 large for the recessed holes. I went to Lowe's and got 1/4" gear and will get back at it on the next nice day.
OK, still haven't done the doors yet, waiting for warmer weather, but the center speaker in the dash is an 8 ohm speaker from the factory. There are no aftermarket 8 ohm 3.5" speakers on the market, so I will be leaving that one as factory installed. This is on the standard system, not the HK system.
Promotion officials announced the lightweight contest on Wednesday. UFC 203 takes place at Quicken Loans Arena in Cleveland on Sept. 10 and is headlined by a heavyweight title bout between Stipe Miocic and Alistair Overeem.
Taisumov has dispatched his last four foes in devastating fashion, scoring successive KO/TKO wins over Damir Hadzovic, Alan Patrick Silva Alves, Anthony Christodoulou and Marcin Bandel. “Beckan” is 5-1 in the UFC overall and 25-5 over the course of a professional career that began in 2007. Twenty-three of his victories have come inside the distance.
After a stint at featherweight, Lentz returned to 155 pounds at UFC on Fox 17, where he garnered a split decision against Danny Castillo. “The Carny” is 10-4-1 during his promotional tenure with wins over the likes of Manny Gamburyan, Hacran Dias, Diego Nunes and Tyson Griffin.
The highest-priced drugs have two things in common: they all treat rare diseases, and they all cost hundreds of thousands of dollars per year. A report posted on the Motley Fool website lists the world’s seven most-expensive drugs and the companies that profit from them.
Glybera (alipogen tiparvovec) is a gene therapy for adults with familial lipoprotein lipase deficiency, a rare genetic disorder that causes fat to accumulate in the blood. The drug, which won European approval in October 2012, costs more than $1 million per year. The FDA requested additional clinical trials before it would review Glybera for approval, but the drug’s developer––Dutch pharma company Uniqure––decided not to move forward with those studies.
Ravicti (glycerol phenylbutyrate), a nitrogen-binding agent, is used to treat urea cycle disorders (UCDs)––genetic diseases that prevent the body from eliminating ammonia. The resulting buildup of the toxic substance can lead to brain damage and death. Horizon Pharma sells Ravicti at an annual cost of nearly $794,000.
Spinraza (nusinersen, Biogen) received FDA approval in December 2016 for use in patients with spinal muscular atrophy. The drug costs $750,000 for the first year of treatment, but the price tag drops to $375,000 thereafter because fewer injections are required in subsequent years.
Lumizyme (alglucosidase alfa, Sanofi) replaces a missing or deficient enzyme in patients with Pompe disease, a genetic disorder caused by the buildup of glycogen in cells. The drug costs more than $626,000 annually.
Like Ravicti, Carbaglu (carglumic acid) is used to treat patients with UCDs. Unlike Ravicti, however, Carbaglu specifically targets N-acetylglutamate synthetase deficiency. The drug’s developer, Recordati Rare Diseases, has set an annual price of $585,000.
Horizon Pharma, the maker of Ravicti, also markets Actimmune (interferon gamma-1b), a biologically manufactured protein, which is used to treat two rare genetic disorders: chronic granulomatous disease (CGD) and severe malignant osteopetrosis (SMO). The drug is priced at more than $572,000 per year.
Soliris (eculizumab, Alexion Pharmaceuticals) also treats two rare diseases: paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). The annual cost is nearly $543,000.
As of 2015, more than 90 other prescription drugs carried annual price tags of more than $100,000, according to the Motley Fool article. Five of them cost more than $400,000 per year––just behind the drugs that made the Top Seven list.
Source: Motley Fool; April 18, 2017.
My experience with CIMI as a child fostered my passion for the oceans and diving.
This led me to a career, my closest friends, and my wife. After I retired, the opportunity to return to Guided Discoveries and give back to a program that means so much to me and my family fills me with joy.
Disney and Pop Warner have finally signed the contract for the 2013 Pop Warner Championships. The dates are a little later this year (7th – 14th) and it made a real change in the December Disney World Crowd Calendar. Here is the updated version.
Our weather forecast is from Wordpress WeatherOur readers ask some great questions about:
What's the difference between Migraine abortive and rescue medications?
Here are some extra links for you:
- Anatomy of a Migraine
- Migraine and Headache Specialists - What's So Special?
- Patient Recommended Migraine and Headache Specialists
- Do you have questions? We have answers. Find the three places to ask questions on our Migraine Answers page.
Live well,
Make a difference... Donate to the 36 Million Migraine Campaign!
© Teri Robert, 2013.
Last updated August 7, 2013.
Published On: August.Ques:House Party is a 1990 American comedy film released by New Line Cinema. It stars Kid and Play of the popular hip hop duo Kid 'n Play and also stars Paul Anthony Bow-Legged Lou and B-Fine from Full Force and Robin Harris in his last film appearance (who died of a heart attack nine days after House Party was released). The film also starred Martin Lawrence Tisha Campbell A.J. Johnson Daryl Chill Mitchell and Gene Groove Allen (of Groove B. Given a list of categories: company, educational institution, artist, athlete, office holder, mean of transportation, building, natural place, village, animal, plant, album, film or written work, what category does the paragraph belong to?

Ans:Film
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Ques:Stachys affinis the Chinese artichoke chorogi knotroot artichoke betony or crosne is a perennial herbaceous plant of the family Lamiaceae. Its rhizome can be grown as a root vegetable. While the plant is easy to grow the tubers are small convoluted and indented so they are considered very tedious if not difficult to clean properly. The thin skin ranges from a pale beige to ivory-white colour. The flesh underneath under proper cultivation is white and tender. Given a list of categories: company, educational institution, artist, athlete, office holder, mean of transportation, building, natural place, village, animal, plant, album, film or written work, what category does the paragraph belong to?

Ans:Plant
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Ques:Devin (Persian: دوين‎ also Romanized as Devīn) is a village in Miyan Velayat Rural District in the Central District of Mashhad County Razavi Khorasan Province Iran. At the 2006 census its population was 359 in 90 families. Given a list of categories: company, educational institution, artist, athlete, office holder, mean of transportation, building, natural place, village, animal, plant, album, film or written work, what category does the paragraph belong to?

Ans:Village
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Ques:50th Birthday Celebration Volume 1 is a live album by the Masada String Trio documenting their performance at Tonic in September 2003 as part of John Zorn's month-long 50th Birthday Celebration concert series. Given a list of categories: company, educational institution, artist, athlete, office holder, mean of transportation, building, natural place, village, animal, plant, album, film or written work, what category does the paragraph belong to?

Ans:
Album
-----Hartford Stage is now accepting entries for the Young Playwrights for Change Competition. Young Playwrights for Change is a playwriting contest for middle school students. Students from Connecticut, Massachusetts, Rhode Island, Vermont, New Hampshire and Maine are invited to submit plays answering the question "What is Family?"
Hartford Stage will also be hosting a series of free writing workshops in January to help interested participants develop their ideas into 10-minute plays. Middle school students are welcome to attend any or all of the workshops. The workshops will be held at the Hartford Stage Education Center at 942 Main Street in Hartford. The top three plays will have a staged reading at Hartford Stage's Youth Studio.
Writing workshops will be held on the following dates:
• Saturday, January 3, 2015 from 2:00 - 4:00 pm
• Saturday, January 10, 2015 from 2:00 - 4:00 pm
• Saturday, January 17, 2015 from 2:00 - 4:00 pm
The deadline for final play submission is Wednesday, January 21, 2015. The winning play will be submitted to represent New England in the national Young Playwrights for Change competition hosted by Theatre for Young Audiences (TYA/USA) and American Alliance for Theatre and Education (AATE).
To download an entry form, register for a workshop, or get helpful writing tips, visit. For additional information, contact Ashley Baker, Resident Teaching Artist