Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of the following statement(s) is/are true concerning intracellular receptors?
A. The messengers or hormones must by lipophilic
B. These intracellular receptors generally regulate protein synthesis
C. The intracellular receptors are located entirely in the nucleus of the cell
D. A heat-shock protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor
Answer:A
Most hormone receptors are localized on the cell membrane and transduce hormone binding into altered levels of intracellular messengers. A limited number of intracellular receptors do exist. Which of the following statement(s) is/are true concerning intracellular receptors?
A. The messengers or hormones must by lipophilic B. These intracellular receptors generally regulate protein synthesis C. The intracellular receptors are located entirely in the nucleus of the cell D. A heat-shock protein serves as an inhibitor protein blocking the DNA-binding domain of the steroid receptor