How accurate is the group A beta-hemolytic streptococcal (GABHS) rapid antigen detection test for the diagnosis of pharyngitis (sore throat)?
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Antigens are specific, but sensitivities vary. The sensitivity of the GABHS rapid antigen detection test is 70-90%, and the specificity is 90-100%, depending on the manufacturer. [23, 24, 25, 26] Children with a negative antigen test should have a follow-up culture unless the antigen being used in the office has been shown to be as sensitive as a culture. [17]