Scientists develop eye-on-a-chip to improve treatment of diseases

Approximately 14 percent of the world's population suffer from dry eye disease (DED) but treatments are limited because it's difficult to model the complex human eye for drug development. Now though, University of Pennsylvania bioengineers developed an "eye-on-a-chip" complete with a motorized blinking eyelid. The hope is that the artificial eye will lead to a deeper understanding of dry eye disease, enable drug screening, and even become a testbed for contact lens technology and eye surgery. Their technology also received the 2018 Lush Prize awarded for innovations that could help eliminate animal testing for shampoos and other beauty product. From Eurekalert:

In this study, (Dan) Huh and (Jeongyun) Seo focused on engineering an eye model that could imitate a healthy eye and an eye with DED, allowing them to test an experimental drug without risk of human harm.


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Old British rabies paranoia films

Britain is free of rabies; the specter of it being imported from Europe was an omnipresent whisper of menace in public information ad spots and print ads when I was a lad. Here's are three chipper segments from the early 1980s that I recall.

Here's another!

And another!

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Ebola outbreak in Congo: things are getting worse

The latest Ebola outbreak in the Democratic Republic of Congo has proven a sumbitch to contain. Since this latest "oh shit" moment in the history of this infectious outbreak started on August 1st, the brave healthcare professionals and epidemiologists throwing their shoulders into the problem have reported 200 total cases of the disease, 117 confirmed Ebola-related deaths and 35 deaths that are probably related to the illness. This latest outbreak, the 10th to have cropped up in Congo since 1976, is proving more difficult, logistically, than past outbreaks have been. The epicenter of the outbreak is in North Kivu Province: chockablock with danger as government forces, local militias and regional warlords get their violence on. This makes getting folks in the region to the care that they need and, just as vital, containing the disease, far more difficult than it already is.

From The New York Times:

Congolese rebels have killed 15 civilians and abducted a dozen children in an attack in the center of the latest outbreak of the deadly Ebola virus, Congo’s military said Sunday. The violence threatened to again force the suspension of efforts to contain the virus.

Congo’s health ministry has reported “numerous aggressions” in the new outbreak against health workers, who have described hearing gunshots daily. Many are operating under the armed escort of United Nations peacekeepers or Congolese security forces, and ending work by sundown to lower the risk of attack.

The World Health Organization hasn't classified the outbreak as a world health emergency, yet. Read the rest

The Center for Disease Control's realistic new comic about swine flu and a state fair

The US Centers for Disease Control and Prevention have published a free graphic novel titled "The Junior Disease Detectives: Operation Outbreak," some of which is set at a state fair where a teenage 4-H member is infected with swine flu. As CNN reports, the comic's plot is similar to what actually happened this summer at two state fairs. From CNN:



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Artist didn't realize his painting was inspired by a parasitic worm in his eye

Ben Taylor, a 47-year-old artist, was inspired to paint a trippy, colorful circle filled with abstract worm-like patterns. He never finished the work. Years later, Taylor identified the subconscious inspiration for the painting: a 1" African parasitic worm called a Loa loa that he didn't know had taken up residence in his eye but had caused years of illness. Now his painting is on the cover of the medical journal Emerging Infectious Diseases (PDF). From the Washington Post:

“I suppose there was almost a sense of relief . . . just because I realized I wasn’t going mad,” Taylor said of his diagnosis...

While recovering, Taylor began painting again, and while rummaging in his home studio, he came across... the unfinished work he had shelved earlier...

He grabbed his paints and brush and began to finish it. He drew the lashes and the sclera, or the white part of the eye. He painted over the middle, so that the intricate wormlike patterns look like spiraling galaxies disappearing into the dark pupil. He added the worms — long, white and nearly transparent images slithering from the eyelids. “Untitled” became “The Host.”

"His health had been failing for years. Then he saw something crawling in his eye" (Washington Post) Read the rest

Latest Ebola outbreak has come to an end


That wasn’t the case this time.


From the New York Times:



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Ebola keeps on keeping on

Hey gang, let's talk Ebola: Everyone's favorite viral boogeyman.

Over the weekend, the AFP News Agency reported that health professionals in the Democratic Republic of Congo have uncovered five new confirmed cases of Ebola: three cases in the Bikoro area and two in Wangata. This most recent outbreak of the disease in the country’s northwest has resulted in more than 50 confirmed cases and 25 deaths. These numbers, of course, only reflect the incidents of the disease that health agencies such as the World Health Organization and Medecins Sans Frontieres and DR Congo’s healthcare system are aware of.

As such, the push to track everyone who has come into contact with the disease and take appropriate precautions continues, albeit slowly. One of the biggest hurtles in tracking and containing Ebola is that, logistically, the rural regions of DR Congo are a pain in the ass. The roads are often so pocketed with potholes that the only way to reliable traverse them is with a motorcycle—and that’s if there are any roads at all. Many of the smaller villages surrounding Bikoro are packed away by dense jungle. Additionally, cellular coverage in the country’s northwestern region comes with massive holes. This makes doing important work, such as sending field operatives into areas of infection, shipping vaccines or sending collected data back for processing extremely difficult.

According to the New York Times, because of these difficulties, researchers are having a hard time piecing together how the current strain of the virus was transmitted. This, in turn, makes vaccinating the right people in the hopes of stopping the spread of the disease an uphill battle. Read the rest

Map depicts per-city STD rates nationwide



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A beautiful bacterium





Evolution, pregnancy, and food


How animals pass disease to humans


A video featuring "Vomiting Larry"

Meet the robot that pukes for science.

The world's most disgusting Russian nesting dolls


Fear and Trembling: Prion diseases on Twitter


Ebola in Uganda




Unknown respiratory disease in Cambodia
