. The first group stayed in the Story room and were exposed to a range of activities to inspire writing, recording any inspiration in their very own ‘Story Idea’ books. The other group explored Boy Gallery and Solo Gallery. The groups then swapped activities.
In Boy Gallery, the children found out about Roald Dahl's childhood, his love of chocolate and his schoolboy pranks. They were able to dress up in Roald Dahl’s old school uniform, read his school reports and read letters that Roald Dahl wrote to his family members.
In Solo Gallery, the children were shown how Roald Dahl's real-life adventures led him to become a writer, working from a small hut in his garden. The children were shown a collection of quirky mementos collected by Roald Dahl; including his silver ball of Kit Kat wrappers, Roald Dahl’s false teeth and part of his femur (yes we are talking about his leg bone!).
Brittany Francis
Communications Director
(225) 219-3306 Office
(225) 266-8834 Cell
Tyana Daquano
Public Information Officer
(225) 342-5173 Office
Louisiana Office of Student Financial Assistance (LOSFA)
January 7, 2019
LOSFA hosts Third annual FAFSA tournament for high school seniors
Baton Rouge
-
Staff from the Louisiana Office of Student Financial Assistance (LOSFA) were at the Bob Petit Coca Cola Basketball Tournament at Lee Magnet High School, for the annual FAFSA Tournament. The program, held December 26-29, 2018, is in its third year. It is designed to help high school seniors complete their federal financial aid application. Seniors and their parents who had not begun the application, had incomplete applications or received submission errors were able to ask questions and make the necessary corrections.
The FAFSA Tournament is one component of LOSFA’S outreach effort to drive students to complete the FAFSA and enter a post-secondary institution upon high school completion.
"When we first started holding the FAFSA tournament three years ago, it was part of a competition between the schools. While their schools were competing on the court, they could also compete and check off some things on their college checklist," said Dr. Tireka Cobb, director of LOSFA's Field Outreach Services. "Now, they can win off the court and help their schools ranking on our
Compete to Complete
website, which tracks how many students have completed a FAFSA at schools around the state."
Christion Little, a senior at Scotlandville Magnet High School, attended the FAFSA Tournament. Little is one of LOSFA’S Trailblazers, another program for high school seniors who demonstrate exemplary leadership skills in order to help their peers better understand college access and financial literacy.
“I wanted to be an advocate for LOSFA and help my peers become more informed on resources that will help us go to college after we graduate high school," Little said, noting that completing the FAFSA is an important step to finding financial aid for college. "What better way to fix a problem than to be a part of the solution.”
More than 50 parents and students were assisted with FAFSA completion.
"We've determined being available with one-on-one help is the best way to make sure students and their families are able to complete their financial aid forms, without errors," Dr. Cobb said.
LOSFA aims to continue to provide these services and aid students in a successful transition from their final years of high school and throughout their first year of college.!< General > Plain logos are printed with silicone in tape The silicone printed tape is woven with the pants as shown in the picture. The silicone has adhesiveness in its nature, So it pervents the shirts from slipping off from the pants. It is widely used in golf wears and pants that are worn in an environment that requires a lot of physical activity.Design for Manufacturability’ (DFM) is a methodology that involves designing with an intent to minimize the cost of production and time-to-market, without compromising on the quality of the product.
How to review a design manually considering all the recommended guidelines.
How to transfer manufacturing-related inputs to the design team.
Ensure mistakes are not repeated, especially by newbie design engineers.
Identify areas in a design that are difficult.
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
- PMID: 11242085
- DOI: 10.1038/35065638
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
Abstract
In Caenorhabditis elegans, mutations that reduce the activity of an insulin-like receptor (daf-2) or a phosphatidylinositol-3-OH kinase (age-1) favour entry into the dauer state during larval development and extend lifespan in adults. Downregulation of this pathway activates a forkhead transcription factor (daf-16), which may regulate targets that promote dauer formation in larvae and stress resistance and longevity in adults. In yeast, the SIR2 gene determines the lifespan of mother cells, and adding an extra copy of SIR2 extends lifespan. Sir2 mediates chromatin silencing through a histone deacetylase activity that depends on NAD (nicotinamide adenine dinucleotide) as a cofactor. We have surveyed the lifespan of C. elegans strains containing duplications of chromosomal regions. Here we report that a duplication containing sir-2.1-the C. elegans gene most homologous to yeast SIR2-confers a lifespan that is extended by up to 50%. Genetic analysis indicates that the sir-2.1 transgene functions upstream of daf-16 in the insulin-like signalling pathway. Our findings suggest that Sir2 proteins may couple longevity to nutrient availability in many eukaryotic organisms.
Comment in
- Ageing. Yeast longevity gene goes public.Nature. 2001 Mar 8;410(6825):154-5. doi: 10.1038/35065765. Nature. 2001. PMID: 11258373 No abstract available.
- Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes.Nature. 2011 Sep 21;477(7365):E1-2. doi: 10.1038/nature10440. Nature. 2011. PMID: 21938026 No abstract available.
- Ageing: a midlife crisis for sirtuins.Nat Rev Mol Cell Biol. 2011 Oct 21;12(11):688. doi: 10.1038/nrm3218. Nat Rev Mol Cell Biol. 2011. PMID: 22016053 No abstract available.
Similar articles
- Nicotinamide adenine dinucleotide extends the lifespan of Caenorhabditis elegans mediated by sir-2.1 and daf-16.Biogerontology. 2010 Feb;11(1):31-43. doi: 10.1007/s10522-009-9225-3. Epub 2009 Apr 16. Biogerontology. 2010. PMID: 19370397
- Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase.Nature. 2000 Feb 17;403(6771):795-800. doi: 10.1038/35001622. Nature. 2000. PMID: 10693811
- Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration.Nature. 2002 Jul 18;418(6895):344-8. doi: 10.1038/nature00829. Nature. 2002. PMID: 12124627
- The Sir2 protein family: A novel deacetylase for gene silencing and more.Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14030-2. doi: 10.1073/pnas.011506198. Proc Natl Acad Sci U S A. 2000. PMID: 11114164 Free PMC article. Review. No abstract available.
- Sound silencing: the Sir2 protein and cellular senescence.Bioessays. 2001 Apr;23(4):327-32. doi: 10.1002/bies.1047. Bioessays. 2001. PMID: 11268038 Review.
Cited by
- Transcriptome Analysis of Beet Webworm Shows That Histone Deacetylase May Affect Diapause by Regulating Juvenile Hormone.Insects. 2022 Sep 14;13(9):835. doi: 10.3390/insects13090835. Insects. 2022. PMID: 36135537 Free PMC article.
- Monoterpenes as Sirtuin-1 Activators: Therapeutic Potential in Aging and Related Diseases.Biomolecules. 2022 Jun 30;12(7):921. doi: 10.3390/biom12070921. Biomolecules. 2022. PMID: 35883477 Free PMC article. Review.
- Oligosaccharides from agar extends lifespan through activation of unfolded protein response via SIR-2.1 in Caenorhabditis elegans.Eur J Nutr. 2022 Jul 21. doi: 10.1007/s00394-022-02957-1. Online ahead of print. Eur J Nutr. 2022. PMID: 35864340
- ADAR1 downregulation by autophagy drives senescence independently of RNA editing by enhancing p16INK4a levels.Nat Cell Biol. 2022 Aug;24(8):1202-1210. doi: 10.1038/s41556-022-00959-z. Epub 2022 Jul 18. Nat Cell