Ambroise Paré
In 1536, Paré was a young war surgeon just getting started on the battlefield. He ran out of oil to seal soldiers' wounds after amputations. He made up a mix of egg yolks, oil of roses and turpentine. He applied this to several soldier's wounds. The next morning he was surprised to see those soldiers with the mix he made up were much better than the soldiers who had been scalded. He used ligatures to tie off arteries during amputations to stop bleeding.