Pharmacology
The American market was worth more than $600 billion in 2022, almost half the global total.  Americans pay three times as much for branded drugs as the OECD average.  American research and development spending was nearly two-thirds of the OECD total. The 2022 Inflation Reduction Act lets Medicare bargain directly with drugmakers. It plans to seek cuts of 25% in some drugs.  Private health insurers  may do the same.