Bob is allergic to ragweed pollen. He has been treated with ragweed pollen allergen using a minute concentration and gradually increasing doses repeatedly for desensitization (hyposensitization) therapy to reduce the allergic reaction. Hyposensitization probably operates using which of the following principles?
A. clearance of antigen-specific IgE immune complexes
B. greater production of circulating high affinity IgG antibody
C. depletion of the mast cell pool by repeated degranulation
D. specific tolerance induction
Answer:B
Bob is allergic to ragweed pollen. He has been treated with ragweed pollen allergen using a minute concentration and gradually increasing doses repeatedly for desensitization (hyposensitization) therapy to reduce the allergic reaction. Hyposensitization probably operates using which of the following principles?
A. clearance of antigen-specific IgE immune complexes B. greater production of circulating high affinity IgG antibody C. depletion of the mast cell pool by repeated degranulation D. specific tolerance induction