Datasets:
miraesunnykim
commited on
Commit
·
6c5b82b
1
Parent(s):
30f3b58
remove basenames, add readme
Browse files- README.md +33 -0
- label_transfer_meta.parquet +0 -0
- training_meta.parquet +0 -0
README.md
ADDED
|
@@ -0,0 +1,33 @@
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| 1 |
+
|
| 2 |
+
# Methylation-classification Dataset
|
| 3 |
+
|
| 4 |
+
## Dataset Description
|
| 5 |
+
|
| 6 |
+
- **Homepage:** https://github.com/ylaboratory/methylation-classification
|
| 7 |
+
- **Pubmed:** False
|
| 8 |
+
- **Public:** True
|
| 9 |
+
|
| 10 |
+
Methylation classification is a pan-tissue dataset and analysis paper from publicaly available DNA methylation microarrays (450K) from the Gene Expression Omnibus. The uploaded dataset of 16,959 samples encompasss 86 tissue and cell types.
|
| 11 |
+
|
| 12 |
+
## Data and usage
|
| 13 |
+
|
| 14 |
+
Analysis code, annotation, data files, and skeleton preprocessing code (if running starting from raw files) are located in this repo and [github](https://github.com/ylaboratory/methylation-classification).
|
| 15 |
+
|
| 16 |
+
mvalues files contain methylation M-values preprocessed and quality controlled using minfi and wateRmelon:
|
| 17 |
+
- background corrected using [preprocessNoob](https://rdrr.io/bioc/minfi/man/preprocessNoob.html)
|
| 18 |
+
- normalized using [BMIQ](https://rdrr.io/bioc/wateRmelon/man/BMIQ.html)
|
| 19 |
+
|
| 20 |
+
meta files contain the following:
|
| 21 |
+
- Sample ID
|
| 22 |
+
- training.ID: UBERON ID used for training (physiologically similar IDs merged, few tissues labeled as system-level node to aid in training)
|
| 23 |
+
- Dataset: GSE study ID
|
| 24 |
+
- Annotated.tissue: initially annotated tissue
|
| 25 |
+
- UBERON.ID: annotated tissue's most descriptive UBERON ID
|
| 26 |
+
- merged.ID: UBERON IDs after merging physiologically similar IDs
|
| 27 |
+
|
| 28 |
+
## Citation Information
|
| 29 |
+
|
| 30 |
+
```
|
| 31 |
+
coming soon
|
| 32 |
+
```
|
| 33 |
+
|
label_transfer_meta.parquet
CHANGED
|
Binary files a/label_transfer_meta.parquet and b/label_transfer_meta.parquet differ
|
|
|
training_meta.parquet
CHANGED
|
Binary files a/training_meta.parquet and b/training_meta.parquet differ
|
|
|