Examining the role of glia signaling in neuronal excitability
Lead Researcher(s): Erin Gray
Understanding how glia regulate the expression and/or post-translational modification of sodium ion channels may lead to the identification of new pharmaceutical targets for the treatment of pain.
Kinetic determinants of GPCR signaling: from ultra-fast to diffusion-limited
Lead Researcher(s): Rabindra Shivnaraine
G protein-coupled receptors (GPCRs) are proteins that exist within the cell membrane and act to transfer the information encoded within neurotransmitters and drugs into cell responses. GPCRs exist throughout the body in several systems including the nervous system.
Transcriptomic analysis of neural circuits activated during encoding of long-term memory
Lead Researcher(s): Boxuan Zhao
Our ability to remember makes us human, and is essential for acquiring new skills and integrating previous experiences into future decision-making. While it is known that long-term memory (LTM) formation requires new gene expression, we lack a detailed and comprehensive understanding of which genes...