Niche-based theories, the author established the headquarters of the central city's economic development strategic positioning framework. According to niche-state, ecological potential, niche breadth, niche overlap analysis of four companies in which the urban ecological environment, so as to formulate appropriate niche based economic development strategy, The framework, respectively, from niche breadth, niche overlap of two pairs of resource utilization as well as the city and surrounding cities to analyze the degree of overlap of resources, ecology and ecological niche potential of existing resources, respectively, from the city's potential and resources to further enrich for analysis. internal environment, the framework of regional cooperation from the city point of view, the headquarters of the regional economic development strategy to achieve staggered development, to achieve the optimal allocation of urban resources.