Browsing Magister Scientiae - MSc (Biotechnology) by Title
Signalling molecule “calcium” improves germination and growth of Sorghum bicolor seedlings under salt stress ﻿
Hendricks, Kaylin (University of the Western Cape, 2021)
Abiotic stress, mainly in the form of extreme temperatures, drought and salinity has caused major crop losses worldwide, putting a severe strain on agriculture. Salinity severely limits plant growth and productivity and ...
Silica Coated Core-Shell Quantum Dot-based Electro-Immunosensor for Interferon Gamma TB Disease Biomarker ﻿
Mini, Sixolile (University of the Western Cape, 2020)
Tuberculosis (TB) is a disease that results from infection by Mycobacterium tuberculosis, which is regarded the most common infecting organism. TB has killed countless numbers of people particularly in underdeveloped ...
Single nucleotide polymorphism association studies of ABCA13 and ABHD11 genes and the bioinformatics analysis of the autism candidate genes localized on chromosome 7 ﻿
Spartial distribution of cyanobacterial phylotypes in Antarctic Dry Valley soil biotopes ﻿
Keyster, Marshall (University of the Western Cape, 2007)
Recent advances in moleculr methods have enabled the analysis of cyanobacterial diversity using PCR- based approaches. Snap-shot techniques such as 16S rDNA library construction and DGGE have allowed for increased access ...
SSR-based genetic mapping of QTLs determining chilling requirements for time of initial vegetative budbreak in domesticated apple (Malus x domestica Borkh.) cultivar ‘Anna’ x ‘Austin’ ﻿
Hove, Paidashe (University of the Western Cape, 2012)
The Rosaceae family contains major temperate crops such as the domesticated apple(Malus x domestica Borkh.), peach (Prunus persica L. Batsch) and European pear (Pyrus communis L.). However, despite its evident economic ...
Structural analysis of induced mutagenesis A’ protein from mycobacterium tuberculosis and of a thermophillic GH9 cellulase ﻿
Anye, Valentine (University of the Western Cape, 2014)
The three-dimensional structures of proteins are important in understanding their function and interaction with ligands and other proteins. In this work, the structures of two proteins, ImuA’ from mycobacterium tuberculosis ...
Structural Analysis of Induced Mutagenesis Protein B from Mycobacterium tuberculosis Jeremy ﻿
Boonzaier, Jeremy (University of the Western Cape, 2016)
Knowing the three-dimensional structure of a protein may be useful in understanding its function. In this study, induced mutagenesis protein B (ImuB) from Mycobacterium tuberculosis was analyzed using molecular biology and ...
The structure of the nitrilase from Rhodococcus Rhodochrous J1: homology modeling and three-dimensional reconstruction ﻿
Thuku, Robert Ndoria (University of the Western Cape, 2006)
The nitrilases are an important class of industrial enzymes that are found in all phyla. These enzymes are expressed widely in prokaryotes and eukaryotes. Nitrilases convert nitriles to corresponding acids and ammonia. ...
The structure, function and engineering of a thermostable nitrile hydratase ﻿
Mavengere, William Nyasha (University of the Western Cape, 2008)
Nitrile hydratases (NHases) are enzymes that catalyse the conversion of organocyanides to amides via a non-hydrolytic hydration reaction. They are industrially relevant enzymes, currently used in the manufacture of ...
Synthesis of silver doped titanium dioxide nanocomposites using tea extract from Aspalathus linearis and evaluation of their antibacterial effects. ﻿
Kobese, Nokubonga (University of the Western Cape, 2018)
Despite the wide success of antimicrobial agents against waterborne pathogens, waterborne disease continues to pose a threat to both mankind and animals. A major concern is that certain bacteria have developed resistance ...
Synthesis of silver nanoparticles and investigating their antimicrobial effects ﻿
Sithole, Zimasa N. (University of the Western Cape, 2015)
Water is essential for life, yet access to safe drinking water is still a major concern worldwide due to waterborne diseases. The current study proposes silver nanoparticles (AgNPs) as an antibacterial agent. Silver ...
Systematic approach to protein crystallization: emphasis on Vaccinia virus complement control protein (VCP) ﻿
Adusei-Danso, Felix (University of the Western Cape, 2006)
This work examined the systematic approach to protein crystallization, exploring some of the techniques that have been developed to enhance the success rate of crystallization. The work was centered on two proteins; namely ...
Targeted delivery of embelin to cancer cells ﻿
Emjedi, Zaakiyah Z. (University of the Western Cape, 2013)
Apoptosis or programmed cell death is vital to the development of organisms as they maintain the balance between cell death and cell growth. Failure to activate apoptosis has been implicated in carcinogenesis and often ...
Targeted delivery of GFP loaded polymeric nanoparticles to CD4 expressing cells using a CD4 specific aptamer ﻿
Mirfin, Tayla Michele (University of the Western Cape, 2020)
Human Immunodeficiency Virus (HIV), which is the cause of Acquired Immunodefiency Syndrome (AIDS) is a major global public health issue affecting over 37 million people worldwide and is responsible for claiming over 32 ...
The effect of exogenous DIM on Brassica napus and its role in response to heavy metal stress ﻿
Roode, Enrico Carlo (University of the Western Cape, 2017)
Brassica napus is a plant that is used for human and animal consumption. This plant is also used for phytoremediation due to its relatively higher level of heavy metal tolerance. In South Africa, mining is one of the main ...
The inhibition of nitric oxide biosynthesis alters anti-oxidant capacity in soybean ﻿
Le Keur, Julian André (University of the Western Cape, 2016)
Nitric oxide is a signalling gaseous molecule endogenously synthesized from various enzymatic and non-enzymatic sources in plants. It is known to play a crucial role in the regulation of plant physiological processes ...
The molecular validation of miRNA's as specific biomarkers for early diagnosis of ovarian cancer ﻿
Lottering, Sharneal (University of the Western Cape, 2017)
Ovarian Cancer (OC) is the most common reproductive and the most lethal gynaecological malignant tumour. The majority of Ovarian Cancers, comprising more than 95% of cases, emanate from the surface epithelium of the ovary, ...
The safety and toxicity of MPA-CdTe quantum dots in legume plants ﻿
Omar, Zaahira (University of the Western Cape, 2017)
The expansion of nanotechnology, resulting in multitudes of consumer and industrial products, causes concern amongst the scientific community regarding the risks associated with the release of nanomaterials into the ...
Using biochemical and nutrient analysis to understand the role of methylglyoxal signalling in soybean exposed to zirconium ﻿
Ndlovu, L.E.G (University of the Western Cape, 2017)
Soybean have been listed as a priority commodity crop in South Africa (SA) and provide a good source of protein to the population. Therefore, soybean has been earmarked as an important food security crop and strategies are ...
Ndlovu, Linda Esihle (University of the Western Cape, 2017)
Soybean have been listed as a priority commodity crop in South Africa (SA) and provide a good source of protein to the population. Therefore, soybean has been earmarked as an important food security crop and strategies ...