As compared with the early immunosuppressive drugs (azathioprine, steroids, antilymphocyte serum) some newer agents have the following specific advantages:
A. Cyclosporine, which interferes with lymphokine production, exhibits neither bone marrow nor renal toxicity.
B. Monoclonal antibody (OKT3) is more available and has greater specificity and fewer side effects than antilymphocyte serum.
C. Tacrolimus (FK506) has properties similar to those of cyclosporine but is especially valuable for rescue of grafts that are failing on cyclosporine therapy.
D. None of the above.
Answer:C
As compared with the early immunosuppressive drugs (azathioprine, steroids, antilymphocyte serum) some newer agents have the following specific advantages:
A. Cyclosporine, which interferes with lymphokine production, exhibits neither bone marrow nor renal toxicity. B. Monoclonal antibody (OKT3) is more available and has greater specificity and fewer side effects than antilymphocyte serum. C. Tacrolimus (FK506) has properties similar to those of cyclosporine but is especially valuable for rescue of grafts that are failing on cyclosporine therapy. D. None of the above.