Naruto (manga)
Tsunade, the Fifth Hokage, is the Hokage for most of the series. She was a student of the Third Hokage. She was a member of the Senju clan. Her grandfather Hashirama had superhuman strength. Tsunade uses a transformation technique to look young. At first, Tsunade did not want to be Hokage because her younger brother Nawaki and her boyfriend Dan Kato both died trying to be Hokage. Tsunade regained her faith after meeting Naruto Uzumaki. She became Hokage and taught Sakura and Ino. By the end of the series, Tsunade retired. She bestowed the Hokage title to Kakashi.