Wilson's Temperature Syndrome protocol Even though most of my CFS symptoms are nearly completely gone, my ability to get easily chilled - and then feel badly for a week or two - has remained. In an attempt to remedy this I decided to try Wilson's Temperature Syndrome protocol. My body temperature is consistently 1 - 1.5 degrees lower than normal, and the Wilson protocol of using an extended release T3 (lasting 12 hours) seemed worth trying. Worth noting - my thyroid blood levels have always been within normal range on all tests I've had done. Ordering the assorted bottles of T3 from the Medaus compounding pharmacy is relatively easy if you have a sympathetic physician who is willing to call it in. Following the protocol is also quite doable, though it does require planning and a willingness to check your pulse and blood temperature several times a day. You start off on the lowest dose, 7.5mcg twice a day, and if your pulse doesn't go over 100 beats a minute and you don't have other negative side effects, each day you increase the amount you take. So, its 7.5 mcg 2 x day the first day, 15 mcg 2 x day the second day, 22.5 mcg 2 x day the third day etc.. I finished two courses of the protocol (which takes time as you have to wean yourself down as slowly as you moved up), but unfortunately I was never able to get my average temperature - based on 3 measurements a day - to move up at all. No real side effects except for the occasional quick pulse on the days of max dosage - 75 mcg 2 x day. The web site does mention that it sometimes takes multiple attempts to "jump start" your own thyroid into producing more, so I may give it another try. Not much to lose. Oh, not a very expensive treatment - about $45 for each course.