In an effort to improve survival following esophageal resection, trials of multi-modality therapy in combination with surgery have been completed. Which of the following statement(s) is/are true concerning such treatment?
A. Therapy appears to be indicated in squamous cell carcinoma but not adenocarcinoma
B. No residual carcinoma may be found in the resected specimen in up to 20% of patients
C. Nonrandomized trials would suggest improved survival compared to patients receiving surgery alone
D. Perioperative morbidity is increased due to preoperative radiation and chemotherapy
Answer:B
In an effort to improve survival following esophageal resection, trials of multi-modality therapy in combination with surgery have been completed. Which of the following statement(s) is/are true concerning such treatment?
A. Therapy appears to be indicated in squamous cell carcinoma but not adenocarcinoma B. No residual carcinoma may be found in the resected specimen in up to 20% of patients C. Nonrandomized trials would suggest improved survival compared to patients receiving surgery alone D. Perioperative morbidity is increased due to preoperative radiation and chemotherapy