Which of the following statements describes the role of transcription factors (TF) in hematopoiesis?
A. TF expression does not change during hematopoiesis.
B. TF function either to activate or suppress target gene expression.
C. TF block the differentiation pathway for hematopoietic precursors.
D. TF abnormalities are rarely seen in hematologic malignancies.
Answer:B
Which of the following statements describes the role of transcription factors (TF) in hematopoiesis?
A. TF expression does not change during hematopoiesis. B. TF function either to activate or suppress target gene expression. C. TF block the differentiation pathway for hematopoietic precursors. D. TF abnormalities are rarely seen in hematologic malignancies.