Taiyi: A Bilingual Fine-Tuned Large Language Model for Diverse Biomedical Tasks

Recent advancements in large language models (LLMs) have shown promising results across a variety of natural language processing (NLP) tasks. The application of LLMs to specific domains, such as biomedicine, has achieved increased attention. However, most biomedical LLMs focus on enhancing performance in monolingual biomedical question answering and conversation tasks. To further investigate the effectiveness of the LLMs on diverse biomedical NLP tasks in different languages, we present Taiyi, a bilingual (English and Chinese) fine-tuned LLM for diverse biomedical tasks. In this work, we first curated a comprehensive collection of 140 existing biomedical text mining datasets across over 10 task types. Subsequently, a two-stage strategy is proposed for supervised <PRE_TAG>fine-tuning</POST_TAG> to optimize the model performance across varied tasks. Experimental results on 13 test sets covering named entity recognition, relation extraction, text <PRE_TAG>classification</POST_TAG>, question answering tasks demonstrate Taiyi achieves superior performance compared to general LLMs. The case study involving additional biomedical NLP tasks further shows Taiyi's considerable potential for <PRE_TAG>bilingual biomedical multi-tasking</POST_TAG>. The source code, datasets, and model for Taiyi are freely available at https://github.com/DUTIR-BioNLP/Taiyi-LLM.