document: siLUC can be indeed delivered into tumour cells. The green fluorescence in cells gradually disappeared with increasing incubation time, while the intracellular red fluorescence did not decrease at all. The results indicated that b-3WJsiEGFR siLUC can be successfully delivered into cells by TrQβ VLPs and that its cleavage status with the Dicer enzyme can easily be monitored by fluorescence microscopy in real time.