document: costs and lower yields. The presented technique in this study has shown that the biological production of 3WJ RNAs followed by immediate self-assembly in bacteriophage particles can greatly protect the RNA molecules from degradation by Rnase. For intracellular RNA distribution monitoring, RNA molecules are usually modified with fluorophores at either their 5’ or 3’ end for intracellular RNA distribution monitoring using fluorescence microscopy, but their further cleavage status with Dicer enzyme