This book focuses upon a particular type of entrepreneurship, called knowledge intensive entrepreneurship, which is defined and analyzed through a model proposed here. One main message is that entrepreneurship is a phenomenon that may be thought of as structured and defined processes - as taught with business planning - but also one involving high levels of uncertainty and risk due to the nature of knowledge involved in this type. This book proposes a new model for the creation of this type of ventures, based upon a richer understanding of the interactions between the company and hte external environment for opportunities and knowledge.