Müllerian agenesis
Müllerian agenesis is a rare birth defect. It is also called Mayer-Rokitansky-Kuster-Hauser syndrome or MRKH. People with the syndrome are born without vaginas, cervixes, and wombs. MRKH is a rare genetic disorder that affects a woman's reproductive system. It is characterized by the absence of the uterus and the upper part of the vagina. It occurs in about 1 in 4,500 to 5,000 female births. Women with MRKH syndrome have normal external genitalia and normal secondary sexual characteristics, but they are unable to remain pregnant because they do not have an uterus. The cause of MRKH syndrome is unknown.  It probably is a genetic disorder that occurs during fetal development. There is no cure for MRKH syndrome, but treatment options, such as hormone therapy and surgery, can help women manage the condition and lead healthy, fulfilling lives.