Lucy Webb Hayes
In the Lucky Luke comic book Sarah Bernhardt, which is set in the late 19th-century Wild West, President Rutherford B. Hayes's wife is portrayed as being one of many who strongly disapproves of the titular actress's tour of the United States, given her reputation for loose morality. Disguised as a man called “George,” the First Lady infiltrates Sarah’s entourage and sabotages their tour throughout the U.S., though she does come to accept Sarah when the French actress's charms and singing talent moves a tribe of hostile Indians.  "The president’s wife" is not mentioned by name in the book, and thus might be regarded as fictional, although she and her husband do resemble Rutherford and Lucy Hayes in many ways. Hayes himself is portrayed as a man who is very taken aback by his wife's hostility towards Sarah, and keeps making the same speech over and over again, even when there is no one there to listen to him.