document: The increase in the median survival time (ISTmedian; in %) of the X-ray irradiation group was set as the standard baseline (ISTmedian = 100%); the ISTmedian for the mice that received the combination of rQβ@b-3WJsiEGFR Let-7g pre-treatment with 2Gy of X-ray irradiation increased to 132%, indicating that the rQβ@b-3WJsiEGFR Let-7g can inhibit DNA repair process to enhance the efficiency of radiotherapy. However, it is worth noting that the ISTmedian increased nearly 1.5-fold to 194% when the mice