A 45-year-old man with long-standing gastroesophageal reflux undergoes upper endoscopy that reveals patchy areas of epithelium resembling gastric mucosa extending 5 cm proximal to the esophagogastric junction. Biopsies are obtained. The pathologic report describes “Barrett’s epithelium”. Which of the following processes does this finding represent?
A. Cellular hyperplasia
B. Cellular hypertrophy
C. Metaplasia
D. Carcinoma in situ
Answer:C
A 45-year-old man with long-standing gastroesophageal reflux undergoes upper endoscopy that reveals patchy areas of epithelium resembling gastric mucosa extending 5 cm proximal to the esophagogastric junction. Biopsies are obtained. The pathologic report describes “Barrett’s epithelium”. Which of the following processes does this finding represent?
A. Cellular hyperplasia B. Cellular hypertrophy C. Metaplasia D. Carcinoma in situ