Helios Airways
On 14 August 2005, Helios Airways Flight 522, a Boeing 737-300 flying from Larnaca to Prague via Athens crashed near Grammatiko, Greece. The flight crew had become incapacitated shortly after take-off from Larnaca owing to a loss of cabin pressure. The autopilot entered a holding pattern over Athens and the aircraft began to descend after the fuel was exhausted, crashing into hilly terrain about 40 km north of Athens International Airport. All 121 passengers and crew were killed in the accident.