On the other hand, a large U.S. multicenter study (2) shows that older men with higher testosterone levels are more likely to have a heart attack or other cardiovascular disease in the future. Researchers led by Kristen Sueoka studied 697 community-dwelling men age 65 or older who were participating in the National Institutes of Health-funded study, Osteoporotic Fractures in Men (MrOS). None of these men were receiving testosterone therapy, according to the study abstract.