Current clinical protocols determine a limited number of variables and parameters for matching and allocation of donor organs to potential recipients. Which of the following statement(s) is/are true concerning aspects of immunity important for clinical transplantation?
A. HLA matching is important for kidney, pancreas, and liver transplantation
B. A cross match assay determines if there are preformed antibodies in the recipient’s serum which will react with antigens on the cell surface of the potential donor’s lymphocytes
C. A patient with a history of multiple transfusions or previous transplant will have a high panel reactive antibody (PRA)
D. A normal heterozygous individual with a complete donor-recipient match will have a four-antigen match
Answer:B
Current clinical protocols determine a limited number of variables and parameters for matching and allocation of donor organs to potential recipients. Which of the following statement(s) is/are true concerning aspects of immunity important for clinical transplantation?
A. HLA matching is important for kidney, pancreas, and liver transplantation B. A cross match assay determines if there are preformed antibodies in the recipient’s serum which will react with antigens on the cell surface of the potential donor’s lymphocytes C. A patient with a history of multiple transfusions or previous transplant will have a high panel reactive antibody (PRA) D. A normal heterozygous individual with a complete donor-recipient match will have a four-antigen match