Which of the following statements is false regarding Glomerulonephritis associated with Complement Disorders ?
A. Enhanced surface C3 activation underlies the pathogenesis of atypical Haemolytic Uraemic Syndrome (aHUS)
B. Enhanced plasma C3 activation is typically seen in Dense Deposit Disease (DDD)
C. C3 Nephritic Factor (C3NeF) is present in the majority of patients C3 glomerulonephritis and approximately 50% of patients with DDD
D. Up to 80% of patients with DDD and up to half of the patients with C3GN have low levels of serum C3
Answer:C
Which of the following statements is false regarding Glomerulonephritis associated with Complement Disorders ?
A. Enhanced surface C3 activation underlies the pathogenesis of atypical Haemolytic Uraemic Syndrome (aHUS) B. Enhanced plasma C3 activation is typically seen in Dense Deposit Disease (DDD) C. C3 Nephritic Factor (C3NeF) is present in the majority of patients C3 glomerulonephritis and approximately 50% of patients with DDD D. Up to 80% of patients with DDD and up to half of the patients with C3GN have low levels of serum C3