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PMSF stands for Phenylmethylsulfonyl fluoride. It is used as an irreversible inhibitor of serine protease activity for example in protein purification or co-immunoprecipitation. It has no effect on other proteases that might be present. It can also inactivate some non-proteolytic enzymes that contain serine in the active site.

Molecular W.: 174.19


You can buy PMSF for example at Pierce or Sigma.




PMSF is extremely poisonous and should be handled carefully.

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