Antiviral drug
Chronic hepatitis B: IFNα2Α 2.5−5 ΜU/m2 or IFNα2Β 5−10 ΜU given 3 times per week for 4–6 months causes disappearance of HBVDNA from plasma and improvement in liver function tests/histology in nearly half of the patients. High doses (10 MU) injected thrice weekly for 6 months often produce prolonged remission, but relapses do occur. The pegIFNs 180 μg s.c. weekly for 24 to 48 weeks produce better and more sustained responses.