The process is much the same as that in knockout engineering, except that the construct is designed to increase the function of the gene, usually by providing extra copies of the gene or inducing synthesis of the protein more frequently.
Pidabdab nyane pateh sareng pidabdab knockout, sajebag ning pidabdab sane wau kecancerang anggen nincapang kawigunan gen, inggian ngicen penyalin pawewehan gen utawi  ngamargiang induksi sintesis protein sane sayan sering kamargiang.