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Bydureon BCise

Generic Name: exenatide (Bydureon) (ex EN a tide)
Brand Name: Bydureon BCise, Bydureon Pen, Bydureon Tray

Medically reviewed by on Jun 3, 2018 – Written by Cerner Multum

What is Bydureon BCise (Bydureon)?

This medication guide provides information about the Bydureon brand of exenatide. Byetta is another brand of exenatide that is not covered in this medication guide.

Bydureon BCise is an injectable diabetes medicine that helps control blood sugar levels. This medication helps your pancreas produce insulin more efficiently. Bydureon is a long-acting form of exenatide.

Bydureon is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Bydureon is not for treating type 1 diabetes.

Bydureon may also be used for purposes not listed in this medication guide.

Important Information

You should not use Bydureon BCise if you have severe kidney disease (or you are on dialysis), slowed digestion, diabetic ketoacidosis, a personal or family history of thyroid cancer, or if you have a type of cancer called multiple endocrine neoplasia type 2 (MEN 2).

Before taking this medicine

You should not use this medicine if you are allergic to Bydureon BCise, or if you have:


  • a severe stomach disorder that causes slow digestion; or


You should not use Bydureon if you have a personal or family history of thyroid cancer, or if you have multiple endocrine neoplasia type 2 (MEN 2, a cancer that can affect the thyroid, parathyroid, and adrenal glands).

Tell your doctor if you have ever had:

In animal studies, Bydureon caused thyroid tumors. However, very high doses are used in animal studies. It is not known whether these effects would occur in people using doses recommended for human use. Ask your doctor about your personal risk.

It is not known whether Bydureon BCise will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Bydureon on the baby.


Bydureon BCise is not approved for use by anyone younger than 18 years old.

How should I use Bydureon?



Read and carefully follow any Instructions for Use provided with your medicine. Do not use Bydureon if you don't understand all instructions for proper use. Ask your doctor or pharmacist if you have questions.

Prepare your injection only when you are ready to give it. You must give the injection right away after mixing.

Bydureon is usually injected once every 7 days. Bydureon can be used with or without food and given at any time of the day. Follow your doctor's instructions. You may change your weekly dosing day, but do not inject on your new dosing day if it has been less than 3 days since your last dose.

Your care provider will show you the best places on your body to inject Bydureon. Use a different place each time you give an injection. Do not inject into the same place two times in a row.







Store Bydureon in its original container. Refrigerate and use until expiration date. Protect from light.

Do not freeze Bydureon, and throw away the medicine if it has been frozen.

You may also store Bydureon at room temperature for up to 4 weeks.

What happens if I miss a dose?

Use the missed dose as soon as you remember. Skip the missed dose if your next dose is less than 3 days away. Do not use two doses at one time.

What happens if I overdose?



What should I avoid while taking Bydureon?

You should not use Bydureon together with insulin. Do not use Bydureon together with Byetta.

Avoid drinking alcohol. It can lower your blood sugar.

Bydureon side effects


Stop using Bydureon BCise and call your doctor at once if you have:

  • pain, itching, warmth, swelling, skin sores, blisters, skin changes, or a hard lump where the injection was given;

  • swelling in your neck or throat (enlarged thyroid), hoarse voice, trouble swallowing or breathing;




Common side effects may include:


What other drugs will affect Bydureon?

Bydureon BCise can make it harder for your body to absorb other medicines you take by mouth. Tell your doctor about all your other medicines. Other drugs may affect Bydureon, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

