document: (MALDI-TOF MS) and sodium dodecyl sulfate (SDS)-PAGE. The representative MALDI-TOF MS spectra of Qβ@b-3WJsiEGFR siLUC and TQβ@b-3WJsiEGFR siLUC are shown in Figure 3d and 3e. For TQβ@b-3WJsiEGFR siLUC, new peaks appeared at m/z 5,390, m/z 8,095, and m/z 16,505 VLPs belong to one 3H+ ionized TAT-conjugated Qβ capsid protein (TQβCP), 2H+ ionized TQβCP, and H+ ionized TQβCP compared with Qβ@b-3WJsiEGFR siLUC, indicating that TAT peptides were indeed conjugated on the surface of Qβ@b-3WJsiEGFR