document: (13.31% for rQβ@b-3WJsiEGFR Let-7g) compared with control group. These results indicating that TrQβ@b-3WJsiEGFR Let-7g can deliver more b-3WJsiEGFR Let-7g than rQβ@b-3WJsiEGFR Let-7g into U87MG cells to significantly enhance the efficiency of radiotherapy by effectively downregulating the expression of NF-κB because the overexpression of NF-κB promotes DNA repair.40 In addition, inhibition of EGFR and IKK complex expression by TrQβ@b-3WJsiEGFR Let-7g not only inhibited DNA repair but also