Title: PALM: Preference-based Adversarial Manipulation against Deep Reinforcement Learning. Abstract: To improve the robustness of DRL agents, it is important to study their vulnerability under  adversarial attacks that would lead to extreme behaviors desired by adversaries. Preference-based RL (PbRL) aims for learning desired behaviors with human preferences. In this paper, we propose PALM, a preference-based adversarial manipulation method against DRL agents  which adopts human preferences to perform targeted attacks with the assistance of an intention policy and a weighting function. The intention policy is trained based on the PbRL framework to guide the adversarial policy  to mitigate restrictions of the victim policy during exploration, and the weighting function learns weight assignment to improve the performance of the adversarial policy. Theoretical analysis demonstrates that PALM converges to critical points under some mild conditions. Empirical results on a few manipulation tasks of Meta-world show that PALM exceeds the performance of state-of-the-art adversarial attack methods under the targeted setting. Additionally, we show the vulnerability of the offline RL agents by fooling them into behaving as human desires on several Mujoco tasks. Our code and videos are available in https://sites.google.com/view/palm-adversarial-attack.