Oncogene
The MYC gene is implicated in Burkitt's Lymphoma. This starts when a chromosomal translocation moves an enhancer sequence close to the MYC gene. The MYC gene codes for widely used transcription factors. When the enhancer sequence is wrongly placed, these transcription factors are produced at much higher rates. Another example of an oncogene is the Bcr-Abl gene found on the 'Philadelphia Chromosome'. This is a piece of genetic material seen in Chronic Myelogenous Leukemia, caused by the translocation of pieces from chromosomes 9 and 22. Bcr-Abl codes for a receptor tyrosine kinase, which is active, causing uncontrolled cell proliferation.