Familial hypercholesterolemia has been proposed as a disease to be treated by gene therapy. The molecular basis of familial hypercholesterolemia is which of the following?
A. Absence of hepatic low density lipoprotein receptors
B. Overproduction of high density lipoprotein
C. Absence of lipoprotein lipase
D. Overproduction of hepatic ornithine transcarbamylase
Answer:A
Familial hypercholesterolemia has been proposed as a disease to be treated by gene therapy. The molecular basis of familial hypercholesterolemia is which of the following?
A. Absence of hepatic low density lipoprotein receptors B. Overproduction of high density lipoprotein C. Absence of lipoprotein lipase D. Overproduction of hepatic ornithine transcarbamylase