You can use Photoshop to edit individual frames of video and image sequence files. In addition to using any Photoshop tool to edit and paint on video, you can also apply filters, masks, transformations, layers styles, and blending modes. After making edits, you can save the document as a PSD file (that can be played back in other Adobe applications such as Premiere Pro and After Effects or accessed as a static file in other applications), or you can render it as a QuickTime movie or image sequence.