An 18-year-old male with multiple stab wounds to his abdomen is brought by ambulance to the trauma bay. He is bleeding profusely, with HR 128 beats/min, BP 72/41 mm Hg, SpO2 92% on 15 L oxygen via nonrebreathing face mask. Of the following statements regarding this patient’s renin-angiotensin-aldosterone system (RAAS), which is FALSE?
A. Decreased oxygenation in the macula densa activates the RAAS Correct Choice
B. Increased conversion of angiotensin I to II via renin results in angiotensin (AT1)-receptor–mediated vasoconstriction of arteriolar smooth muscle Wrong Choice!
C. Angiotensin II has a greater effect on efferent glomerular arterioles than afferent, preserving glomerular pressure Wrong Choice!
D. Aldosterone release promotes sodium and water retention in the kidneys leading to greater volume retention Wrong Choice!
Answer:A
An 18-year-old male with multiple stab wounds to his abdomen is brought by ambulance to the trauma bay. He is bleeding profusely, with HR 128 beats/min, BP 72/41 mm Hg, SpO2 92% on 15 L oxygen via nonrebreathing face mask. Of the following statements regarding this patient’s renin-angiotensin-aldosterone system (RAAS), which is FALSE?
A. Decreased oxygenation in the macula densa activates the RAAS Correct Choice B. Increased conversion of angiotensin I to II via renin results in angiotensin (AT1)-receptor–mediated vasoconstriction of arteriolar smooth muscle Wrong Choice! C. Angiotensin II has a greater effect on efferent glomerular arterioles than afferent, preserving glomerular pressure Wrong Choice! D. Aldosterone release promotes sodium and water retention in the kidneys leading to greater volume retention Wrong Choice!