Which of the following signal transduction mechanisms is associated with T cell activation and has been shown to be inhibited by immunosuppressive agents such as cyclosporin A?
A. activation of protein tryrosine kinases
B. activation of transcription factors (e.g. NF-kB, NFAT)s
C. activation of PLC-gl
D. calcium mobilization
Answer:B
Which of the following signal transduction mechanisms is associated with T cell activation and has been shown to be inhibited by immunosuppressive agents such as cyclosporin A?
A. activation of protein tryrosine kinases B. activation of transcription factors (e.g. NF-kB, NFAT)s C. activation of PLC-gl D. calcium mobilization