Mondor's disease

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Mondor's disease
Classification and external resources
ICD-10 I80.8 (ILDS I80.81)
ICD-9 451.89
DiseasesDB 32183
eMedicine derm/909

Mondor's disease (also known as "Mondor's syndrome of superficial thrombophlebitis"[1]) is a rare condition which involves thrombophlebitis of the superficial veins of the breast and anterior chest wall. It sometimes occurs in the arm or penis.[2] In axilla, this condition is known as axillary web syndrome.[3]

Patients with this disease often have abrupt onset of superficial pain, with possible swelling and redness of a limited area of their anterior chest wall or breast. There is usually a lump present, which may be somewhat linear and tender. Because of the possibility of the lump being from another cause, patients are often referred for mammogram and/or breast ultrasound.[4]

Mondor's disease is self-limiting and generally benign. A cause is often not identified, but when found include trauma, surgery, or inflammation such as infection. There have been occasional cases of associated malignancy.[5] Management is with warm compresses and pain relievers, most commonly NSAIDS such as ibuprofen. When thrombophlebitis affects the greater veins, it can progress into deep venous system, and may lead to pulmonary embolism.[6]

It is named after Henri Mondor (1885-1962), a surgeon in Paris, France who first described the disease in 1939.[7]

See also[edit]


  2. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 827. ISBN 0-7216-2921-0. 
  3. ^ Shoham Y, Rosenberg N, Krieger Y, Silberstein E, Arnon O, Bogdanov-Berezovsky A (December 2011). "[Axillary web syndrome--a variant of Mondor's disease, following excision of an accessory breast]". Harefuah (in Hebrew) 150 (12): 893–4, 937, 936. 
  4. ^ Shetty MK, Watson AB (October 2001). "Mondor's disease of the breast: sonographic and mammographic findings". American Journal of Roentgenology 177 (4): 893–6. doi:10.2214/ajr.177.4.1770893. PMID 11566698. 
  5. ^ Catania S, Zurrida S, Veronesi P, Galimberti V, Bono A, Pluchinotta A (May 1992). "Mondor's disease and breast cancer". Cancer 69 (9): 2267–70. doi:10.1002/1097-0142(19920501)69:9<2267::aid-cncr2820690910>;2-u. PMID 1562972. 
  6. ^ Menesez, Nelson. "Superficial thrombophebitis". MedScape. Retrieved 28 August 2012. 
  7. ^ Henri Mondor: Tronculite sous-cutanée subaiqure de la paroi thoracique antero-laterale, In: Mem. Acad. Chir. 1271, 1939

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