Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07 Gene Set

Dataset TCGA Signatures of Differentially Expressed Genes for Tumors
Category transcriptomics
Type tissue sample
Description tissue sample derived from Kidney renal clear cell carcinoma_KIRC (The Cancer Genome Atlas)
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378 genes with high or low expression in Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07 relative to other tissue samples from the TCGA Signatures of Differentially Expressed Genes for Tumors dataset.

high expression

Symbol Name
AAED1 AhpC/TSA antioxidant enzyme domain containing 1
AAMP angio-associated, migratory cell protein
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADIRF adipogenesis regulatory factor
ADORA2A adenosine A2a receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AHCY adenosylhomocysteinase
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase
ALG5 ALG5, dolichyl-phosphate beta-glucosyltransferase
ALG8 ALG8, alpha-1,3-glucosyltransferase
ANKRD37 ankyrin repeat domain 37
ANKRD39 ankyrin repeat domain 39
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
ARMC10 armadillo repeat containing 10
ASNSD1 asparagine synthetase domain containing 1
ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
ATRAID all-trans retinoic acid-induced differentiation factor
AUP1 ancient ubiquitous protein 1
B2M beta-2-microglobulin
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BHLHE23 basic helix-loop-helix family, member e23
BLVRA biliverdin reductase A
BRIX1 BRX1, biogenesis of ribosomes
BTN3A2 butyrophilin, subfamily 3, member A2
BTN3A3 butyrophilin, subfamily 3, member A3
C10ORF107 chromosome 10 open reading frame 107
C16ORF54 chromosome 16 open reading frame 54
C1QL4 complement component 1, q subcomponent-like 4
C21ORF59 chromosome 21 open reading frame 59
C2ORF47 chromosome 2 open reading frame 47
C2ORF73 chromosome 2 open reading frame 73
C6ORF165 chromosome 6 open reading frame 165
C9ORF116 chromosome 9 open reading frame 116
CALCR calcitonin receptor
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC109B coiled-coil domain containing 109B
CCDC110 coiled-coil domain containing 110
CCDC127 coiled-coil domain containing 127
CCDC74B coiled-coil domain containing 74B
CCNB3 cyclin B3
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CD2 CD2 molecule
CD200R1 CD200 receptor 1
CD200R1L CD200 receptor 1-like
CD247 CD247 molecule
CD27 CD27 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD48 CD48 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD8B CD8b molecule
CDC42SE2 CDC42 small effector 2
CDH22 cadherin 22, type 2
CDHR2 cadherin-related family member 2
CERKL ceramide kinase-like
CETN3 centrin, EF-hand protein, 3
CFAP36 cilia and flagella associated protein 36
CKLF chemokine-like factor
CLEC9A C-type lectin domain family 9, member A
CLECL1 C-type lectin-like 1
CLIC1 chloride intracellular channel 1
CLRN1-AS1 CLRN1 antisense RNA 1
CNBD2 cyclic nucleotide binding domain containing 2
CNNM3 cyclin and CBS domain divalent metal cation transport mediator 3
CNOT11 CCR4-NOT transcription complex, subunit 11
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COMMD1 copper metabolism (Murr1) domain containing 1
COPS8 COP9 signalosome subunit 8
CORO2A coronin, actin binding protein, 2A
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa
CREB3 cAMP responsive element binding protein 3
CSE1L CSE1 chromosome segregation 1-like (yeast)
CST7 cystatin F (leukocystatin)
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
CTSO cathepsin O
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR6 chemokine (C-X-C motif) receptor 6
CXXC5 CXXC finger protein 5
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DDRGK1 DDRGK domain containing 1
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DNM2 dynamin 2
DNPEP aspartyl aminopeptidase
DOLK dolichol kinase
DUSP11 dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
DYNLRB2 dynein, light chain, roadblock-type 2
EFCAB7 EF-hand calcium binding domain 7
EFHC2 EF-hand domain (C-terminal) containing 2
ELOVL1 ELOVL fatty acid elongase 1
ENDOG endonuclease G
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2
ERP44 endoplasmic reticulum protein 44
EVA1C eva-1 homolog C (C. elegans)
EXOSC2 exosome component 2
EXOSC3 exosome component 3
FABP7 fatty acid binding protein 7, brain
FAM120AOS family with sequence similarity 120A opposite strand
FAM138D family with sequence similarity 138, member D
FAM188B family with sequence similarity 188, member B
FAM206A family with sequence similarity 206, member A
FAM213B family with sequence similarity 213, member B
FANCC Fanconi anemia, complementation group C
FAR2 fatty acyl CoA reductase 2
FARSB phenylalanyl-tRNA synthetase, beta subunit
FASLG Fas ligand (TNF superfamily, member 6)
FASTKD2 FAST kinase domains 2
FBXO16 F-box protein 16
FBXO27 F-box protein 27
FGG fibrinogen gamma chain
FMO2 flavin containing monooxygenase 2 (non-functional)
FXYD1 FXYD domain containing ion transport regulator 1
FZD3 frizzled class receptor 3
GABRA5 gamma-aminobutyric acid (GABA) A receptor, alpha 5
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GBP2 guanylate binding protein 2, interferon-inducible
GBP4 guanylate binding protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GLE1 GLE1 RNA export mediator
GLUD1 glutamate dehydrogenase 1
GLYATL2 glycine-N-acyltransferase-like 2
GPN1 GPN-loop GTPase 1
GPR108 G protein-coupled receptor 108
GPR18 G protein-coupled receptor 18
GPR25 G protein-coupled receptor 25
GPR85 G protein-coupled receptor 85
GPR89B G protein-coupled receptor 89B
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GTF2B general transcription factor IIB
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMK granzyme K (granzyme 3; tryptase II)
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HAT1 histone acetyltransferase 1
HAUS1 HAUS augmin-like complex, subunit 1
HAVCR2 hepatitis A virus cellular receptor 2
HINT1 histidine triad nucleotide binding protein 1
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DOB major histocompatibility complex, class II, DO beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HLA-E major histocompatibility complex, class I, E
HLA-F major histocompatibility complex, class I, F
HLA-G major histocompatibility complex, class I, G
HLA-H major histocompatibility complex, class I, H (pseudogene)
HMGN4 high mobility group nucleosomal binding domain 4
HNMT histamine N-methyltransferase
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPE1 heat shock 10kDa protein 1
HTRA2 HtrA serine peptidase 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER5L immediate early response 5-like
IFI35 interferon-induced protein 35
IFIH1 interferon induced with helicase C domain 1
IHH indian hedgehog
IL10RB interleukin 10 receptor, beta
IL17F interleukin 17F
IRF1 interferon regulatory factor 1
KCNK3 potassium channel, two pore domain subfamily K, member 3
KIAA0895 KIAA0895
KRTAP19-3 keratin associated protein 19-3
KTI12 KTI12 homolog, chromatin associated (S. cerevisiae)
KYNU kynureninase
LDAH lipid droplet associated hydrolase
LEPROTL1 leptin receptor overlapping transcript-like 1
LGI4 leucine-rich repeat LGI family, member 4
LINC00094 long intergenic non-protein coding RNA 94
LINC00515 long intergenic non-protein coding RNA 515
LINC01600 long intergenic non-protein coding RNA 1600
LIPT1 lipoyltransferase 1
LMAN2L lectin, mannose-binding 2-like
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MALL mal, T-cell differentiation protein-like
MAN1B1 mannosidase, alpha, class 1B, member 1
MCM6 minichromosome maintenance complex component 6
METTL21A methyltransferase like 21A
METTL5 methyltransferase like 5
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
MITD1 MIT, microtubule interacting and transport, domain containing 1
MMADHC methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
MOB4 MOB family member 4, phocein
MORN5 MORN repeat containing 5
MRPL39 mitochondrial ribosomal protein L39
MRPL44 mitochondrial ribosomal protein L44
MRPS18A mitochondrial ribosomal protein S18A
MRPS9 mitochondrial ribosomal protein S9
N6AMT1 N-6 adenine-specific DNA methyltransferase 1 (putative)
NAAA N-acylethanolamine acid amidase
NANS N-acetylneuraminic acid synthase
NDRG3 NDRG family member 3
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2
NELL2 NEL-like 2 (chicken)
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NFU1 NFU1 iron-sulfur cluster scaffold
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae)
NIPSNAP3A nipsnap homolog 3A (C. elegans)
NKG7 natural killer cell granule protein 7
NMI N-myc (and STAT) interactor
NOL6 nucleolar protein 6 (RNA-associated)
NOSTRIN nitric oxide synthase trafficking
NPHP1 nephronophthisis 1 (juvenile)
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae)
NTS neurotensin
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NXT1 nuclear transport factor 2-like export factor 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OLA1 Obg-like ATPase 1
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PADI6 peptidyl arginine deiminase, type VI
PAOX polyamine oxidase (exo-N4-amino)
PCDHB13 protocadherin beta 13
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD6 programmed cell death 6
PDCL3 phosducin-like 3
PDLIM4 PDZ and LIM domain 4
PECR peroxisomal trans-2-enoyl-CoA reductase
PGBD5 piggyBac transposable element derived 5
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIGP phosphatidylinositol glycan anchor biosynthesis, class P
PNO1 partner of NOB1 homolog (S. cerevisiae)
PPIAL4C peptidylprolyl isomerase A (cyclophilin A)-like 4C
PPIAL4G peptidylprolyl isomerase A (cyclophilin A)-like 4G
PPIL3 peptidylprolyl isomerase (cyclophilin)-like 3
PPP1R7 protein phosphatase 1, regulatory subunit 7
PQLC3 PQ loop repeat containing 3
PREB prolactin regulatory element binding
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8
PSMB10 proteasome (prosome, macropain) subunit, beta type, 10
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PSMG1 proteasome (prosome, macropain) assembly chaperone 1
PTPRCAP protein tyrosine phosphatase, receptor type, C-associated protein
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
PTTG1IP pituitary tumor-transforming 1 interacting protein
RAB10 RAB10, member RAS oncogene family
RABEPK Rab9 effector protein with kelch motifs
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFPL4A ret finger protein-like 4A
RGPD1 RANBP2-like and GRIP domain containing 1
RLN2 relaxin 2
RNF114 ring finger protein 114
RPA3 replication protein A3, 14kDa
RRAGA Ras-related GTP binding A
RSPH1 radial spoke head 1 homolog (Chlamydomonas)
RSPH9 radial spoke head 9 homolog (Chlamydomonas)
RTP4 receptor (chemosensory) transporter protein 4
S1PR4 sphingosine-1-phosphate receptor 4
SBK2 SH3 domain binding kinase family, member 2
SCARNA11 small Cajal body-specific RNA 11
SCARNA8 small Cajal body-specific RNA 8
SCN1B sodium channel, voltage gated, type I beta subunit
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
SEC61B Sec61 beta subunit
SECTM1 secreted and transmembrane 1
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEPT7P9 septin 7 pseudogene 9
SET SET nuclear proto-oncogene
SF3B6 splicing factor 3b, subunit 6, 14kDa
SFT2D3 SFT2 domain containing 3
SGCE sarcoglycan, epsilon
SH2D1A SH2 domain containing 1A
SIGMAR1 sigma non-opioid intracellular receptor 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC35A1 solute carrier family 35 (CMP-sialic acid transporter), member A1
SLC35D2 solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2
SLC51A solute carrier family 51, alpha subunit
SLC6A19 solute carrier family 6 (neutral amino acid transporter), member 19
SLC9B2 solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2
SMAD5-AS1 SMAD5 antisense RNA 1
SMYD5 SMYD family member 5
SNORA16A small nucleolar RNA, H/ACA box 16A
SNORA49 small nucleolar RNA, H/ACA box 49
SNORA64 small nucleolar RNA, H/ACA box 64
SNORA76A small nucleolar RNA, H/ACA box 76A
SNX17 sorting nexin 17
SPATA4 spermatogenesis associated 4
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
SRBD1 S1 RNA binding domain 1
SSBP1 single-stranded DNA binding protein 1, mitochondrial
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STAP2 signal transducing adaptor family member 2
STARD3NL STARD3 N-terminal like
STK16 serine/threonine kinase 16
STMN3 stathmin-like 3
STOML2 stomatin (EPB72)-like 2
STOML3 stomatin (EPB72)-like 3
SUB1 SUB1 homolog (S. cerevisiae)
SUGT1P1 SUGT1 pseudogene 1
SUMO1 small ubiquitin-like modifier 1
SURF4 surfeit 4
SYS1 Sys1 golgi trafficking protein
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TDP2 tyrosyl-DNA phosphodiesterase 2
TDRD7 tudor domain containing 7
TGM2 transglutaminase 2
THADA thyroid adenoma associated
TIGIT T cell immunoreceptor with Ig and ITIM domains
TINAG tubulointerstitial nephritis antigen
TM2D2 TM2 domain containing 2
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM176A transmembrane protein 176A
TMEM179 transmembrane protein 179
TMEM198 transmembrane protein 198
TMEM203 transmembrane protein 203
TMEM50A transmembrane protein 50A
TMEM60 transmembrane protein 60
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TOMM5 translocase of outer mitochondrial membrane 5 homolog (yeast)
TOR1A torsin family 1, member A (torsin A)
TOR1B torsin family 1, member B (torsin B)
TOR4A torsin family 4, member A
TP53RK TP53 regulating kinase
TPRKB TP53RK binding protein
TPST1 tyrosylprotein sulfotransferase 1
TRAPPC4 trafficking protein particle complex 4
TRHR thyrotropin-releasing hormone receptor
TRIM14 tripartite motif containing 14
TRMT61B tRNA methyltransferase 61B
TSPAN4 tetraspanin 4
TTC27 tetratricopeptide repeat domain 27
TUBA4A tubulin, alpha 4a
TXN thioredoxin
TXNDC9 thioredoxin domain containing 9
UBD ubiquitin D
UBE2F ubiquitin-conjugating enzyme E2F (putative)
UBE2L6 ubiquitin-conjugating enzyme E2L 6
VAMP8 vesicle-associated membrane protein 8
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
WDR38 WD repeat domain 38
XCL1 chemokine (C motif) ligand 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
YBEY ybeY metallopeptidase (putative)
ZBED9 zinc finger, BED-type containing 9
ZCCHC3 zinc finger, CCHC domain containing 3
ZNF324 zinc finger protein 324

low expression

Symbol Name
ANKRD11 ankyrin repeat domain 11
ATG14 autophagy related 14
CASC3 cancer susceptibility candidate 3
DCAF5 DDB1 and CUL4 associated factor 5
FBXW8 F-box and WD repeat domain containing 8
KANSL1 KAT8 regulatory NSL complex subunit 1
NFRKB nuclear factor related to kappaB binding protein
R3HDM2 R3H domain containing 2
RNF214 ring finger protein 214
SLTM SAFB-like, transcription modulator
SP2 Sp2 transcription factor
SRCAP Snf2-related CREBBP activator protein
TFDP1 transcription factor Dp-1