Resistance of tumors to multiple chemotherapeutic agents is often due to the MDR (Multiple Drug Resistance) gene. This gene encodes a protein that acts by which of the following mechanisms?
A. As a transmembrane efflux pump for chemotherapeutic agents
B. As a DNA repair molecule
C. As an isoform of superoxide dismutase
D. As a membrane stabilizer
Answer:A
Resistance of tumors to multiple chemotherapeutic agents is often due to the MDR (Multiple Drug Resistance) gene. This gene encodes a protein that acts by which of the following mechanisms?
A. As a transmembrane efflux pump for chemotherapeutic agents B. As a DNA repair molecule C. As an isoform of superoxide dismutase D. As a membrane stabilizer