Which of the following statements regarding TNFa are true?
A. TNFa has a marked procoagulant effect
B. Passive immunization of patients with neutralizing antibodies to TNFa improves survival from multi-organ system failure
C. TNFa upregulates E-selectin expression
D. The most potent known stimulus for TNFa production and release is IL-1
Answer:A
Which of the following statements regarding TNFa are true?
A. TNFa has a marked procoagulant effect B. Passive immunization of patients with neutralizing antibodies to TNFa improves survival from multi-organ system failure C. TNFa upregulates E-selectin expression D. The most potent known stimulus for TNFa production and release is IL-1