Figure 4.

Relation between organ-specific expression of genes and organ-specific hypomethylation of their regulatory regions. For every organ-specific co-module we calculated the overlap between human genes belonging to the co-module and genes reported to be hypomethylated specifically in blood, brain, liver, tongue, skeletal muscle, and testis [10]. Only co-modules with significant overlap are presented on the heat map. The shade of grey corresponds to the corrected P-values of hypergeometric test in log10 scale.

Download authors' original image