Lysergic acid diethylamide
One day in 1943, Hofmann accidentally ate a small amount of LSD, and noticed strange light patterns in the sky as he went home. He believed that what he had experienced were the effects of the drug. He tried a larger amount next. He ended up with a much stronger reaction to the drug than he expected. Hofmann lay on a couch, afraid he had made himself insane for life. When a neighbor came, found him in trouble, and stayed to look after Hofmann, he was able to calm down, and even said he began to enjoy the plays of colorful shapes and patterns that occurred behind his closed eyes. The next day Hofmann reported to have waken up refreshed and clear-headed, though somewhat physically tired. He also noted that his breakfast tasted unusually delicious that morning.