A Brief History of Time
The uncertainty principle says that the speed and the position of a particle cannot be found at the same time. To find where a particle is, scientists shine light at the particle. If a high frequency light is used, the light can find the position more accurately but the particle's speed will be unknown (because the light will change the speed of the particle). If a lower frequency light is used, the light can find the speed more accurately but the particle's position will be unknown. The uncertainty principle disproved the idea of a theory that was deterministic, or something that would predict everything in the future.