Which of the following represent obstacles to the use of retroviruses in therapeutic gene transfer?
A. Viral receptors may not be present on target cell membranes
B. For integration, the host cell must undergo mitosis
C. Virus particles are labile
D. Viral purification is difficult
Answer:A
Which of the following represent obstacles to the use of retroviruses in therapeutic gene transfer?
A. Viral receptors may not be present on target cell membranes B. For integration, the host cell must undergo mitosis C. Virus particles are labile D. Viral purification is difficult