Migraine
Estrogen is a hormone that is mostly made in a woman's ovaries. There are three types of estrogen: estrone, estradiol and estriol. In women who have migraines it is usually connected with their menstruation cycle. About 60% of women have these menstrual or menstrually-related migraines and the main trigger is believed to be reduced circulating estrogen levels, i.e. the amount of estrogen in the body, specifically estradiol. In some cases, fluctuation (going up and down) in the amount of circulating estrogen levels may trigger a migraine, i.e. not only too little but sometimes too much estrogen may trigger a migraine.