PreSENTIA Hereditary |Genetic Cancer Test Leeds Yorkshire
PreSENTIA Hereditary Cancer Tests
PreSENTIA Hereditary Cancer Tests £550
PreSENTIA hereditary cancer test panels by NIPD Genetics can detect numerous inherited genetic changes (mutations) that could cause cancer in the future.
NIPD Genetics is a leading innovative biotechnology company active in the field of developing, engineering and providing in vitro genetic testing solutions. NIPD Genetics laboratories are accredited by CAP and certified by CLIA and ISO standards and provide SAFE , ACCURATE and RELIABLE in vitro genetic testing services internationally. https://www.nipd.com/products/oncology/presentia/
PreSENTIA offers an extensive portfolio of 19 Hereditary cancer test panels. Each panel focuses on a set of genes that determine someone’s chances of developing specific cancer in the future. The genetic changes in the genes that could cause cancer are inherited from parents to their children and are present from birth. Knowing that a person carries one of these genetic mutations can help them take preventative measures and plan more informed clinical management. As a result, early detection of cancer can be achieved – which increases the chances of successful treatment – or prevention
According to genetic testing guidelines, people who might benefit from genetic testing for hereditary cancers are those that have:
Several family members in the same side of the family with cancer
Multiple cancers in the same family member
Family members with early cancer onset
Family members with rare cancer types
Family members with an unusual type of cancer (breast cancer in a male)
Personal or family history of a hereditary cancer syndrome
A family member that has been diagnosed with a germline mutation associated with cancer susceptibility
History of previous malignancies
HOW does PreSENTIA HELP you?
PreSENTIA panels test for numerous genetic changes that are responsible for causing hereditary cancers. If you want to know more about your cancer risks, or if you have been already diagnosed with cancer and you want to know whether your cancer is hereditary, PreSENTIA can help.
Targeted cancer monitoring – recommended screening tests at key time intervals to detect cancer early, when treatment is more beneficial
Prevention of cancer by prophylactic measures
Actionable information for family members that might carry the same gene
Improved classification of the disease for better clinical management
Drug therapy (chemoprevention)
WHY CHOOSE THE PreSENTIA TEST?
Assesses clinically important mutations
Ability to select the best panel for you
Various PreSENTIA hereditary cancer test panels:
PreSENTIA Hereditary Breast / Gynaecological cancer panel - £ 575
Hereditary Breast/Gynecological cancer panel tests for numerous germline mutations that could cause Breast, Ovarian or Endometrial cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
No of Genes Tested : 26
Disorders that are related with this Panel : 12
The genes that are not linked with hereditary cancer syndrome but are associated with cancer risk, and are also analyzed by this panel:
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PreSENTIA Hereditary Breast / Gynaecological guidelines-based - £575
Hereditary Breast/Gynecological cancer guidelines-based panel tests for numerous germline mutations that could cause Breast, Ovarian, Endometrial or associated cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
Disorders that are related with this Panel : 9
Ataxia telangiectasia syndrome (ATM)
The following genes are not linked with a hereditary cancer syndrome but are associated with cancer risk, and are also analyzed by this panel:
PreSENTIA Hereditary Breast High-Risk - £550
Hereditary Breast High-Risk cancer panel tests for numerous germline mutations that are associated with a high risk for developing Breast, Ovarian, Endometrial or associated cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
No of Genes Tested : 7
Disorders associated with this panel : 5
Peutz-Jeughers syndrome (STK11)
PreSENTIA Hereditary BRCA1/BRCA2 cancer panel - £ 304
Hereditary BRCA1/BRCA2 cancer panel tests for germline mutations in the BRCA1 and BRCA2 genes that could cause specific cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
Disorders associated with this panel: 1
PreSENTIA Hereditary Colorectal cancer panel - £ 575
Hereditary Colorectal cancer panel tests for numerous germline mutations that could cause colorectal cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
Disorders associated with this panel:12
PreSENTIA Hereditary Colorectal High-Risk cancer panel - £ 550
Hereditary Colorectal High-Risk cancer panel tests for numerous germline mutations that could cause colorectal cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
PreSENTIA Hereditary Colorectal Non-Polyposis cancer panel - £ 550
PreSENTIA Hereditary Colorectal Polyposis syndrome cancer panel - £ 550
Hereditary Colorectal Polyposis cancer panel tests for numerous germline mutations that could cause colorectal cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
PreSENTIA Hereditary Myelodysplastic syndrome / Leukaemia cancer panel - £ 625
Hereditary Myelodysplastic syndrome / Leukemia cancer panel tests for numerous germline mutations that could cause blood cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for hereditary myelodysplastic syndromes or leukemias are those that have:
Family history of a hereditary cancer syndrome associated with leukemia
Personal history of a hereditary cancer syndrome associated with leukemia
An identical twin who developed leukemia in the first year of life
Hereditary breast & ovarian syndrome (BRCA1 & BRCA2)
PreSENTIA Hereditary Gastric cancer panel - £ 575
Hereditary Gastric cancer panel tests for numerous inherited germline mutations that could cause gastric (stomach) cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for gastric cancers are those that have:
Several family members in the same side of the family with gastric cancer
Personal or family history of a hereditary cancer syndrome linked to gastric cancer
Hereditary Paraganglioma-Pheochromocytoma syndrome (SDHB, SDHC, SDHD)
PreSENTIA Hereditary Prostate cancer panel - £ 575
Hereditary Prostate cancer panel tests for numerous germline mutations that could cause prostate cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
PreSENTIA Hereditary Pancreatic cancer panel - £ 575
Hereditary Pancreatic cancer panel tests for numerous germline mutations that could cause pancreatic cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for pancreatic cancers are those that have:
Several family members in the same side of the family with pancreatic cancer
First-degree relative who developed pancreatic cancer before the age of 50
Personal or family history of a hereditary cancer syndrome linked to pancreatic cancer
Disorders associated with this panel: 10
PreSENTIA Hereditary Renal cancer panel - £ 575
Hereditary Renal cancer panel tests for numerous germline mutations that could cause renal (kidney) cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
PreSENTIA Hereditary Skin (Xeroderma-Pigmentosum) cancer panel - £ 575
Hereditary Xeroderma Pigmentosum-related cancer panel tests for numerous germline mutations that could cause skin cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for Xeroderma Pigmentosum-related skin cancers are those that have:
Family or personal history of a hereditary cancer syndrome associated with skin cancers
PreSENTIA Hereditary Familial Melanoma cancer panel - £ 575
Hereditary Familial Melanoma cancer panel tests for numerous germline mutations that could cause familial melanoma skin cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for hereditary melanoma cancers are those that have:
At least two first-degree family member who have had metastatic melanoma
At least one family member has had multiple melanomas
Family or personal history of a hereditary cancer syndrome associated with melanoma
Hereditary pancreatic-melanoma syndrome (CDKN2A, CDK4)
PreSENTIA Hereditary Paraganglioma/ / Pheochromocytoma cancer panel - £ 575
Hereditary Paraganglioma / Pheochromocytoma cancer panel tests for germline mutations in numerous genes that could cause Paraganglioma or Pheochromocytoma cancer in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for Paraganglioma or Pheochromocytoma cancers are those that have:
Family or personal history of a hereditary cancer syndrome associated with paraganglioma / pheochromocytoma cancers
Hereditary Paraganglioma – Pheochromocytoma syndrome (SDHAF2, SDHB, SDHD, SDHC)
PreSENTIA Hereditary Parathyroid cancer panel - £ 550
Hereditary Parathyroid cancer panel tests for germline mutations in the MEN1 gene that could cause parathyroid cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
According to genetic testing guidelines, people who might benefit from genetic testing for parathyroid cancers are those that have:
At least two first-degree family member who have had parathyroid tumors
A personal or family history of a hereditary cancer syndrome associated with parathyroid cancer
PreSENTIA Hereditary Thyroid cancer panel - £ 550
Hereditary Thyroid cancer panel tests for germline mutations in the RET gene that could cause medullary thyroid cancer in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
At least one first-degree family member who has had thyroid cancer
A personal or family history of a hereditary cancer syndrome associated with thyroid cancer
PreSENTIA Hereditary Pan-Cancer panel - £ 950
Hereditary Pan-Cancer panel tests for numerous germline mutations in a total of 62 genes that could cause several cancers in the future. Identifying germline mutations associated with cancer susceptibility empowers healthcare providers and patients, as it allows them to take better and more informed decisions.
For More information please visit NIPD Genetics
NIPD Genetics is a leading innovative biotechnology company active in the field of developing, engineering and providing in vitro genetic testing solutions. NIPD Genetics laboratories are accredited by CAP and certified by CLIA and ISO standards and provide SAFE , ACCURATE and RELIABLE in vitro genetic testing services internationally.
https://www.nipd.com/products/oncology/presentia/
TARGETED TECHNOLOGY - By focusing only on the genetic changes tested, PreSENTIA is accurate and precise.
HIGH READ DEPTH - PreSENTIA analyzes the locations of the genetic changes hundreds of times, making the test results more sensitive and reliable.
Are you interested in PreSENTIA test? Here’s it how it works
CONSULT WITH YOUR HEALTHCARE PROVIDER ON WHICH PANEL IS IDEAL FOR YOU
Our health care professionals will collect a buccal swab sample from you
The sample will be sent to NIPD's laboratory
The sample will be analyzed at NIPD's laboratory
Cancer is the rapid and uncontrollable growth of abnormal cells. It is the second leading cause of death, responsible for 1 out of 6 deaths globally. World Health Organization (WHO) recommends that cancer mortality can be significantly reduced by early detection and proper clinical management of cancers.
Cancer develops after certain genes that are responsible for keeping our body healthy undergo changes that cause them to become ‘faulty’. A cancer can be: ***. SPORADIC: Mutations in the genes causing cancer accumulate over time due to risk factors like tobacco, viruses (such as HPV), and environmental factors. These mutations cannot be inherited. ***. HEREDITARY: These mutations exist from birth. They run in families and can be passed down from parents to their children *** Inherited genetic mutations make up for 5-10% of all cancers.
What are Germline Mutations?
Germline mutations are changes in the DNA that are inherited from parents to their children. These changes are present from birth in all the cells in the body. People with germline mutations in a cancer gene have a higher chance of developing cancer in their lifetime. If cancer develops due to a germline mutation, it is called hereditary cancer.
What is a Hereditary Screening Test?
A Hereditary Screening test checks if an individual has an inherited gene mutation in a gene with high cancer susceptibility. If you or a family member were diagnosed with hereditary cancer, or a genetic change that is linked to cancer, there's a high chance other members of your family carry the genetic change as well. Each individual could be affected by cancer at different age, with wide range of severity, and by different cancer types.
What is cancer susceptibility and cancer predisposition?
Cancer susceptibility, or predisposition, is the likelihood of being affected by cancer in the future. This depends on an individual’s DNA. There are certain inherited, genetic changes that raise someone’s risk of developing cancer in the future. This is because these changes happen in genes that are responsible for protecting the body from disease, and when they are affected, their protective role halts.
Identifying the genetic change that could cause cancer in the future is useful for people with cancer in their family history, and for people suspected of having a hereditary form of cancer. This knowledge can help with better medical planning, avoiding risk factors and informing family members of their risk. According to genetic testing guidelines* for cancer, people who might benefit from genetic testing are those that have Family members with cancer in the same side of the family , Multiple cancers in the same family member , Family members with early cancer onset , Family members with rare cancer types , A family member that has been diagnosed with a genetic mutation that has cancer susceptibility and Personal or family history of a hereditary cancer syndrome
WHAT ARE ‘HEREDITARY CANCER SYNDROMES’?
Hereditary cancer syndromes are also known as cancer predisposing syndromes, as patients with these syndromes have an elevated risk of developing specific cancers in the future. These conditions occur when genes with critical roles in keeping our body healthy are mutated, causing a variety of symptoms and potentially affecting the quality of life. They can be inherited from one generation to the other.
Hereditary cancer syndromes characteristics
Repeated cancers
Young age of cancer onset
If you have cancer in your family history and want to know about your own risk, PreSENTIA can help. By identifying the mutated genes that could cause hereditary cancer syndromes, PreSENTIA can provide information that could help in clinical management. If you have been diagnosed with cancer and have any of the above characteristics, you might also have a hereditary cancer syndrome. Identifying this can help reveal how and why your cancer was caused.
Book now to reserve your spot for Hereditary Cancer Screening Leeds
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