Cystic fibrosis is a genetic disease that results from a defective CFTR protein that alters ion flow through the cell membrane such that water does not cross the cell membrane. Gene therapy is being used to attempt to help cystic fibrosis patients. Which of the following steps is not needed to develop a gene therapy treatment for cystic fibrosis?
A. Clone the normal-functioning CFTR gene and make an RNA version of the gene.
B. Make antibodies to the defective CFTR protein to enhance the patient’s immune system.
C. Remove cells from a patient and infect them with the recombinant virus.
D. Insert the RNA version of the CFTR gene into a virus.
Answer:B
Cystic fibrosis is a genetic disease that results from a defective CFTR protein that alters ion flow through the cell membrane such that water does not cross the cell membrane. Gene therapy is being used to attempt to help cystic fibrosis patients. Which of the following steps is not needed to develop a gene therapy treatment for cystic fibrosis?
A. Clone the normal-functioning CFTR gene and make an RNA version of the gene. B. Make antibodies to the defective CFTR protein to enhance the patient’s immune system. C. Remove cells from a patient and infect them with the recombinant virus. D. Insert the RNA version of the CFTR gene into a virus.