document: Furthermore, the TAT peptide was modified on the surface of rQβ@b-3WJsiEGFR siLUC to enhance cellular internalization, most likely because the TAT peptide originates from the HIV transactivator of transcription protein, which has demonstrated excellent potential in translocating across the plasma membrane of various cell types. Successful TAT peptide conjugation was confirmed by Matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) and sodium dodecyl sulfate