Mouse Anti-Human ULBP-3

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Size100 µg
Price250 €
CategoryMonoclonal Antibody
Clone Nr.(#6E12)
Species ReactivityHuman
PreparationThis antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse) immunized with Human ULBP-3 recombinant protein.
Antigenrecombinant human ULBP-3
SynonymsULBP1; RAET1I
DescriptionULBP-1, -2, and -3 were originally identified as ligands for the human cytomegalovirus glycoprotein UL16 and designated UL16-binding proteins (ULBP). These proteins are distantly related to major histocompatibility class I (MHC I) molecules, possessing the alpha 1 and alpha 2 Ig-like domains, but lacking the alpha 3 domain. Unlike MHC Class I, they have no capacity to bind peptide or interact with beta2-microglobulin. ULBP-1, -2, and -3 are known to bind to human NKG2D, an activating receptor expressed on NK cells, NKT cells, gamma delta T cells, and CD8+ alpha beta T cells.
Uniprot IDQ9BZM4
Protein RefSeqNP_078794.1
mRNA RefSeqNM_024518.1

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