Development of duodenal ulceration is dependent upon gastric acid secretion. Which of the following statements correctly characterizes acid secretion in duodenal ulcer patients?
A. Groups of duodenal ulcer patients demonstrate decreased basal acid secretion
B. Maximal acid output to histamine averages 40 mEq/h in duodenal ulcer patients, twice that of normal
C. Tissue gastrin levels, on average, are twice normal in patients with active ulceration
D. Exogenously administered somatostatin is ineffective in suppressing acid secretion in patients with active ulceration
Answer:B
Development of duodenal ulceration is dependent upon gastric acid secretion. Which of the following statements correctly characterizes acid secretion in duodenal ulcer patients?
A. Groups of duodenal ulcer patients demonstrate decreased basal acid secretion B. Maximal acid output to histamine averages 40 mEq/h in duodenal ulcer patients, twice that of normal C. Tissue gastrin levels, on average, are twice normal in patients with active ulceration D. Exogenously administered somatostatin is ineffective in suppressing acid secretion in patients with active ulceration