Transcriptional Control of Tissue Phagocytes

The Immgen Consortia is a NIH funded consortia whose goal is to establish the immune profile of all hematopoietic cells in mice, in the steady state and upon microbial challenge. Our laboratory focuses on dissecting the transcriptional network that controls the differentiation and function of tissue dendritic cells and, through the consortia, has the privilege to use the broad institute’s facility to perform both microarray and RAseq on tissue phagocytes. This project will provide a unique opportunity to analyze the specific transcriptome of tissue phagocyte in the steady state and inflamed state, across the entire hematopoietic compendium.