Which of the following is/are true about colorectal polyps?
A. Familial juvenile polyposis is associated with an increased incidence of colon cancer.
B. Although the propensity for development of malignancy is related to the size of a neoplastic polyp, those with mixed tubulovillous histologic appearance are most likely to develop malignant changes.
C. The loss of a single tumor suppressor gene such as p53 is sufficient to lead to the development of malignancy in colorectal neoplastic polyps.
D. Endoscopic polypectomy results in a decreased incidence of carcinomas of the colon and rectum.
Answer:A
Which of the following is/are true about colorectal polyps?
A. Familial juvenile polyposis is associated with an increased incidence of colon cancer. B. Although the propensity for development of malignancy is related to the size of a neoplastic polyp, those with mixed tubulovillous histologic appearance are most likely to develop malignant changes. C. The loss of a single tumor suppressor gene such as p53 is sufficient to lead to the development of malignancy in colorectal neoplastic polyps. D. Endoscopic polypectomy results in a decreased incidence of carcinomas of the colon and rectum.