 (New York: M. Kennerley, 1913).
Bliss Carman and Mary Perry King. Earth Deities: And Other Rhythmic Masques. (New York: M. Kennerley, 1914).
This page is based on the Wikipedia article Bliss Carman; it is used under the Creative Commons Attribution-ShareAlike 3.0 Unported License (CC-BY-SA). You may redistribute it, verbatim or modified, providing that you comply with the terms of the CC-BY-SA.Evaluation of quinazoline analogues as glucocerebrosidase inhibitors with chaperone activity.

Gaucher disease is a lysosomal storage disorder (LSD) caused by deficiency in the enzyme glucocerebrosidase (GC). Small molecule chaperones of protein folding and translocation have been proposed as a promising therapeutic approach to this LSD. Most small molecule chaperones described in the literature contain an iminosugar scaffold. Here we present the discovery and evaluation of a new series of GC inhibitors with a quinazoline core. We demonstrate that this series can improve the translocation of GC to the lysosome in patient-derived cells. To optimize this chemical series, systematic synthetic modifications were performed and the SAR was evaluated and compared using three different readouts of compound activity: enzymatic inhibition, enzyme thermostabilization, and lysosomal translocation of GC.October 20, 2014
Published: Monday, Sept. 16, 2013 --- 8:50 p.m.
Every Monday night, Leo Endres and his wife Joyce come out to the VFW on Cottage Grove for chip night. But on this particular evening of drinks and conversation with friends, Endres can't help but think about the morning's tragic events at the Washington Navy Yard.
"You got feelings for all of them," Endres said. "You get feelings for any troops that, even regular Navy or not, that we've been there and done that. And it's sad that something's got to happen like this here."
A veteran of the U.S. Navy, Endres joined the military at 17, just after high school graduation.
"I spent a little over 16 months in Guam," he said. "Then I was transferred to a submarine rescue ship. And we spent six months out at sea and then we came back in."
Endres says he was shocked to turn on the news Monday, and hear about a gunman opening fire on the men and women with the same job title as him.
"You know, hopefully it wasn't a fellow Navy veteran who turned on his own people," Endres said. "That's all you can hope."
It was confirmed Monday that the Navy Yard gunman, Aaron Alexis, 34, was a member of the Navy.Vivo is known to be taking things to a whole new level and this time, the company has introduced us with Vivo V15 Pro – world’s first smartphone to carry 32MP pop-up selfie camera. For unawares, the smartphone has been making headlines for more than 3 months and we saw countless leaks and reports about this handset popping from all around the world.
The smartphone has been priced at INR 28,990 and is officially said to be available through Amazon and company’s own online store. The handset will be available at both places starting from 6th of March, 2019.
Built around a 6.39 inch full HD+ (sAMOLED Ultra FullView) display, the smartphone comes with nearly no bezels, 91.64 percent screen-to-body ratio, and 2340×1080 pixels of resolution. Powering the handset is Qualcomm’s Snapdragon 710 processor which comes coupled with 6GB of RAM and 128GB of ROM. As of now, we don’t know whether the internal storage is expandable.
Coming to the most important point, the Vivo V15 Pro comes with triple rear camera setup comprised of 48MP Quad Pixel sensor offering 12 million pixels, 8MP wide-angle lens, and 5MP depth sensor. It also features a 32MP pop-up front facing camera and as the name suggests, it pops out only when you switch from rear to front camera in camera interface. The handset is backed by a 3700 mAh battery with dual-engine fast charging support.
Talking about the features of Vivo V15 Pro, it runs on Android 8.1 Oreo-based company’s proprietary FunTouch OS. It features an in-display fingerprint sensor as well as facial recognition system for better security options. With a dedicated Google Assistant key, the handset comes with USB Type-C port, GPS with GLONASS, dual-SIM, Wi-Fi, Bluetooth 5.0, and 4G with VoLTE in connectivity options.
The post World’s First Smartphone with 32MP Pop-Up Selfie Camera – Vivo V15 Pro Launched in India appeared first on Hinglish News.Find your future at National Beef!
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“I didn't want (anyone to) ever question if he deserved it,” his father said.
The boy took the advice to heart. At 12, Kevin became CPR-certified, and at 18, he qualified as an EMT. He took fire-technology classes at Los Alamitos High School and Santa Ana College before graduating from El Camino Fire Academy in Torrance and training with the Cal Fire Academy in San Luis Obispo.
By the time he joined the Granite Mountain Hotshots, he had served as a seasonal employee with a wildfire crew in South Dakota. Joining the Arizona hotshot crew perfectly fit his brother's love for wild country, said Bobby Woyjeck, 19.
“He was like a kid in a candy store out there,” he said. “There were too many dirt trails for Kevin to know what to do with. He could get his Jeep stuck anywhere.”
His sister Maddie, 16, said she had too many good memories to describe. She said she struggles, however, when she thinks of the memories they won't have together: her graduation or becoming old enough to join him in country dancing at In Cahoots nightclub in Fullerton.
“Me and Kevin were supposed to do a lot of things together,” she said.
His beloved fishing boat has been passed on to a family friend, who gave it a new name: Hotshot.
As he closed the service, L.A. County Chaplain Paul Rusin read a message from the Granite Mountain Hotshots, describing the sacrifice and joy of working through each fire season.
“We do not just call ourselves hotshots,” Rusin said, pausing as he swallowed back tears. “We are hotshots in everything we.ethylene oxide sterilization for medical devices is suitable for sterilization of disposable sanitary products, medical supplies and medical devices.
1) Medical supplies: syringe, infusion device, dressing type, blood collection, catheter, birth control equipment, etc.
2) Medical devices: endoscope, pacemaker, artificial heart, oxygenator, etc.
3) Sanitary products: napkin, disposable sanitary tableware, etc.
4) Instruments: electronic instruments, optical instruments, recorder, telephone, etc.
door sealing way: air feeded inside.
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The touch screen cabinet installs the touch screen and the electronic control part for operation in a control cabinet. The system is not equipped with an industrial computer, and is used for occasions where the requirements are not high, and the price is relatively low.
Supply installation drawing.
Equipped installation and testing service.
Supply technical support all time.
Training how to operate the machine.
3)Sanitary products：Women's sanitary napkin, napkin, disposable sanitary tableware, etc.
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Kote Gauntlets developed in various forms going back to 12th Century Japan. By The 14th Century, they were an important piece of The Samurai Warriors protective gear. Designed to protect the fingers, hands and the complete arm (up to the elbow – Kote Gauntlets wer made of reinforced, heavy cloth or silk. Padded for comfort, only the palm was left open (to give grip to the Warriors sword or related weapon). Occasionally, raised metal studs were applied (but these were rare). Due to the length of the Sode Plating (from the shoulder), some protection was extended to this area as well. In some cases, Mail was used to cover The Kote.Fisherman Mayadhar Mallik Wiki: A fisherman was allegedly shot dead by the Coast Guard in the deep sea while he was fishing in the Gahirmartha area in the district on Friday night.
The deceased was identified