Orion (constellation)
The ancient Egyptians equated the constellation with Osiris, god of the afterlife.  The ancient Egyptian "First Time", "when Osiris walked on the Earth", has by some fringe archeologists been held to be around 10,500 BC; thanks to precession (which was known to the astronomers of the Early Dynasties), around that time at the Spring Equinox the constellation could be seen "walking" on the horizon just before dawn.