Effect Of Ventilation Technique And Airway Diameter On Bronchial Lumen To Pulmonary Artery Diameter Ratios In Clinically Normal Beagle Dogs

Makara M, Dennler M, Schnyder M, et al.

Vet Radiol Ultrasound 2013.

In dogs, a mean broncho-arterial ratio of 1.45 +/- 0.21 has been previously defined as normal. These values were obtained in dogs under general inhalational anesthesia using a single breath-hold technique. The purpose of the study was to determine whether ventilation technique and bronchial diameter have an effect on broncho-arterial ratios. Four healthy Beagle dogs were scanned twice, each time with positive-pressure inspiration and end expiration. For each ventilation technique, broncho-arterial ratios were grouped into those obtained from small or large bronchi using the median diameter of the bronchi as the cutoff value. Mean broncho-arterial ratios obtained using positive-pressure inspiration (1.24 +/- 0.23) were statistically greater than those obtained at end expiration (1.11 +/- 0.20) P = 0.005. There was a strong positive correlation between bronchial diameter and broncho-arterial ratios for both ventilation techniques (positive-pressure inspiration rs = .786, P < 0.0005 and end expiration rs = .709, P < 0.0005). Mean broncho-arterial ratio for the large bronchi obtained applying positive-pressure inspiration was 1.39 cm +/- 0.20 and during end expiration was 1.22 cm +/- 0.20. Mean broncho-arterial ratio for the small bronchi obtained during positive-pressure inspiration was 1.08 cm +/- 0.13 and during end expiration was 1.01 cm +/- 0.13. There was a statistically significant difference between these groups (F = 248.60, P = 0.005). Findings indicated that reference values obtained using positive-pressure inspiration or from the larger bronchi may not be applicable to dogs scanned during end expiration or to the smaller bronchi.