Title: Towards Boosting the Open-Domain Chatbot with Human Feedback. Abstract: Many open-domain dialogue models pre-trained with social media comments can generate coherent replies but have difficulties producing engaging responses. This phenomenon might mainly result from the deficiency of annotated human-human conversations and the misalignment with human preference. In this paper, we propose a novel and efficient framework Diamante to boost the open-domain chatbot, where two kinds of human feedback (including explicit demonstration and implicit preference) are collected and leveraged. By asking annotators to select or amend the model-generated candidate responses, Diamante efficiently collects the human demonstrated responses and constructs a Chinese chit-chat dataset. To enhance the alignment with human preference, Diamante leverages the implicit preference in the data collection process and introduces the generation-evaluation joint training. Comprehensive experiments indicate that the Diamante dataset and joint training paradigm can significantly boost the performance of pre-trained dialogue models. The overall engagingness of the previous state-of-the-art model has been improved remarkably by 50% in Chinese open-domain conversations.