enlargement or abnormal growth seen in the lateral ventricle
- the external csf shows no notable changes suggestive of enlargement
- 3rd ventricle appears to be of normal dimensions, with no observable increase in size
- no observable enlargement of the 4th ventricle
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
For the cerebral cortex:
- no observable atrophic changes in the frontal lobe
- temporal lobe appears preserved, with no observable tissue loss
- no observable atrophic changes in the parietal lobe
- the insular cortex shows no notable changes suggestive of atrophy
- no findings suggestive of atrophy are seen in the occipital lobe
- limbic cortex appears within normal limits without apparent atrophy
For the subcortical structures:
- no evident atrophy or tissue thinning seen in the accumbens
- putamen demonstrates a healthy morphology without signs of atrophy
- mild atrophy of the left amygdala; normal-to-mild atrophy of the right amygdala
- thalamus appears preserved, with no observable tissue loss
- no evident atrophy or tissue thinning seen in the caudate
- no findings suggestive of atrophy are seen in the pallidum
- hippocampus appears preserved, with no observable tissue loss
|
CN
|
We have the following subject's personal information:
- The subject is a female of 59.0 years old.
- She has 12.0 years of education (equivalent to high school or GRE)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 27.
- On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 13 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 28.
- On the Number Span forward test, her longest span forward was 6. On the Number Span backward test, her longest span backward was 6.
- On the Trail Making Test Part A, her total number of seconds to complete is 21, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 54, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203655682_01285_MR_Sagittal_MP-Rage_br_raw_20230206171215135_I10181970
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- hippocampus appears preserved, with no observable tissue loss
- putamen appears within normal limits without apparent atrophy
- thalamus appears within normal limits without apparent atrophy
- amygdala maintains a normal appearance with no observable atrophic features
- pallidum demonstrates a healthy morphology without signs of atrophy
- accumbens appears preserved, with no observable tissue loss
- no appreciable degenerative or atrophic changes observed in the caudate
For the ventricles:
- 3rd ventricle maintains a typical volume without observable enlargement
- no appreciable enlargement noted in the external csf
- no evident size increase noted in the 4th ventricle
- no evident size increase noted in the lateral ventricle
- no clear enlargement or abnormal growth seen in the inf. lateral ventricle
For the cerebral cortex:
- occipital lobe demonstrates a healthy morphology without signs of atrophy
- limbic cortex demonstrates a healthy morphology without signs of atrophy
- frontal lobe appears within normal limits without apparent atrophy
- temporal lobe demonstrates a healthy morphology without signs of atrophy
- insular cortex maintains a normal appearance with no observable atrophic features
- parietal lobe appears within normal limits without apparent atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a male of 73.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 28 animals in 60 seconds. He named 17 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 29.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 21, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 44, his number of commission errors is 0, his number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. His standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203138707_01703_MR_Sagittal_MP-Rage_br_raw_20230124212017175_I10178606
|
On a T1-weighted brain MRI we observed:
For the ventricles:
- lateral ventricle appears within normal size limits with no apparent enlargement
- inf. lateral ventricle appears within normal size limits with no apparent enlargement
- no appreciable enlargement noted in the 3rd ventricle
- external csf maintains its expected proportions without signs of enlargement
- no appreciable enlargement noted in the 4th ventricle
For the subcortical structures:
- no appreciable degenerative or atrophic changes observed in the hippocampus
- no appreciable degenerative or atrophic changes observed in the accumbens
- no findings suggestive of atrophy are seen in the caudate
- no evident atrophy or tissue thinning seen in the thalamus
- the amygdala shows no notable changes suggestive of atrophy
- putamen appears within normal limits without apparent atrophy
- the pallidum shows no notable changes suggestive of atrophy
For the cerebral cortex:
- no findings suggestive of atrophy are seen in the insular cortex
- parietal lobe demonstrates a healthy morphology without signs of atrophy
- the temporal lobe shows no notable changes suggestive of atrophy
- no clear atrophic alterations are visible in the limbic cortex
- mild atrophy of the left frontal lobe; normal-to-mild atrophy of the right frontal lobe; focal volume loss observed in the following subregions: lateral orbital gyrus (mild atrophy both left/right), subcallosal area (mild atrophy both left/right), frontal pole (normal on the left and mild atrophy on the right), supplementary motor cortex (mild atrophy on the left and normal on the right), sup. frontal gyrus (normal on the left and mild atrophy on the right) and middle frontal gyrus (mild atrophy on the left and normal on the right)
- occipital lobe appears within normal limits without apparent atrophy
|
CN
|
We have the following subject's personal information:
- The subject is a female of 49.0 years old.
- She has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- On the semantic categorical fluency test, the subject named 21 animals in 60 seconds. She named 15 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, her total story units recalled (verbatim scoring) is 23.
- On the Number Span forward test, her longest span forward was 8. On the Number Span backward test, her longest span backward was 5.
- On the Trail Making Test Part A, her total number of seconds to complete is 28, her number of commission errors is 0, her number of correct lines is 24. On the Trail Making Test Part B, her total number of seconds to complete is 48, her number of commission errors is 0, her number of correct lines is 24.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 0.0, corresponding to no impairment. Her standard CDR sum of boxes is 0.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
FTLD_203192236_02639_MR_Accelerated_Sagittal_MPRAGE_br_raw_20230_I10177752
|
On a T1-weighted brain MRI we observed:
For the subcortical structures:
- mild bilateral atrophy of the pallidum
- mild atrophy of the left thalamus and mild-to-moderate atrophy of the right thalamus
- moderate bilateral atrophy of the amygdala
- moderate atrophy of the left hippocampus
- moderate atrophy of the right hippocampus
- moderate atrophy of the left accumbens and mild-to-moderate atrophy of the right accumbens
- mild-to-moderate bilateral atrophy of the putamen
- mild-to-moderate atrophy of the left caudate and moderate atrophy of the right caudate
For the ventricles:
- severe bilateral enlargement of the inf. lateral ventricle
- severe enlargement of the 3rd ventricle
- mild-to-moderate enlargement of the external csf
- mild bilateral enlargement of the lateral ventricle
- no findings suggestive of enlargement are seen in the 4th ventricle
For the cerebral cortex:
- mild atrophy of the right insular cortex; the left insular cortex is normal; focal volume loss observed in the following subregions: anterior insula (mild atrophy on the left and mild-to-moderate atrophy on the right)
- limbic cortex appears within normal limits without apparent atrophy
- parietal lobe appears within normal limits without apparent atrophy
- mild atrophy of the left temporal lobe and moderate atrophy of the right temporal lobe; focal volume loss observed in the following subregions: temporal pole (mild atrophy on the left and mild-to-moderate atrophy on the right), fusiform gyrus (mild atrophy both left/right), middle temporal gyrus (normal on the left and mild atrophy on the right) and inf. temporal gyrus (normal on the left and mild atrophy on the right)
- mild atrophy of the left frontal lobe and mild-to-moderate atrophy of the right frontal lobe; focal volume loss observed in the following subregions: sup. frontal gyrus (mild atrophy both left/right), gyrus rectus (normal-to-mild atrophy on the left and mild atrophy on the right), medial frontal cortex (mild atrophy on the left and normal on the right) and middle frontal gyrus (normal on the left and mild atrophy on the right)
- the occipital lobe shows no notable changes suggestive of atrophy
|
BV
|
We have the following subject's personal information:
- The subject is a male of 64.0 years old.
- He has 18.0 years of education (equivalent to master’s degree)
- The subject is right-handed
We have the following results on the Neuropsychological Test Battery:
- The subject has a 32-item Multilingual Naming Test (MINT) total score of 22.
- On the semantic categorical fluency test, the subject named 2 animals in 60 seconds. He named 3 vegetables in 60 seconds.
- On the Craft Story 21 Recall (Delayed) test, his total story units recalled (verbatim scoring) is 8.
- On the Number Span forward test, his longest span forward was 7. On the Number Span backward test, his longest span backward was 5.
- On the Trail Making Test Part A, his total number of seconds to complete is 68, his number of commission errors is 0, his number of correct lines is 24. On the Trail Making Test Part B, his total number of seconds to complete is 187, his number of commission errors is 2, his number of correct lines is 24.
- In the Neuropsychiatric Inventory Questionnaire (NPI-Q), in the last month, the clinician notes a severe (very marked or prominent, dramatic) change in appetite and eating, a moderate (significant, but not dramatic) change in apathy or indifference, nighttime behaviors.
- With the CDR Dementia Staging Instrument (CDR), the subject has a global score of 1.0, corresponding to mild impairment. His standard CDR sum of boxes is 5.0. On CDR Dementia Staging Instrument PLUS National Alzheimer’s Coordinating Center (NACC), the subject has a score of 0.0 on language, corresponding to no impairment.
|
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