) Administration by oral gavage of a test compound that is highly metabolized by the liver versus subcutaneous injection will most likely result in
A.) less parent compound present in the systemic circulation
B.) lower levels of metabolites in the systemic circulation
C.) more systemic toxicity
D.) less systemic toxicity
Answer:A
) Administration by oral gavage of a test compound that is highly metabolized by the liver versus subcutaneous injection will most likely result in
A.) less parent compound present in the systemic circulation B.) lower levels of metabolites in the systemic circulation C.) more systemic toxicity D.) less systemic toxicity