Hannibal Lecter
Lecter returned in The Silence of the Lambs, the sequel to Red Dragon. The movie based on this book became very popular. The book is about an FBI agent named Clarice Starling (played by Jodie Foster in the movie), who, like Will Graham from Red Dragon, is trying to catch a serial killer, who calls himself "Buffalo Bill" because he skins his victims like buffalo. Starling makes a deal with Lecter in which she will try to get him transferred to another prison (Lecter hates his cell) if he will help her understand Buffalo Bill's mind. In the end, Starling catches Bill, but Lecter escapes from prison, fleeing to Africa.