<p><b>丙二酸二甲酯</b>（<b>Dimethyl malonate</b>）是由丙二酸與甲醇的酯化反應得到的二酯，在有機合成上作為巴比妥酸的前體。
</p>
<h2><span id=".E5.90.88.E6.88.90"></span><span id="合成">合成</span></h2>
<p>丙二酸二甲酯可由甲縮醛與CO反應製得：</p>
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<ul><li>丙二酸二乙酯</li></ul><h2><span id=".E5.8F.82.E8.80.83.E8.B5.84.E6.96.99"></span><span id="参考资料">參考資料</span></h2>
**丙二酸二甲酯**（**Dimethyl malonate**）是由丙二酸與甲醇的酯化反應得到的二酯，在有機合成上作為巴比妥酸的前體。

## 合成

丙二酸二甲酯可由甲縮醛與 CO 反應製得：

　
: $\mathrm {H_{2}C(OCH_{3})_{2}+2\ CO\longrightarrow CH_{2}(CO_{2}CH_{3})_{2}} $

## 參見

* 丙二酸二乙酯

## 參考資料
108-59-8