Polygenic score
Polygenic scores are made by finding lots of people who have a disease, and lots of people who do not. The DNA of these people is studied. Scientists see if DNA variations happen more in the people with the disease, or happen less in the people with the disease. This figures out which DNA variations, or genes, are important. Because some of these DNA variations are more important than others, the more important DNA variations affect the polygenic score more. Often, very big groups of people are used to make polygenic scores. One of these big groups of people is the UK Biobank.