Daily Papers

We present Chameleon, a family of early-fusion token-based mixed-modal models capable of understanding and generating images and text in any arbitrary sequence. We outline a stable training approach from inception, an alignment recipe, and an architectural parameterization tailored for the early-fusion, token-based, mixed-modal setting. The models are evaluated on a comprehensive range of tasks, including visual question answering, image captioning, text generation, image generation, and long-form mixed modal generation. Chameleon demonstrates broad and general capabilities, including state-of-the-art performance in image captioning tasks, outperforms Llama-2 in text-only tasks while being competitive with models such as Mixtral 8x7B and Gemini-Pro, and performs non-trivial image generation, all in a single model. It also matches or exceeds the performance of much larger models, including Gemini Pro and GPT-4V, according to human judgments on a new long-form mixed-modal generation evaluation, where either the prompt or outputs contain mixed sequences of both images and text. Chameleon marks a significant step forward in a unified modeling of full multimodal documents.

Large language models (LLMs) have achieved remarkable progress in solving various natural language processing tasks due to emergent reasoning abilities. However, LLMs have inherent limitations as they are incapable of accessing up-to-date information (stored on the Web or in task-specific knowledge bases), using external tools, and performing precise mathematical and logical reasoning. In this paper, we present Chameleon, an AI system that mitigates these limitations by augmenting LLMs with plug-and-play modules for compositional reasoning. Chameleon synthesizes programs by composing various tools (e.g., LLMs, off-the-shelf vision models, web search engines, Python functions, and heuristic-based modules) for accomplishing complex reasoning tasks. At the heart of Chameleon is an LLM-based planner that assembles a sequence of tools to execute to generate the final response. We showcase the effectiveness of Chameleon on two multi-modal knowledge-intensive reasoning tasks: ScienceQA and TabMWP. Chameleon, powered by GPT-4, achieves an 86.54% overall accuracy on ScienceQA, improving the best published few-shot result by 11.37%. On TabMWP, GPT-4-powered Chameleon improves the accuracy by 17.0%, lifting the state of the art to 98.78%. Our analysis also shows that the GPT-4-powered planner exhibits more consistent and rational tool selection via inferring potential constraints from instructions, compared to a ChatGPT-powered planner.

Large language models have evolved data-efficient generalists, benefiting from the universal language interface and large-scale pre-training. However, constructing a data-efficient generalist for dense visual prediction presents a distinct challenge due to the variation in label structures across different tasks. Consequently, generalization to unseen dense prediction tasks in the low-data regime is not straightforward and has received less attention from previous vision generalists. In this study, we explore a universal model that can flexibly adapt to unseen dense label structures with a few examples, enabling it to serve as a data-efficient vision generalist in diverse real-world scenarios. To this end, we base our method on a powerful meta-learning framework and explore several axes to improve its performance and versatility for real-world problems, such as flexible adaptation mechanisms and scalability. We evaluate our model across a spectrum of unseen real-world scenarios where low-shot learning is desirable, including video, 3D, medical, biological, and user-interactive tasks. Equipped with a generic architecture and an effective adaptation mechanism, our model flexibly adapts to all of these tasks with at most 50 labeled images, showcasing a significant advancement over existing data-efficient generalist approaches. Codes are available at https://github.com/GitGyun/chameleon.

The integration of machine learning (ML) in numerous critical applications introduces a range of privacy concerns for individuals who provide their datasets for model training. One such privacy risk is Membership Inference (MI), in which an attacker seeks to determine whether a particular data sample was included in the training dataset of a model. Current state-of-the-art MI attacks capitalize on access to the model's predicted confidence scores to successfully perform membership inference, and employ data poisoning to further enhance their effectiveness. In this work, we focus on the less explored and more realistic label-only setting, where the model provides only the predicted label on a queried sample. We show that existing label-only MI attacks are ineffective at inferring membership in the low False Positive Rate (FPR) regime. To address this challenge, we propose a new attack Chameleon that leverages a novel adaptive data poisoning strategy and an efficient query selection method to achieve significantly more accurate membership inference than existing label-only attacks, especially at low FPRs.

In a federated learning (FL) system, distributed clients upload their local models to a central server to aggregate into a global model. Malicious clients may plant backdoors into the global model through uploading poisoned local models, causing images with specific patterns to be misclassified into some target labels. Backdoors planted by current attacks are not durable, and vanish quickly once the attackers stop model poisoning. In this paper, we investigate the connection between the durability of FL backdoors and the relationships between benign images and poisoned images (i.e., the images whose labels are flipped to the target label during local training). Specifically, benign images with the original and the target labels of the poisoned images are found to have key effects on backdoor durability. Consequently, we propose a novel attack, Chameleon, which utilizes contrastive learning to further amplify such effects towards a more durable backdoor. Extensive experiments demonstrate that Chameleon significantly extends the backdoor lifespan over baselines by 1.2times sim 4times, for a wide range of image datasets, backdoor types, and model architectures.

Conversational participants tend to immediately and unconsciously adapt to each other's language styles: a speaker will even adjust the number of articles and other function words in their next utterance in response to the number in their partner's immediately preceding utterance. This striking level of coordination is thought to have arisen as a way to achieve social goals, such as gaining approval or emphasizing difference in status. But has the adaptation mechanism become so deeply embedded in the language-generation process as to become a reflex? We argue that fictional dialogs offer a way to study this question, since authors create the conversations but don't receive the social benefits (rather, the imagined characters do). Indeed, we find significant coordination across many families of function words in our large movie-script corpus. We also report suggestive preliminary findings on the effects of gender and other features; e.g., surprisingly, for articles, on average, characters adapt more to females than to males.

By providing external information to large language models (LLMs), tool augmentation (including retrieval augmentation) has emerged as a promising solution for addressing the limitations of LLMs' static parametric memory. However, how receptive are LLMs to such external evidence, especially when the evidence conflicts with their parametric memory? We present the first comprehensive and controlled investigation into the behavior of LLMs when encountering knowledge conflicts. We propose a systematic framework to elicit high-quality parametric memory from LLMs and construct the corresponding counter-memory, which enables us to conduct a series of controlled experiments. Our investigation reveals seemingly contradicting behaviors of LLMs. On the one hand, different from prior wisdom, we find that LLMs can be highly receptive to external evidence even when that conflicts with their parametric memory, given that the external evidence is coherent and convincing. On the other hand, LLMs also demonstrate a strong confirmation bias when the external evidence contains some information that is consistent with their parametric memory, despite being presented with conflicting evidence at the same time. These results pose important implications that are worth careful consideration for the further development and deployment of tool- and retrieval-augmented LLMs.

Large language models (LLMs) often appear to excel on public benchmarks, but these high scores may mask an overreliance on dataset-specific surface cues rather than true language understanding. We introduce the Chameleon Benchmark Overfit Detector (C-BOD), a meta-evaluation framework that systematically distorts benchmark prompts via a parametric transformation and detects overfitting of LLMs. By rephrasing inputs while preserving their semantic content and labels, C-BOD exposes whether a model's performance is driven by memorized patterns. Evaluated on the MMLU benchmark using 26 leading LLMs, our method reveals an average performance degradation of 2.15% under modest perturbations, with 20 out of 26 models exhibiting statistically significant differences. Notably, models with higher baseline accuracy exhibit larger performance differences under perturbation, and larger LLMs tend to be more sensitive to rephrasings indicating that both cases may overrely on fixed prompt patterns. In contrast, the Llama family and models with lower baseline accuracy show insignificant degradation, suggesting reduced dependency on superficial cues. Moreover, C-BOD's dataset- and model-agnostic design allows easy integration into training pipelines to promote more robust language understanding. Our findings challenge the community to look beyond leaderboard scores and prioritize resilience and generalization in LLM evaluation.

The development of large language models (LLMs) has expanded to multi-modal systems capable of processing text, images, and speech within a unified framework. Training these models demands significantly larger datasets and computational resources compared to text-only LLMs. To address the scaling challenges, we introduce Mixture-of-Transformers (MoT), a sparse multi-modal transformer architecture that significantly reduces pretraining computational costs. MoT decouples non-embedding parameters of the model by modality -- including feed-forward networks, attention matrices, and layer normalization -- enabling modality-specific processing with global self-attention over the full input sequence. We evaluate MoT across multiple settings and model scales. In the Chameleon 7B setting (autoregressive text-and-image generation), MoT matches the dense baseline's performance using only 55.8\% of the FLOPs. When extended to include speech, MoT reaches speech performance comparable to the dense baseline with only 37.2\% of the FLOPs. In the Transfusion setting, where text and image are trained with different objectives, a 7B MoT model matches the image modality performance of the dense baseline with one third of the FLOPs, and a 760M MoT model outperforms a 1.4B dense baseline across key image generation metrics. System profiling further highlights MoT's practical benefits, achieving dense baseline image quality in 47.2\% of the wall-clock time and text quality in 75.6\% of the wall-clock time (measured on AWS p4de.24xlarge instances with NVIDIA A100 GPUs).

We present CM3Leon (pronounced "Chameleon"), a retrieval-augmented, token-based, decoder-only multi-modal language model capable of generating and infilling both text and images. CM3Leon uses the CM3 multi-modal architecture but additionally shows the extreme benefits of scaling up and tuning on more diverse instruction-style data. It is the first multi-modal model trained with a recipe adapted from text-only language models, including a large-scale retrieval-augmented pre-training stage and a second multi-task supervised fine-tuning (SFT) stage. It is also a general-purpose model that can do both text-to-image and image-to-text generation, allowing us to introduce self-contained contrastive decoding methods that produce high-quality outputs. Extensive experiments demonstrate that this recipe is highly effective for multi-modal models. CM3Leon achieves state-of-the-art performance in text-to-image generation with 5x less training compute than comparable methods (zero-shot MS-COCO FID of 4.88). After SFT, CM3Leon can also demonstrate unprecedented levels of controllability in tasks ranging from language-guided image editing to image-controlled generation and segmentation.

State Space Models (SSMs) have emerged as efficient alternatives to Transformers for sequential modeling, but their inability to leverage modality-specific features limits their performance in multi-modal pretraining. Here, we propose Mixture-of-Mamba, a novel SSM architecture that introduces modality-aware sparsity through modality-specific parameterization of the Mamba block. Building on Mixture-of-Transformers (W. Liang et al. arXiv:2411.04996; 2024), we extend the benefits of modality-aware sparsity to SSMs while preserving their computational efficiency. We evaluate Mixture-of-Mamba across three multi-modal pretraining settings: Transfusion (interleaved text and continuous image tokens with diffusion loss), Chameleon (interleaved text and discrete image tokens), and an extended three-modality framework incorporating speech. Mixture-of-Mamba consistently reaches the same loss values at earlier training steps with significantly reduced computational costs. In the Transfusion setting, Mixture-of-Mamba achieves equivalent image loss using only 34.76% of the training FLOPs at the 1.4B scale. In the Chameleon setting, Mixture-of-Mamba reaches similar image loss with just 42.50% of the FLOPs at the 1.4B scale, and similar text loss with just 65.40% of the FLOPs. In the three-modality setting, MoM matches speech loss at 24.80% of the FLOPs at the 1.4B scale. Our ablation study highlights the synergistic effects of decoupling projection components, where joint decoupling yields greater gains than individual modifications. These results establish modality-aware sparsity as a versatile and effective design principle, extending its impact from Transformers to SSMs and setting new benchmarks in multi-modal pretraining. Our code can be accessed at https://github.com/Weixin-Liang/Mixture-of-Mamba

Previous open-source large multimodal models (LMMs) have faced several limitations: (1) they often lack native integration, requiring adapters to align visual representations with pre-trained large language models (LLMs); (2) many are restricted to single-modal generation; (3) while some support multimodal generation, they rely on separate diffusion models for visual modeling and generation. To mitigate these limitations, we present Anole, an open, autoregressive, native large multimodal model for interleaved image-text generation. We build Anole from Meta AI's Chameleon, adopting an innovative fine-tuning strategy that is both data-efficient and parameter-efficient. Anole demonstrates high-quality, coherent multimodal generation capabilities. We have open-sourced our model, training framework, and instruction tuning data.

Large Language Models (LLMs) have marked a significant advancement in the field of natural language processing, demonstrating exceptional capabilities in reasoning, tool usage, and memory. As their applications extend into multi-agent environments, a need has arisen for a comprehensive evaluation framework that captures their abilities in reasoning, planning, collaboration, and more. This work introduces a novel benchmarking framework specifically tailored to assess LLMs within multi-agent settings, providing quantitative metrics to evaluate their judgment, reasoning, deception, self-awareness, cooperation, coordination, and rationality. We utilize games such as Chameleon and Undercover, alongside game theory scenarios like Cost Sharing, Multi-player Prisoner's Dilemma, and Public Good, to create diverse testing environments. Our framework is fortified with the Probabilistic Graphical Modeling (PGM) method, enhancing the LLMs' capabilities in navigating complex social and cognitive dimensions. The benchmark evaluates seven multi-agent systems powered by different LLMs, quantitatively highlighting a significant capability gap over threefold between the strongest, GPT-4, and the weakest, Llama-2-70B. It also confirms that our PGM enhancement boosts the inherent abilities of all selected models by 50% on average. Our codes are released here https://github.com/cathyxl/MAgIC.

The advancement of Large Language Models(LLMs) has brought substantial attention to the Chain of Thought(CoT) approach, primarily due to its ability to enhance the capability of LLMs on tasks requiring complex reasoning. Moreover, the significance of CoT approaches extends to the application of LLMs for multi-modal tasks, such as multi-modal question answering. However, the selection of optimal CoT demonstration examples in multi-modal reasoning for LLMs remains less explored for LLMs due to the inherent complexity of multi-modal examples. In this paper, we introduce a novel approach that addresses this challenge by using retrieval mechanisms to dynamically and automatically select demonstration examples based on cross-modal similarities. This method aims to refine the CoT reasoning process in multi-modal scenarios via informing LLMs with more relevant and informative examples. Furthermore, we employ a stratified sampling method categorising demonstration examples into groups based on their types and retrieving examples from different groups respectively to promote the diversity of demonstration examples. Through a series of experiments, we demonstrate that our approach significantly improves the performance of LLMs, achieving state-of-the-art results in multi-modal reasoning tasks. Specifically, our methods demonstrate significant advancements on the ScienceQA dataset. While our method based on ChatGPT outperforms the Chameleon(ChatGPT) by 2.74% with an accuracy of 82.67%, the GPT4-based approach surpasses the Chameleon(GPT-4) by 0.89%, achieving 87.43% on accuracy under the same setting. Moreover, our best performing show a 6.05% increase over Chameleon for ChatGPT-based models and a 4.57% increase for GPT-4-based models.

With the rise of large language models (LLMs), ensuring they embody the principles of being helpful, honest, and harmless (3H), known as Human Alignment, becomes crucial. While existing alignment methods like RLHF, DPO, etc., effectively fine-tune LLMs to match preferences in the preference dataset, they often lead LLMs to highly receptive human input and external evidence, even when this information is poisoned. This leads to a tendency for LLMs to be Adaptive Chameleons when external evidence conflicts with their parametric memory. This exacerbates the risk of LLM being attacked by external poisoned data, which poses a significant security risk to LLM system applications such as Retrieval-augmented generation (RAG). To address the challenge, we propose a novel framework: Dialectical Alignment (DA), which (1) utilizes AI feedback to identify optimal strategies for LLMs to navigate inter-context conflicts and context-memory conflicts with different external evidence in context window (i.e., different ratios of poisoned factual contexts); (2) constructs the SFT dataset as well as the preference dataset based on the AI feedback and strategies above; (3) uses the above datasets for LLM alignment to defense poisoned context attack while preserving the effectiveness of in-context knowledge editing. Our experiments show that the dialectical alignment model improves poisoned data attack defense by 20 and does not require any additional prompt engineering or prior declaration of ``you may be attacked`` to the LLMs' context window.

With the rapid development of generative models, discerning AI-generated content has evoked increasing attention from both industry and academia. In this paper, we conduct a sanity check on "whether the task of AI-generated image detection has been solved". To start with, we present Chameleon dataset, consisting AIgenerated images that are genuinely challenging for human perception. To quantify the generalization of existing methods, we evaluate 9 off-the-shelf AI-generated image detectors on Chameleon dataset. Upon analysis, almost all models classify AI-generated images as real ones. Later, we propose AIDE (AI-generated Image DEtector with Hybrid Features), which leverages multiple experts to simultaneously extract visual artifacts and noise patterns. Specifically, to capture the high-level semantics, we utilize CLIP to compute the visual embedding. This effectively enables the model to discern AI-generated images based on semantics or contextual information; Secondly, we select the highest frequency patches and the lowest frequency patches in the image, and compute the low-level patchwise features, aiming to detect AI-generated images by low-level artifacts, for example, noise pattern, anti-aliasing, etc. While evaluating on existing benchmarks, for example, AIGCDetectBenchmark and GenImage, AIDE achieves +3.5% and +4.6% improvements to state-of-the-art methods, and on our proposed challenging Chameleon benchmarks, it also achieves the promising results, despite this problem for detecting AI-generated images is far from being solved. The dataset, codes, and pre-train models will be published at https://github.com/shilinyan99/AIDE.

With the introduction of transformer-based models for vision and language tasks, such as LLaVA and Chameleon, there has been renewed interest in the discrete tokenized representation of images. These models often treat image patches as discrete tokens, analogous to words in natural language, learning joint alignments between visual and human languages. However, little is known about the statistical behavior of these visual languages - whether they follow similar frequency distributions, grammatical structures, or topologies as natural languages. In this paper, we take a natural-language-centric approach to analyzing discrete visual languages and uncover striking similarities and fundamental differences. We demonstrate that, although visual languages adhere to Zipfian distributions, higher token innovation drives greater entropy and lower compression, with tokens predominantly representing object parts, indicating intermediate granularity. We also show that visual languages lack cohesive grammatical structures, leading to higher perplexity and weaker hierarchical organization compared to natural languages. Finally, we demonstrate that, while vision models align more closely with natural languages than other models, this alignment remains significantly weaker than the cohesion found within natural languages. Through these experiments, we demonstrate how understanding the statistical properties of discrete visual languages can inform the design of more effective computer vision models.

We introduce Orthus, an autoregressive (AR) transformer that excels in generating images given textual prompts, answering questions based on visual inputs, and even crafting lengthy image-text interleaved contents. Unlike prior arts on unified multimodal modeling, Orthus simultaneously copes with discrete text tokens and continuous image features under the AR modeling principle. The continuous treatment of visual signals minimizes the information loss for both image understanding and generation while the fully AR formulation renders the characterization of the correlation between modalities straightforward. The key mechanism enabling Orthus to leverage these advantages lies in its modality-specific heads -- one regular language modeling (LM) head predicts discrete text tokens and one diffusion head generates continuous image features conditioning on the output of the backbone. We devise an efficient strategy for building Orthus -- by substituting the Vector Quantization (VQ) operation in the existing unified AR model with a soft alternative, introducing a diffusion head, and tuning the added modules to reconstruct images, we can create an Orthus-base model effortlessly (e.g., within mere 72 A100 GPU hours). Orthus-base can further embrace post-training to better model interleaved images and texts. Empirically, Orthus surpasses competing baselines including Show-o and Chameleon across standard benchmarks, achieving a GenEval score of 0.58 and an MME-P score of 1265.8 using 7B parameters. Orthus also shows exceptional mixed-modality generation capabilities, reflecting the potential for handling intricate practical generation tasks.

Node classification is a classical graph machine learning task on which Graph Neural Networks (GNNs) have recently achieved strong results. However, it is often believed that standard GNNs only work well for homophilous graphs, i.e., graphs where edges tend to connect nodes of the same class. Graphs without this property are called heterophilous, and it is typically assumed that specialized methods are required to achieve strong performance on such graphs. In this work, we challenge this assumption. First, we show that the standard datasets used for evaluating heterophily-specific models have serious drawbacks, making results obtained by using them unreliable. The most significant of these drawbacks is the presence of a large number of duplicate nodes in the datasets Squirrel and Chameleon, which leads to train-test data leakage. We show that removing duplicate nodes strongly affects GNN performance on these datasets. Then, we propose a set of heterophilous graphs of varying properties that we believe can serve as a better benchmark for evaluating the performance of GNNs under heterophily. We show that standard GNNs achieve strong results on these heterophilous graphs, almost always outperforming specialized models. Our datasets and the code for reproducing our experiments are available at https://github.com/yandex-research/heterophilous-graphs

In this paper, we introduce Janus, an autoregressive framework that unifies multimodal understanding and generation. Prior research often relies on a single visual encoder for both tasks, such as Chameleon. However, due to the differing levels of information granularity required by multimodal understanding and generation, this approach can lead to suboptimal performance, particularly in multimodal understanding. To address this issue, we decouple visual encoding into separate pathways, while still leveraging a single, unified transformer architecture for processing. The decoupling not only alleviates the conflict between the visual encoder's roles in understanding and generation, but also enhances the framework's flexibility. For instance, both the multimodal understanding and generation components can independently select their most suitable encoding methods. Experiments show that Janus surpasses previous unified model and matches or exceeds the performance of task-specific models. The simplicity, high flexibility, and effectiveness of Janus make it a strong candidate for next-generation unified multimodal models.

We present Autoregressive Representation Alignment (ARRA), a new training framework that unlocks global-coherent text-to-image generation in autoregressive LLMs without architectural changes. Unlike prior work that requires complex architectural redesigns, ARRA aligns LLM hidden states with visual representations from external visual foundational models via a global visual alignment loss and a hybrid token, <HYBNEXT>. This token enforces dual constraints: local next-token prediction and global semantic distillation, enabling LLMs to implicitly learn spatial and contextual coherence while retaining their original autoregressive paradigm. Extensive experiments validate ARRA's plug-and-play versatility. When training from text-generation-only LLMs or random initialization, ARRA reduces FID by 25.5% (MIMIC-CXR), 8.8% (DeepEyeNet), and 7.5% (ImageNet) for advanced autoregressive LLMs like Chameleon and LlamaGen, all without framework modifications. For domain adaption, ARRA aligns general-purpose LLMs with specialized models (e.g., BioMedCLIP), achieving an 18.6% FID reduction over direct fine-tuning on medical imaging (MIMIC-CXR). By demonstrating that training objective redesign -- not just architectural innovation -- can resolve cross-modal global coherence challenges, ARRA offers a complementary paradigm for advancing autoregressive models. Code and models will be released to advance autoregressive image generation.

We present Liquid, an auto-regressive generation paradigm that seamlessly integrates visual comprehension and generation by tokenizing images into discrete codes and learning these code embeddings alongside text tokens within a shared feature space for both vision and language. Unlike previous multimodal large language model (MLLM), Liquid achieves this integration using a single large language model (LLM), eliminating the need for external pretrained visual embeddings such as CLIP. For the first time, Liquid uncovers a scaling law that performance drop unavoidably brought by the unified training of visual and language tasks diminishes as the model size increases. Furthermore, the unified token space enables visual generation and comprehension tasks to mutually enhance each other, effectively removing the typical interference seen in earlier models. We show that existing LLMs can serve as strong foundations for Liquid, saving 100x in training costs while outperforming Chameleon in multimodal capabilities and maintaining language performance comparable to mainstream LLMs like LLAMA2. Liquid also outperforms models like SD v2.1 and SD-XL (FID of 5.47 on MJHQ-30K), excelling in both vision-language and text-only tasks. This work demonstrates that LLMs such as LLAMA3.2 and GEMMA2 are powerful multimodal generators, offering a scalable solution for enhancing both vision-language understanding and generation. The code and models will be released.

Camouflaged objects that blend into natural scenes pose significant challenges for deep-learning models to detect and synthesize. While camouflaged object detection is a crucial task in computer vision with diverse real-world applications, this research topic has been constrained by limited data availability. We propose a framework for synthesizing camouflage data to enhance the detection of camouflaged objects in natural scenes. Our approach employs a generative model to produce realistic camouflage images, which can be used to train existing object detection models. Specifically, we use a camouflage environment generator supervised by a camouflage distribution classifier to synthesize the camouflage images, which are then fed into our generator to expand the dataset. Our framework outperforms the current state-of-the-art method on three datasets (COD10k, CAMO, and CHAMELEON), demonstrating its effectiveness in improving camouflaged object detection. This approach can serve as a plug-and-play data generation and augmentation module for existing camouflaged object detection tasks and provides a novel way to introduce more diversity and distributions into current camouflage datasets.

Recent advancements in mixed-modal generative models have enabled flexible integration of information across image-text content. These models have opened new avenues for developing unified biomedical assistants capable of analyzing biomedical images, answering complex questions about them, and predicting the impact of medical procedures on a patient's health. However, existing resources face challenges such as limited data availability, narrow domain coverage, and restricted sources (e.g., medical papers). To address these gaps, we present MedMax, the first large-scale multimodal biomedical instruction-tuning dataset for mixed-modal foundation models. With 1.47 million instances, MedMax encompasses a diverse range of tasks, including multimodal content generation (interleaved image-text data), biomedical image captioning and generation, visual chatting, and report understanding. These tasks span diverse medical domains such as radiology and histopathology. Subsequently, we fine-tune a mixed-modal foundation model on the MedMax dataset, achieving significant performance improvements: a 26% gain over the Chameleon model and an 18.3% improvement over GPT-4o across 12 downstream biomedical visual question-answering tasks. Additionally, we introduce a unified evaluation suite for biomedical tasks, providing a robust framework to guide the development of next-generation mixed-modal biomedical AI assistants.

While Graph Neural Networks have gained popularity in multiple domains, graph-structured input remains a major challenge due to (a) over-smoothing, (b) noisy neighbours (heterophily), and (c) the suspended animation problem. To address all these problems simultaneously, we propose a novel graph neural network FDGATII, inspired by attention mechanism's ability to focus on selective information supplemented with two feature preserving mechanisms. FDGATII combines Initial Residuals and Identity Mapping with the more expressive dynamic self-attention to handle noise prevalent from the neighbourhoods in heterophilic data sets. By using sparse dynamic attention, FDGATII is inherently parallelizable in design, whist efficient in operation; thus theoretically able to scale to arbitrary graphs with ease. Our approach has been extensively evaluated on 7 datasets. We show that FDGATII outperforms GAT and GCN based benchmarks in accuracy and performance on fully supervised tasks, obtaining state-of-the-art results on Chameleon and Cornell datasets with zero domain-specific graph pre-processing, and demonstrate its versatility and fairness.