1. Mike Birbiglia
NPR commentator, comedian, off-Broadway star, and movie actor—Birbiglia's secret/public journal of his life has been entertaining followers for years.

2. Michael Ian Black
Alum of series like Ed, Stella, The State, and even Celebrity Poker Showdown, Black's a writer/comedian who may be more perfectly suited to 140 characters than any man alive.

3. Ellen DeGeneres
DeGeneres' Twitter bio reads Talk show host, comedian, and "ice road trucker." We know her as the wife of Portia De Rossi and America's sweetheart.

4. Rob Delaney
Twitter made comedian Rob Delaney famous, Rob Delaney made Twitter funny. He's actually been voted Funniest Person on Twitter.

5. Craig Ferguson
Even if you can't stay up "late late" to watch his show, Craig Ferguson is well worth your waking hours on Twitter.

6. Brian Heater
Some might know Brian Heater as a blogger for Engadget or Boing Boing, but we're here to celebrate his tweets. Non sequiturs, travelogues, social commentary... he takes none of them seriously and we're thankful for that.

7. John Hodgman
The world's resident expert in all things—from food to hobos and the apocalypse(s)—is John Hodgman. Read him and learn.

8. Steve Martin
Twitter has a few living legends as members, and Steve Martin—actor, writer, banjo-ista, and yes, THE JERK—is definitely one of them.

9. Eugene Mirman
Russian-born and American-raised, absurdist Eugene Mirman also hosts the yearly Eugene Mirman Comedy Festival in his home borough of Brooklyn.

10. Conan O'Brien
Conan, what is best in life? The talk-show host knows that one funny tweet a day is just about perfect to keep fans happy.

11. Patton Oswalt
Patton Oswalt is a geek's geek, the class-clown who never stopped being funny—even to the bullies!—and got well-deserved fame along the way.

12. Kelly Oxford
Kelly Oxford's witty blogging and tweeting almost became a TV show. Be glad it didn't, because unlike "S#!t My Dad Says," she's still with us daily, bringing the funny.

13. Carl Reiner
Carl Reiner is a comedy legend and at age 91, might be the oldest comedian actively tweeting. But since he's also still acting and performing, typing on his phone between gigs is just keeping him spry.

14. Sarah Silverman
Not Safe for Work could be the slogan of Sarah Silverman and her tweets. Well, at least the ones that aren't just sweet.

15. Karl Welzein
We'll admit, we have no idea if "Karl Welzein" is a real person, but as the persona behind the DadBoner account, he has created one of Twitter's funniest accounts of a man obsessed with processed foods.