<p><b>黃酮醇合酶</b>（英語：<span lang="en">flavonol synthase</span>；EC 1.14.11.23）在酶學中在酶學中是一個催化如下化學反應的酶。
</p>
<dl><dd>黃烷酮醇 + α-酮戊二酸 + O<sub>2</sub> <span><span><math xmlns="http://www.w3.org/1998/Math/MathML" alttext="{\displaystyle \rightleftharpoons }">
  <semantics>
    <mrow class="MJX-TeXAtom-ORD">
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        <mo class="MJX-variant" stretchy="false">⇌<!-- ⇌ --></mo>
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    <annotation encoding="application/x-tex">{\displaystyle \rightleftharpoons }</annotation>
  </semantics></math></span></span> 黃酮醇 + 琥珀酸 + CO<sub>2</sub> + H<sub>2</sub>O</dd></dl><p>此酶的三種底物分別是黃烷酮醇、α-酮戊二酸與氧氣，而它的四種產物則分別是黃酮醇、琥珀酸、二氧化碳與水。
</p><p>此酶屬於氧化還原酶家族，特異性地作用於配對的供體，並以氧氣作為氧化劑結合或還原氧氣。被結合的氧無需藉由α-酮戊二酸作為一個供體或是被脫氫的方式被傳遞。此酶類的系統命名為<b>黃烷酮醇，2-酮戊二酸：氧氧化還原酶</b>。此酶參與黃酮類化合物生物合成。
</p>
<h2><span id=".E5.8F.82.E8.80.83.E6.96.87.E7.8C.AE"></span><span id="参考文献">參考文獻</span></h2>

<ul><li><cite class="citation journal">Wellmann F, Lukacin R, Moriguchi T, Britsch L, Schiltz E, Matern U. Functional expression and mutational analysis of flavonol synthase from Citrus unshiu. Eur. J. Biochem. 2002, <b>269</b> (16): 4134–42. <span title="公共醫學識別碼">PMID 12180990</span>. <span title="數位物件識別號">doi:10.1046/j.1432-1033.2002.03108.x</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%BB%84%E9%85%AE%E9%86%87%E5%90%88%E9%85%B6&amp;rft.atitle=Functional+expression+and+mutational+analysis+of+flavonol+synthase+from+Citrus+unshiu&amp;rft.au=Wellmann+F%2C+Lukacin+R%2C+Moriguchi+T%2C+Britsch+L%2C+Schiltz+E%2C+Matern+U&amp;rft.date=2002&amp;rft.genre=article&amp;rft.issue=16&amp;rft.jtitle=Eur.+J.+Biochem.&amp;rft.pages=4134-42&amp;rft.volume=269&amp;rft_id=info%3Adoi%2F10.1046%2Fj.1432-1033.2002.03108.x&amp;rft_id=info%3Apmid%2F12180990&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal"><span> </span></span></li>
<li><cite class="citation journal">Lukacin R, Wellmann F, Britsch L, Martens S, Matern U. Flavonol synthase from Citrus unshiu is a bifunctional dioxygenase. Phytochemistry. 2003, <b>62</b> (3): 287–92. <span title="公共醫學識別碼">PMID 12620339</span>. <span title="數位物件識別號">doi:10.1016/S0031-9422(02)00567-8</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%BB%84%E9%85%AE%E9%86%87%E5%90%88%E9%85%B6&amp;rft.atitle=Flavonol+synthase+from+Citrus+unshiu+is+a+bifunctional+dioxygenase&amp;rft.au=Lukacin+R%2C+Wellmann+F%2C+Britsch+L%2C+Martens+S%2C+Matern+U&amp;rft.date=2003&amp;rft.genre=article&amp;rft.issue=3&amp;rft.jtitle=Phytochemistry.&amp;rft.pages=287-92&amp;rft.volume=62&amp;rft_id=https%3A%2F%2Farchive.org%2Fdetails%2Fsim_phytochemistry_2003-02_62_3%2Fpage%2F287&amp;rft_id=info%3Adoi%2F10.1016%2FS0031-9422%2802%2900567-8&amp;rft_id=info%3Apmid%2F12620339&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal"><span> </span></span></li>
<li><cite class="citation journal">Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R. Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley. FEBS. Lett. 2003, <b>544</b> (1-3): 93–8. <span title="公共醫學識別碼">PMID 12782296</span>. <span title="數位物件識別號">doi:10.1016/S0014-5793(03)00479-4</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%BB%84%E9%85%AE%E9%86%87%E5%90%88%E9%85%B6&amp;rft.atitle=Divergent+evolution+of+flavonoid+2-oxoglutarate-dependent+dioxygenases+in+parsley&amp;rft.au=Martens+S%2C+Forkmann+G%2C+Britsch+L%2C+Wellmann+F%2C+Matern+U%2C+Lukacin+R&amp;rft.date=2003&amp;rft.genre=article&amp;rft.issue=1-3&amp;rft.jtitle=FEBS.+Lett.&amp;rft.pages=93-8&amp;rft.volume=544&amp;rft_id=info%3Adoi%2F10.1016%2FS0014-5793%2803%2900479-4&amp;rft_id=info%3Apmid%2F12782296&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal"><span> </span></span></li>
<li><cite class="citation journal">CJ; Nakajima, J; Welford, RW; Yamazaki, M; Saito, K; Schofield, CJ. Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase. J. Biol. Chem. 2004, <b>279</b> (2): 1206–16. <span title="公共醫學識別碼">PMID 14570878</span>. <span title="數位物件識別號">doi:10.1074/jbc.M309228200</span>.</cite><span title="ctx_ver=Z39.88-2004&amp;rfr_id=info%3Asid%2Fzh.wikipedia.org%3A%E9%BB%84%E9%85%AE%E9%86%87%E5%90%88%E9%85%B6&amp;rft.atitle=Mechanistic+studies+on+three+2-oxoglutarate-dependent+oxygenases+of+flavonoid+biosynthesis%3A+anthocyanidin+synthase%2C+flavonol+synthase%2C+and+flavanone+3beta-hydroxylase&amp;rft.au=CJ&amp;rft.au=Nakajima%2C+J&amp;rft.au=Saito%2C+K&amp;rft.au=Schofield%2C+CJ&amp;rft.au=Welford%2C+RW&amp;rft.au=Yamazaki%2C+M&amp;rft.date=2004&amp;rft.genre=article&amp;rft.issue=2&amp;rft.jtitle=J.+Biol.+Chem.&amp;rft.pages=1206-16&amp;rft.volume=279&amp;rft_id=info%3Adoi%2F10.1074%2Fjbc.M309228200&amp;rft_id=info%3Apmid%2F14570878&amp;rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal"><span> </span></span></li></ul><!-- 
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**黃酮醇合酶**（英語：flavonol synthase；EC 1.14.11.23）在酶學中在酶學中是一個催化如下化學反應的酶。

　
: 黃烷酮醇 + α- 酮戊二酸 + O2 $\rightleftharpoons $ 黃酮醇 + 琥珀酸 + CO2 + H2O

此酶的三種底物分別是黃烷酮醇、α- 酮戊二酸與氧氣，而它的四種產物則分別是黃酮醇、琥珀酸、二氧化碳與水。

此酶屬於氧化還原酶家族，特異性地作用於配對的供體，並以氧氣作為氧化劑結合或還原氧氣。被結合的氧無需藉由 α- 酮戊二酸作為一個供體或是被脫氫的方式被傳遞。此酶類的系統命名為**黃烷酮醇，2 - 酮戊二酸：氧氧化還原酶**。此酶參與黃酮類化合物生物合成。

## 參考文獻

* Wellmann F, Lukacin R, Moriguchi T, Britsch L, Schiltz E, Matern U. Functional expression and mutational analysis of flavonol synthase from Citrus unshiu. Eur. J. Biochem. 2002, **269** (16): 4134–42. PMID 12180990. doi:10.1046/j.1432-1033.2002.03108.x.
* Lukacin R, Wellmann F, Britsch L, Martens S, Matern U. Flavonol synthase from Citrus unshiu is a bifunctional dioxygenase. Phytochemistry. 2003, **62** (3): 287–92. PMID 12620339. doi:10.1016/S0031-9422(02)00567-8.
* Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R. Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley. FEBS. Lett. 2003, **544** (1-3): 93–8. PMID 12782296. doi:10.1016/S0014-5793(03)00479-4.
* CJ; Nakajima, J; Welford, RW; Yamazaki, M; Saito, K; Schofield, CJ. Mechanistic studies on three 2-oxoglutarate-dependent oxygenases of flavonoid biosynthesis: anthocyanidin synthase, flavonol synthase, and flavanone 3beta-hydroxylase. J. Biol. Chem. 2004, **279** (2): 1206–16. PMID 14570878. doi:10.1074/jbc.M309228200.
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