A 39-year-old woman with embolic occlusion of an iliac artery is subject to an operating room delay before perfusion can be restored. The following is/are true:
A. Ischemia for longer than 3 hours will result in muscle fiber autolysis
B. Earliest ultrastructural changes of ischemia in muscle include mitochondrial swelling and loss of glycogen granules
C. Phosphocreatine mediated rephosphorylation of ADP occurs for about 3 hours after ischemia
D. Capillary thrombosis is the most likely explanation for the “no-reflow” phenomenon
Answer:B
A 39-year-old woman with embolic occlusion of an iliac artery is subject to an operating room delay before perfusion can be restored. The following is/are true:
A. Ischemia for longer than 3 hours will result in muscle fiber autolysis B. Earliest ultrastructural changes of ischemia in muscle include mitochondrial swelling and loss of glycogen granules C. Phosphocreatine mediated rephosphorylation of ADP occurs for about 3 hours after ischemia D. Capillary thrombosis is the most likely explanation for the “no-reflow” phenomenon