Yadiastun ngeragi puniki nenten akeh karesepang kantos karya Louis Pasteur  ring warsa 1857, puniki kantun kapertama ngawigunayang bioteknologi anggen nguwah sumber ajeng-ajengan dados  soroh sane tiosan.
Although the process of fermentation was not fully understood until Louis Pasteur's work in 1857, it is still the first use of biotechnology to convert a food source into another form.