document: (Figure 5e). We then quantified the gene silencing efficiency of rQβ@b-3WJsiEGFR Let-7g and TrQβ@b-3WJsiEGFR Let-7g for EGFR, IKKα, and NF-κB in U87MG cells using flow cytometry (Figure S10). The results showed that the TrQβ@b-3WJsiEGFR Let-7g could inhibit approximately 52.05% of EGFR protein expression (28.18% for rQβ@b-3WJsiEGFR Let-7g), 36.87% of IKKα protein expression (25.60% for rQβ@b-3WJsiEGFR Let-7g), and 36.37% of NF-κB protein expression (13.31% for rQβ@b-3WJsiEGFR Let-7g) compared