Santa Fe de Antioquia
Its cathedral was constructed in 1799 and elevated to Diocese of Antioquia in 1804 by Pope Pius VII. In 1813 Antioquia was declared a sovereign and independent state with Santa Fe as its capital, a status it maintained until 1826, when Medellín was chosen as the new departmental seat. Due to the state of conservation of its colonial architecture, it was declared a national monument in 1960.