document: any treatment (control; 160.5 ± 44.0 mm3 on Day 34 and 179.7 ± 22.8 mm3 on Day 41) and the mice that received two doses of TrQβ VLPs via CED infusion (141.3 ± 53.2 mm3 on Day 34 and 171.3 ± 40.1 mm3 on Day 41) all developed large brain tumours in the treated hemisphere, resulting in a median survival time of 27 days and 32 days for the control and TrQβ VLPs-treated groups, respectively. Although the tumour-bearing mice that received two rounds of 2Gy X-ray irradiation or two doses of