Celebrex was like taking nothing at all for me. I'm not sure why. I have disk pain from accidents (annular tear, bulge and herniation on various disks), and have also been diagnosed with post-traumatic fibromyalgia. I've also got a bunch of osteoarthritic changes like we all get, so I was given Celebrex to try. It was as if I was taking nothing at all. I felt literally nothing change from taking it. So, onward to try other things. I'm now on a program of duragesic patches with morphine and lidocaine for breakthrough pain. I get around in an electric wheelchair. It's not perfect, but it makes things reasonably bearable.