Possible Side Effects of JANUMET® (sitagliptin and metformin HCl) tablets
Important Information About the Possible Side Effects of JANUMET
1.Lactic Acidosis. Metformin, one of the medicines in JANUMET, can cause a rare but serious condition called lactic acidosis (a buildup of an acid in the blood) that can cause death. Lactic acidosis is a medical emergency and must be treated in the hospital.
JANUMET can have other serious side effects. See “What are the possible side effects of JANUMET?”
Before you start taking JANUMET, tell your doctor if you have ever had heart failure or have problems with your kidneys. Contact your doctor right away if you have any of the following symptoms:
are allergic to any of the ingredients in JANUMET. See the end of the Medication Guide for a complete list of ingredients in JANUMET.
See above section: "What is the most important information I should know about JANUMET?"
Serious allergic reactions. If you have any symptoms of a serious allergic reaction, stop taking JANUMET and call your doctor right away or get emergency medical help. See above section: "Who should not take JANUMET?". Your doctor may give you a medicine for your allergic reaction and prescribe a different medicine for your diabetes.
JANUMET may have other side effects, including swelling of the hands or legs. Swelling of the hands and legs can happen if you take JANUMET in combination with rosiglitazone (Avandia®). Rosiglitazone is another type of diabetes medicine