Horseshoe crab
Horseshoe crabs may be threatened by Asian overconsumption and by their use by pharmaceutical companies.  The tri-spine horseshoe crab, was listed as endangered by the International Union for Conservation of Nature in 2019.  In 2023 BNP Paribas wrote to 14 of the world’s largest pharmaceutical companies asking them to use a cloned substance called recombinant factor C instead of blood from horseshoe crabs for tests.  The Pharmaceutical Supply Chain Initiative, a lobby group set up by large pharmaceutical companies  said its members should stop sourcing blood from the two Asian horseshoe crab species most at risk.