Abstracts: XXIII Annual Conference of the Indian Pharmacological Society held at Bombay from 6th to 8th December, 1990 p. 1
Adverse reactions to gentamicin p. 64
KC Singhal, Verma Kamini, Kumar Pramod, RS Bhatia
1. Adverse drug reactions (ADR) following gentamicin administration were studied. 2. The ADR profile obtained was nephrotoxicity (3 46%), ototoxicity (5 49%), pruritic skin rash (0.99%) and psychotic reaction (0.49%) The overall incidence of ADR being 8.41%. 3. An attempt was made to identify the risk factors predisposing to the development of renal toxicity due to gentamicin.Apparent higher incidences were obtained in male patients in ages over 50 years,with duration of therapy of 10 days or more, with simultaneous use of cephalosporins and with pre-existing hypovolemia and hypotension. Only advanced age (over 50 years) was found to be statistically significant.
Serum and Urinary lead levels in hypertension p. 69
S Bhardwaj, O Chandra, AS Khan
1. A one year longitudinal study was conducted on 200 hypertensive patients, aged 25-55 years. 50 healthy volunteers, age and sex matched served as control. The mean serum and 24 hrs urinary lead levels were determined by Double Beam Atomic Absorption Spectrophotometery. 2. The mean serum lead level was higher in hypertensive patients as compared to control (p