SARS-CoV-2 disrupts timing of immune response – BioNews Central
SARS-CoV-2 disrupts timing of immune response. Credit: © Ugreen - Depositphotos
The researchers began by isolating NK cells from the blood of men and women who had developed COVID-19 of varying degrees of severity. This was followed by functional analysis in the laboratory. Subsequent comparison with cells isolated from both healthy donors and patients with other severe respiratory diseases showed that NK cells are able to recognize and kill SARS-CoV-2-infected lung tissue cells. Furthermore, the decrease in throat viral load was found to be particularly rapid in individuals whose blood had shown large numbers of these immune cells at the beginning of their SARS-CoV-2 infection. “In short, NK cells help the body fight SARS-CoV-2,” explains Dr. Witkowski. “According to our laboratory tests, however, cells isolated from patients with severe disease were far less effective against the virus than cells taken from individuals with mild symptoms.”
Materials provided by Charité – Universitätsmedizin Berlin. Content may be edited for clarity, style, and length.e
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