TY - JOUR T1 - Organization of an echinoderm <em>Hox</em> gene cluster JF - Proceedings of the National Academy of Sciences JO - Proc Natl Acad Sci USA SP - 1469 LP - 1474 DO - 10.1073/pnas.96.4.1469 VL - 96 IS - 4 AU - Martinez, Pedro AU - Rast, Jonathan P. AU - Arenas-Mena, César AU - Davidson, Eric H. Y1 - 1999/02/16 UR - http://www.pnas.org/content/96/4/1469.abstract N2 - The Strongylocentrotus purpuratus genome contains a single ten-gene Hox complex &gt;0.5 megabase in length. This complex was isolated on overlapping bacterial artificial chromosome and P1 artificial chromosome genomic recombinants by using probes for individual genes and by genomic walking. Echinoderm Hox genes of Paralog Groups (PG) 1 and 2 are reported. The cluster includes genes representing all paralog groups of vertebrate Hox clusters, except that there is a single gene of the PG4–5 types and only three genes of the PG9–12 types. The echinoderm Hox gene cluster is essentially similar to those of the bilaterally organized chordates, despite the radically altered pentameral body plans of these animals.PG,Paralog Group;PAC,P1 artificial chromosome;BAC,bacterial artificial chromosome ER -