This information is for you if you’re considering or have been prescribed treatment with tofacitinib (Xeljanz) for Ulcerative Colitis. It looks at:

• what you can expect from treatment
• how the medicine works
• possible side effects
• stopping or changing treatment.

Our information can support you to make an informed decision about treatment that’s right for you.

Other names for this medicine
Why am I being offered treatment with tofacitinib?
How effective is tofacitinib?
How does it work?
How long does it take to work?
How do I take tofacitinib?
How long will I be taking it?
What's the normal dose?
Can tofacitinib be used in combination with other drugs to treat Ulcerative Colitis?
Is it safe to take other medicines with tofacitinib?
Do I need any checks before I start treatment?
Do I need ongoing checks?
Will I need to take any special precautions?
What are the most likely side effects of tofacitinib?
Can I have immunisations while on tofacitinib?
Does tofacitinib affect fertility or pregnancy?
Can I drink alcohol
Stopping or changing treatment
Who should I talk to if I'm worried?
Help and support from Crohn's & Colitis UK

Last reviewed: October 2019