PrimePCR™ ddPCR™ Expression EvaGreen® Assay: CRYZ, Human



Info:   EG; Same primer pair as used in qPCR assay qHsaCED0057473; exonic

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Assay Information

Technology:   ddPCR
Assay Type:   EvaGreen
Application:   Gene Expression
Unique Assay ID:   dHsaEG5013986
Chromosome Location:   1:75188820-75188954question
Amplicon Length:   105

Gene Information

Crystallins are separated into two classes: taxon-specific or enzyme and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species in humans lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist. [provided by RefSeq Sep 2008]

Gene Symbol:   CRYZ
Gene Name:   crystallin, zeta (quinone reductase)
Aliases:   DKFZp779E0834, FLJ41475
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000116791
Entrez:   1429
UniGene:   Hs.83114
Chromosome Mapping:   1p31-p22

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