Barrett’s esophagus is a complication of gastroesophageal reflux disease. Which of the following statement(s) is/are true concerning this condition?
A. The histologic hallmark is the presence of “specialized” columnar epithelium regardless of how far it extends into the esophagus
B. Barrett’s epithelium will frequently regress with medical therapy or anti-reflux surgery
C. High grade dysplasia will frequently be associated with foci of invasive carcinoma
D. Patients with adenocarcinoma arising in Barrett’s esophagus have a high incidence of p53 gene mutations
Answer:A
Barrett’s esophagus is a complication of gastroesophageal reflux disease. Which of the following statement(s) is/are true concerning this condition?
A. The histologic hallmark is the presence of “specialized” columnar epithelium regardless of how far it extends into the esophagus B. Barrett’s epithelium will frequently regress with medical therapy or anti-reflux surgery C. High grade dysplasia will frequently be associated with foci of invasive carcinoma D. Patients with adenocarcinoma arising in Barrett’s esophagus have a high incidence of p53 gene mutations