Doctor Who
When the series returned in 2005, the Time Lords had disappeared in the "Time War". This was a very big war with the Daleks. The Doctor explained that he stopped the war by destroying Gallifrey, killing all of the Time Lords and Daleks. He believed he was the last of the Time Lords, until he discovered that the Master had also survived. Jenny, who was created artificially in The Doctor's Daughter, is not a true Time Lord. For many years, the Doctor felt sorry for destroying Gallifrey. In the 2013 episode The Day of the Doctor, the Doctor learns that he did not actually destroy his planet, but that he had moved it to another universe.