The Mask: The Animated Series
A third villain who made it to the TV series for a few times was the mad Dr. Amelia Chronos, who, with her ambitions of gaining power and dominance through the manipulation of time, often caused quite a lot of chaos through inventions like a machine that kept looping time every half hour for everyone but herself (so that even the Mask could never foil her plans, since by the time he got to her, everything would be reset to a half hour prior), a gun that reversed/fast forwarded time for whoever it was aimed at (so that the person would keep getting younger and younger until he/she became nothing, or became older and older until he/she was dead), a large time portal through which she could summon anything to defeat the Mask (such as prehistoric creatures, robots from the future, etc.) though none of them worked and an actual time machine through which she could travel into the past or future to manipulate events so that she would ultimately be victorious in her quest for world dominance.