Antioch
After Alexander's death in 323 BC, his generals divided up the territory he had conquered. Seleucus I Nicator won the territory of Syria, and he founded four "sister cities" in north-western Syria - Antioch, Seleucia Pieria, Apamea and Laodicea-on-the-Sea. Although Seleucia Pieria was at first the Seleucid capital city in north-western Syria, Antioch soon rose above it to become the Syrian capital.