Purdue Pharma
In 1996, Purdue Pharma started selling OxyContin, a new version of oxycodone, an opioid.  It was approved by the FDA in 1995 after no long-term studies and no assessment of how addictive it was. Their advertising to doctors was very effective. The drug was very successful and made  US$35 billion for Purdue.  It is very easy to be addicted to it.  From 1999 to 2020 opioids killed about 500,000 people in the USA.