Which of the following statements regarding fibroblasts and their function in wound healing are true?
A. IL-1 has both inhibitory and promotional effects on fibroblast growth
B. TNFa stimulates fibroblast collagen synthesis
C. IL-1 and TNFa have opposite effects on the healing of bone
D. In human clinical trials, EGF (epithelial growth factor) has been demonstrated to accelerate epidermal regeneration in cutaneous wounds
Answer:A
Which of the following statements regarding fibroblasts and their function in wound healing are true?
A. IL-1 has both inhibitory and promotional effects on fibroblast growth B. TNFa stimulates fibroblast collagen synthesis C. IL-1 and TNFa have opposite effects on the healing of bone D. In human clinical trials, EGF (epithelial growth factor) has been demonstrated to accelerate epidermal regeneration in cutaneous wounds