The vitality of medical papers is that it is scientific. The so-called "science", and in the authenticity, completeness and logical three aspects. Requested from the topic, design, observational study to the reasoning and conclusions of each step there is a serious attitude, strict requirements and rigorous methods, topics have enough scientific evidence, the design should have sufficient reliability, comparability and the necessary randomness, observational study to be true, accurate and comprehensive, with emphasis on logical reasoning and conclusions of rigor. no scientific "paper" is not only worthless, but also can someone astray, causing harmful effects.