A computer program recognizes an ORF by looking for ribosomal binding sites, start codons, and stop codons with an appropriate number of nucleotides between each element. What is a drawback of this approach?
A. Too many ORFS are identified, most of which are stretches on non-coding junk DNA.
B. Codon bias causes incorrect annotations.
C. Unusual, but legitimate genes and non-coding RNA may be missed.
D. We lack the computing power to complete the analyses in a timely manner, thus many genomes are only partially annotated.
Answer:C
A computer program recognizes an ORF by looking for ribosomal binding sites, start codons, and stop codons with an appropriate number of nucleotides between each element. What is a drawback of this approach?
A. Too many ORFS are identified, most of which are stretches on non-coding junk DNA. B. Codon bias causes incorrect annotations. C. Unusual, but legitimate genes and non-coding RNA may be missed. D. We lack the computing power to complete the analyses in a timely manner, thus many genomes are only partially annotated.