Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because
A. it is displaced from the heme by oxygen
B. it is displaced from the heme by movement of the proximal histidine
C. its binding pocket becomes too small to accommodate BPG
D. BPG binds to the R state with the same affinity as the T state
Answer:C
Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because
A. it is displaced from the heme by oxygen B. it is displaced from the heme by movement of the proximal histidine C. its binding pocket becomes too small to accommodate BPG D. BPG binds to the R state with the same affinity as the T state