A 52-year-old woman is admitted to the ICU, who is s/p orthotopic liver transplant 2 weeks ago, for septic shock requiring vasopressor support. Pertinent past medical history includes an unprovoked pulmonary embolism 3 months ago for which she takes apixaban 5 mg twice daily at home. Review of systems reveals normal renal function, active bowel sounds with two recent bowel movements, and a Glasgow Coma Score of 15. In the presence of distributive shock requiring vasopressor support, with regard to absorption, which scheduled medications would you be most concerned about?
A. Subcutaneous enoxaparin Correct Choice
B. Sublingual tacrolimus Wrong Choice!
C. Intravenous hydrocortisone Wrong Choice!
D. Oral mycophenolate Wrong Choice!
Answer:A
A 52-year-old woman is admitted to the ICU, who is s/p orthotopic liver transplant 2 weeks ago, for septic shock requiring vasopressor support. Pertinent past medical history includes an unprovoked pulmonary embolism 3 months ago for which she takes apixaban 5 mg twice daily at home. Review of systems reveals normal renal function, active bowel sounds with two recent bowel movements, and a Glasgow Coma Score of 15. In the presence of distributive shock requiring vasopressor support, with regard to absorption, which scheduled medications would you be most concerned about?
A. Subcutaneous enoxaparin Correct Choice B. Sublingual tacrolimus Wrong Choice! C. Intravenous hydrocortisone Wrong Choice! D. Oral mycophenolate Wrong Choice!