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    1. Neuroscience

    Maturation of metabolic connectivity of the adolescent rat brain

    Hongyoon Choi et al.
    Rat brains mature to increase metabolic connectivity between network components and establish energy efficiency in the midline structures from childhood to early adulthood.
    1. Immunology and Inflammation

    Long-term antigen exposure irreversibly modifies metabolic requirements for T cell function

    Marie Bettonville et al.
    Long-term exposure to recipient's alloantigens promotes major metabolic defects in T cells that are independent of PD-1-mediated regulation.
    1. Cancer Biology


    Shun Kishimoto et al.
    1. Ecology
    2. Evolutionary Biology

    Reduced metabolism supports hypoxic flight in the high-flying bar-headed goose (Anser indicus)

    Jessica U Meir et al.
    Measurements of bar-headed geese flying in a wind tunnel in hypoxia reveal that these birds sustain aerobic flight at high altitude via a reduction in metabolism.
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    Switching of metabolic programs in response to light availability is an essential function of the cyanobacterial circadian output pathway

    Anna M Puszynska, Erin K O'Shea
    The circadian clock of Synechococcus elongatus PCC7942 schedules the activity of the transcription factor RpaA, which controls key events in carbon metabolism that contribute to cell fitness in conditions mimicking the natural environment.
    1. Evolutionary Biology

    Ongoing resolution of duplicate gene functions shapes the diversification of a metabolic network

    Meihua Christina Kuang et al.
    Recent functional changes in ancient duplicate genes led to the evolution of divergent regulatory and metabolic strategies by the GALactose gene networks of two yeast species.
    1. Cell Biology
    2. Neuroscience


    Piergiorgio La Rosa et al.
    1. Cell Biology
    2. Immunology and Inflammation


    Anthony J Covarrubias et al.
    Interleukin 4 signaling co-opts the Akt-mTORC1-Acly pathway to couple metabolic input to the control of energetically demanding processes during macrophage M2 activation.
    1. Cell Biology
    2. Human Biology and Medicine

    Tumor microenvironment derived exosomes pleiotropically modulate cancer cell metabolism

    Hongyun Zhao et al.
    1. Human Biology and Medicine
    2. Neuroscience

    Insulin regulates POMC neuronal plasticity to control glucose metabolism

    Garron T Dodd et al.
    Feeding and fasting associated alterations in proopiomelanocortin neuronal responses to insulin coordinate glucose metabolism.