Cocaine
In America, cocaine was used during surgery, or to treat toothaches. It was also put into drinks. When Coca-Cola was first made in 1885, it got the first part of its name from the "handful of coca leaves" added to the drink for energy. (The caffeine in the drink came from the kola nut, so the name "Coca-Cola" was chosen.) Cocaine was taken out of Coca-Cola completely by the 1920s because of pressure from groups in the United States.