---
tags:
  - text-classification
  - transformers
  - biobert
  - miRNA
  - biomedical
  - LoRA
  - fine-tuning
library_name: transformers
datasets:
  - custom-biomedical-dataset
license: apache-2.0
---

# 🧬 miRNA-BioBERT: Fine-Tuned BioBERT for miRNA Sentence Classification  
**Fine-tuned BioBERT model for classifying miRNA-related sentences in biomedical research papers.**  

<!-- 🔗 **Hugging Face Model Link**: [debjit20504/miRNA-biobert](https://huggingface.co/debjit20504/miRNA-biobert)   -->

---

## 📌 Overview  
**miRNA-BioBERT** is a fine-tuned version of [BioBERT](https://huggingface.co/dmis-lab/biobert-base-cased-v1.1), trained specifically for **classifying sentences** as **miRNA-related (relevant) or not (irrelevant)**. The model is useful for **automating literature reviews**, **extracting relevant sentences**, and **identifying key insights** in genomic research.  

✔ **Base Model**: `dmis-lab/biobert-base-cased-v1.1`  
✔ **Fine-tuning Method**: **LoRA (Low-Rank Adaptation)**  
✔ **Dataset**: **Curated biomedical text corpus containing labeled miRNA-relevant and non-relevant sentences**  
✔ **Task**: **Binary classification (1 = functional, 0 = non-functional)**  
✔ **Trained on**: **RTX A6000 GPU (5 epochs, batch size 32, learning rate 2e-5)**  

## 🚀 How to Use the Model  
### 1️⃣ Install Dependencies  
```bash  
pip install transformers torch
```
```python
from transformers import AutoModelForSequenceClassification, AutoTokenizer  
import torch  

# Load the model and tokenizer  
model_name = "debjit20504/miRNA-biobert"  
tokenizer = AutoTokenizer.from_pretrained(model_name)  
model = AutoModelForSequenceClassification.from_pretrained(model_name)  

# Move model to GPU or MPS (for Mac)  
device = torch.device("mps") if torch.backends.mps.is_available() else torch.device("cuda" if torch.cuda.is_available() else "cpu")  
model.to(device)  
model.eval()

def classify_text(text):  
    inputs = tokenizer(text, return_tensors="pt").to(device)  
    with torch.no_grad():  
        output = model(**inputs)  
        label = torch.argmax(output.logits, dim=1).item()  
    return "functional" if label == 1 else "Non-functional"  

# Example Test  
sample_text = "The results showed that miR-223-3p decreased in glioblastoma tissue but NLRP3 increased."  
print(f"Classification: {classify_text(sample_text)}")  
```

## 📊 Training Details
- Dataset: Biomedical text dataset with 429,785 relevant sentences and 87,966 irrelevant sentences.
- Fine-Tuning Method: LoRA (Low-Rank Adaptation) for efficient training.
- Training Hardware: NVIDIA RTX A6000 GPU.
- Training Settings:
    - Batch size: 32
    - Learning rate: 2e-5
    - Optimizer: AdamW
    - Warmup steps: 1000
    - Epochs: 5
    - Mixed precision (fp16): ✅ Enabled for efficiency.

---

## 📖 Model Applications  
✅ **Biomedical NLP** – Extracting meaningful information from biomedical literature.  
✅ **miRNA Research** – Identifying sentences discussing miRNA mechanisms.  
✅ **Automated Literature Review** – Filtering relevant studies efficiently.  
✅ **Genomics & Bioinformatics** – Enhancing data retrieval from scientific texts.  

---

## 📬 Contact
For any questions or collaborations, reach out via:  

**📧 Email**: debjit.pramanik@postgrad.manchester.ac.uk  
**🔗 LinkedIn**: https://www.linkedin.com/in/debjit-pramanik-88a837171/