Creutzfeldt–Jakob disease
Most people with CJD die within six months after their first symptoms appeared.  Often, they die of pneumonia caused by trouble coughing. This is called aspiration pneumonia.  About 15% of patients survive for two or more years.  Some patients have lived 4–5 years with mostly mental symptoms until the disease gets worse and causes more physical symptoms.  Once this happens, people usually die within a year.