Black Death
Until the 1700s, the plague seems to have reappeared in Europe at least once every generation. Some of the smaller plagues were more intense than others and caused more deaths. Later outbreaks include the Italian Plague of 1629–1631, the Great Plague of London (1665–1666), the Great Plague of Vienna (1679), the Great Plague of Marseille in 1720–1722, and the 1771 plague in Moscow. The most virulent form of the plague seems to have disappeared from Europe in the 18th century.