Holby City
The first series had eleven main characters. All have since left the show. New main characters have been written in and out of the series. There are fifteen main characters. Well known actors regularly appear. Cast members have included Patsy Kensit, Jane Asher, Robert Powell, Ade Edmondson, John Michie, Al Hunter Ashton, Alex Walkinshaw and Jemma Redgrave.