Which of the following statements is most accurate regarding infection with parvovirus B19?
A. Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors
B. Parvovirus B19 can cause hydrops fetalis via transplacental infection of a fetus in a seropositive mother
C. Parvovirus B19 can be diagnosed by detection of viral RNA using PCR or hybridization assays
D. Parvovirus B19 replicates in the host cell nucleus utilizing a virally encoded DNA polymerase to create a double- stranded DNA intermediate
Answer:A
Which of the following statements is most accurate regarding infection with parvovirus B19?
A. Parvovirus B19 causes severe anemia because it preferentially infects erythrocyte precursors B. Parvovirus B19 can cause hydrops fetalis via transplacental infection of a fetus in a seropositive mother C. Parvovirus B19 can be diagnosed by detection of viral RNA using PCR or hybridization assays D. Parvovirus B19 replicates in the host cell nucleus utilizing a virally encoded DNA polymerase to create a double- stranded DNA intermediate