Quantum mechanics
One example is Young's double-slit experiment. If we shoot single photons (single units of light) from a laser at a sheet of photographic film, we will see a single spot of light on the developed film. If we put a sheet of metal in between, and make two very narrow slits in the sheet, when we fire many photons at the metal sheet, and they have to go through the slits, then we will see something remarkable. All the way across the sheet of developed film we will see a series of bright and dark bands. We can use mathematics to tell exactly where the bright bands will be and how bright the light was that made them, that is, we can tell ahead of time how many photons will fall on each band. But if we slow the process down and see where each photon lands on the screen we can never tell ahead of time where the next one will show up. We can know for sure that it is most likely that a photon will hit the center bright band, and that it gets less and less likely that a photon will show up at bands farther and farther from the center. So we know for sure that the bands will be brightest at the center and get dimmer and dimmer farther away. But we never know for sure which photon will go into which band.