(-) subject:"Type\ 2\ diabetes"
Searched for: subject:"Type%5C+2%5C+diabetes"
Tans, R. (author), Verschuren, L. (author), Wessels, H.J.C.T. (author), Bakker, S.J.L. (author), Tack, C.J. (author), Gloerich, J. (author), van Gool, A.J. (author)
Introduction: The onset of type 2 diabetes mellitus (T2DM) is strongly associated with obesity and subsequent perturbations in immuno-metabolic responses. To understand the complexity of these systemic changes and better monitor the health status of people at risk, validated clinical biomarkers are needed. Omics technologies are increasingly...
van Ommen, B. (author), Wopereis, S. (author), van Empelen, P. (author), van Keulen, H.M. (author), Otten, W. (author), Kasteleyn, M. (author), Molema, J.J.W. (author), de Hoogh, I.M. (author), Chavannes, N.H. (author), Numans, M.E. (author), Evers, A.W.M. (author), Pijl, H. (author)
From a biological view, most of the processes involved in insulin resistance, which drives the pathobiology of type 2 diabetes, are reversible. This theoretically makes the disease reversible and curable by changing dietary habits and physical activity, particularly when adopted early in the disease process. Yet, this is not fully implemented...
Alcohol consumption, lifestyle factors, and type 2 diabetes
Stricker, M.D. (author), Hendriks, H.F.J. (author), Beulens, J.W.J. (author)
Castiglione, F. (author), Tieri, P. (author), de Graaf, A.A. (author), Franceschi, C. (author), Liò, P. (author), van Ommen, B. (author), Mazzà, C. (author), Tuchel, A. (author), Bernaschi, M. (author), Samson, C. (author), Colombo, T. (author), Castellani, G.C. (author), Capri, M. (author), Garagnani, P. (author), Salvioli, S. (author), Nguyen, V.A. (author), Bobeldijk-Pastorova, I. (author), Krishnan, S. (author), Cappozzo, A. (author), Sacchetti, M. (author), Morettini, M. (author), Ernst, M. (author)
Background: Type 2 diabetes mellitus (T2D) is a common age-related disease, and is a major health concern, particularly in developed countries where the population is aging, including Europe. The multi-scale immune system simulator for the onset of type 2 diabetes (MISSION-T2D) is a European Union-funded project that aims to develop and validate...
Urinary matrix metalloproteinase-8 and -9 activities in type 2 diabetic subjects: A marker of incipient diabetic nephropathy?
van der Zijl, N.J. (author), Hanemaaijer, R. (author), Tushuizen, M.E. (author), Schindhelm, R.K. (author), Boerop, J. (author), Rustemeijer, C. (author), Bilo, H.J. (author), Verheijen, J.H. (author), Diamant, M. (author), TNO Kwaliteit van Leven (author)
Matrix metalloproteinases (MMPs) may play a pathophysiological role in the development of diabetic nephropathy (DN). We hypothesized that urinary MMP activity in patients with type 2 diabetes mellitus (T2DM) is related to a decline in renal function. We determined MMP-2, -8 and -9 activity in 24-h urine collections in relation to risk factors...
Eating behaviour and adherence to diet in patients with Type 2 diabetes mellitus
van de Laar, F.A. (author), van de Lisdonk, E.H. (author), Lucassen, P.L.B.J. (author), Stafleu, A. (author), Mulder, J. (author), van den Hoogen, H.J.M. (author), Rutten, G.E.H.M. (author), van Weel, C. (author), TNO Kwaliteit van Leven (author)
Aims: To assess restrained, emotional and external eating behaviour in patients newly diagnosed with Type 2 diabetes compared with the general population, and to assess the relationship of eating behaviour to changes in fat and energy. Methods: We assessed emotional, external, and restrained eating behaviour and measured fat and energy intake in...