Historically, the small intestine was presumed to have only digestive and absorptive function. However, in the last decade the small intestine has become recognized as the body’s largest endocrine organ, producing a number of hormones, neurotransmitters, and paracrine substances. Which of the following statement(s) is/are true concerning small bowel hormones?
A.	Cholecystokinin (CCK) is produced from cells in the mucosa of the duodenum and jejunum and is released in response to luminal fats and proteins
B.	Secretin is released in response to rising intraduodenal pH, resulting in inhibition of pancreatic secretion
C.	Motilin is a 22-amino acid peptide released during the fasting state with increased levels corresponding with the onset of the migrating motor complex (MMC)
D.	Neurotensin is produced primarily in the duodenal mucosa and its release is stimulated primarily by carbohydrates and proteins
Answer:A
Historically, the small intestine was presumed to have only digestive and absorptive function. However, in the last decade the small intestine has become recognized as the body’s largest endocrine organ, producing a number of hormones, neurotransmitters, and paracrine substances. Which of the following statement(s) is/are true concerning small bowel hormones?
A.	Cholecystokinin (CCK) is produced from cells in the mucosa of the duodenum and jejunum and is released in response to luminal fats and proteins B.	Secretin is released in response to rising intraduodenal pH, resulting in inhibition of pancreatic secretion C.	Motilin is a 22-amino acid peptide released during the fasting state with increased levels corresponding with the onset of the migrating motor complex (MMC) D.	Neurotensin is produced primarily in the duodenal mucosa and its release is stimulated primarily by carbohydrates and proteins