In addition, it must be the first time that you have manufactured or imported the substance in quantities greater than one tonne per year or more after December 1, 2008. If both of these conditions are met, late pre-registration has to be submitted within six months of first manufacturing, importing or using the substance and no later than 12 months before the relevant tonnage band deadline. Other chemical substances, that do not meet the above conditions, must be submitted for registration straight after submitting an inquiry dossier to the European Chemicals Agency (ECHA).