Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following statement(s) is/are true concerning antimicrobial classes?
A. Penicillins and cephalosporins share the compound structure of a b-lactam ring which binds to bacterial division plate proteins
B. Tetracyclines and macrolides such as erythromycin inhibit bacterial ribosomal activity and therefore protein synthesis
C. Aminoglycosides act in a similar fashion to tetracyclines and therefore are both bacteriostatic
D. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis
Answer:A
Antibacterial agents can be classified with regard to their structure, mechanism of action, and activity pattern against various types of bacterial pathogens. Which of the following statement(s) is/are true concerning antimicrobial classes?
A. Penicillins and cephalosporins share the compound structure of a b-lactam ring which binds to bacterial division plate proteins B. Tetracyclines and macrolides such as erythromycin inhibit bacterial ribosomal activity and therefore protein synthesis C. Aminoglycosides act in a similar fashion to tetracyclines and therefore are both bacteriostatic D. Sulfonamides and trimethoprim act synergistically to inhibit purine synthesis