Phase: Architecture and Design
For any security checks that are performed on the client side, ensure that these checks are duplicated on the server side, in order to avoid CWE-602. Attackers can bypass the client-side checks by modifying values after the checks have been performed, or by changing the client to remove the client-side checks entirely. Then, these modified values would be submitted to the server.
Phase: Implementation
Do not rely exclusively on sanity checks of file contents to ensure that the file is of the expected type and size. It may be possible for an attacker to hide code in some file segments that will still be executed by the server. For example, GIF images may contain a free-form comments field.