Which pathophysiological change seen in critically ill patients most frequently makes medication dosage adjustment necessary?
A. Decreased plasma protein binding Wrong Choice!
B. Decreased renal clearance Correct Choice
C. Diminished GI or subcutaneous perfusion Wrong Choice!
D. Inhibition of hepatic enzymes Wrong Choice!
Answer:B
Which pathophysiological change seen in critically ill patients most frequently makes medication dosage adjustment necessary?
A. Decreased plasma protein binding Wrong Choice! B. Decreased renal clearance Correct Choice C. Diminished GI or subcutaneous perfusion Wrong Choice! D. Inhibition of hepatic enzymes Wrong Choice!