10.1021/acs.orglett.6b00722.s001 Sheng-Ying Hsieh Jeffrey W. Bode Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones 2016 American Chemical Society silicon Amine Reagents tin amine protocol aliphatic aldehydes Photocatalytic Synthesis piperazine SLAP reagents form N Ketones Silicon amine protocol 2016-04-21 13:06:22 article https://acs.figshare.com/articles/Silicon_Amine_Reagents_for_the_Photocatalytic_Synthesis_of_Piperazines_from_Aldehydes_and_Ketones/3188005 Silicon amine protocol (SLAP) reagents for photocatalytic cross-coupling with aldehydes and ketones to form <i>N</i>-unprotected piperazines have been developed. This blue light promoted process tolerates a wide range of heteroaromatic, aromatic, and aliphatic aldehydes and structurally and stereochemically complex SLAP reagents. It provides a tin-free alternative to SnAP (tin amine protocol) reagents for the synthesis of substituted piperazines.