Hittites
When Tutankhamun, the Egyptian Pharaoh died,his widow asked to marry one of Suppiluliuma's sons.  He agreed, and sent his son Zannanza to Egypt to marry the queen.  However, Zannanza was assassinated en route to Egypt. Suppiluliuma was furious and blamed the new Egyptian Pharaoh Ay for his son's death. A Hittite army under crown prince Arnuwanda invaded Egyptian territory from Syria, pillaging and taking many prisoners. These prisoners brought with them a plague which ravaged the Hittite Kingdom continuing well into Mursili's reign and may have killed Suppiluliuma himself.