A 48-year-old female with family history of pheochromocytoma is undergoing laparoscopic nephrectomy for newly diagnosed renal cell carcinoma. The surgeons note an adrenal mass not previously seen on imaging, and manipulation of the kidney causes severe hypertension up to 225/135 mm Hg. The case is aborted, with the patient transferred to the intensive care unit for blood pressure management. In this scenario, which of the following biochemical testing is most recommended?
A. 24-hour urine catecholamines Wrong Choice!
B. Plasma catecholamines Wrong Choice!
C. 24-hour urine-fractionated metanephrines Wrong Choice!
D. Plasma-fractionated metanephrines Correct Choice
Answer:D
A 48-year-old female with family history of pheochromocytoma is undergoing laparoscopic nephrectomy for newly diagnosed renal cell carcinoma. The surgeons note an adrenal mass not previously seen on imaging, and manipulation of the kidney causes severe hypertension up to 225/135 mm Hg. The case is aborted, with the patient transferred to the intensive care unit for blood pressure management. In this scenario, which of the following biochemical testing is most recommended?
A. 24-hour urine catecholamines Wrong Choice! B. Plasma catecholamines Wrong Choice! C. 24-hour urine-fractionated metanephrines Wrong Choice! D. Plasma-fractionated metanephrines Correct Choice