Metformin is generally recommended as a first-line treatment for type 2 diabetes, as there is good evidence that it decreases mortality.[8] It works by decreasing the liver's production of glucose.[116] Several other groups of drugs, mostly given by mouth, may also decrease blood sugar in type 2 diabetes.
Metformin biasonyo direkomendasikan pado lini partamo ubek untuak diabetes tipe 2, alah ado pulo bukti baso dapek manurunkan risiko kamatian.[65] Ubek ko bakarajo jo manurunkan produksi glukosa hepar (hati).[66] Babarapo kalompok ubek lain, umumnyo lewaik muluik, dapek menurunkan kadar gulo darah pado DM tipe 2.