Glutamate and Nitric Oxide: potentially promising biomarkers in multiple sclerosis.


  • Nitric Oxide (NO) and glutamate may be potential biomarkers for disease activity in patients with multiple sclerosis (MS).

Why this matters

  • Although there are several diagnostic tests, MS remains a clinical diagnosis based on supportive paraclinical evidence.

  • However, glutamate and NO may be promising as biomarkers for predicting the occurrence or relapse in a MS patient and be objective clues for the diagnosis of a relapse, especially when pseudo-relapse is suspected.