document: rate of the control group (without any treatment), WT-Qβ, and rQβ@b-3WJsiEGFR Let-7g treatment groups (Figure S13). According to above results, TrQβ@b-3WJsiEGFR Let-7g (with TAT peptide conjugation) have been proven have superior cell penetration efficiency than rQβ@b-3WJsiEGFR Let-7g (without TAT peptide conjugation). Therefore, we then investigated the in vitro synergistic effect of EGFR/IKKα gene silencing and X-ray irradiation (Figure S14), the cell viability of U87MG cells through the