Harvard Health Letters


A. Although allergies don't usually directly increase blood pressure, they can contribute indirectly to high blood pressure in two very different ways.

Decongestants commonly used by people with allergies, such as pseudoephedrine (Sudafed, Actifed, others) and phenylephrine (Sudafed PE), constrict small blood vessels in the nose. Although this eases nasal congestion and improves breathing, the effect isn't limited to the nose. Constricted blood vessels throughout the body mean the heart must work harder to pump blood. This increases blood pressure.

If you take an over-the-counter allergy product, look for one that doesn't contain pseudoephedrine or phenylephrine. Antihistamines such as cetirizine (Zyrtec), chlorpheniramine (Chlor-Trimeton), diphenhydramine (Benadryl), and loratadine (Claritin) can help with the congestion that accompanies allergies and are safer for the heart. Another option is to use a nasal spray, which acts directly on the blood vessels in the nose and has less impact elsewhere in the body.
