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Abstract #1434

Diffusion Anisotropy Measure Based on the Basis of Tesseral Harmonics

Yuliya Kupriyanova1, Oleg Posnansky1, N. Jon Shah1,2

1Institute of Neurosciences and Biophysics, Research Centre Juelich, Juelich, Germany; 2Faculty of Medicine, Department of Neurology, RWTH Aachen University, JARA, Aachen, Germany

We present a method for the characterization of diffusion anisotropy based on the analysis of the apparent diffusion coefficient profile in terms of the tesseral harmonics series coefficients with a resulting brain anisotropy map. The tesseral harmonics are an alternative set of spherical harmonics for real-valued functions. To infer the underlying diffusion process, we applied the rotationally-invariant anisotropy index. The characterization of the diffusion anisotropy based on our method is computationally simple, fast and is consistent with the known fibre anatomy.