A 45 year-old woman presents for evaluation of hypertension, recent onset obesity, hirsutism and depression. Cerebral MRI does not show a pituitary lesion. Evaluation may include determination of which of the following?
A. AM serum cortisol levels after low dose dexamethasone suppression
B. Simultaneous serum ACTH measurement in peripheral and inferior petrosal sinus sites
C. Chest and abdominal CT scan
D. Urinary free cortisol excretion
Answer:B
A 45 year-old woman presents for evaluation of hypertension, recent onset obesity, hirsutism and depression. Cerebral MRI does not show a pituitary lesion. Evaluation may include determination of which of the following?
A. AM serum cortisol levels after low dose dexamethasone suppression B. Simultaneous serum ACTH measurement in peripheral and inferior petrosal sinus sites C. Chest and abdominal CT scan D. Urinary free cortisol excretion