Exposure (toxicology)
Also, once a toxin gets into the bloodstream, the body immediately starts trying to get rid of it through excretion.  The main organs involved with excretion are the kidneys, liver, and lungs.  If a person has damage to any of these organs (like kidney failure or cirrhosis of the liver), they will be unable to get rid of the toxin as fast as a healthy person will.  The chemical will stay in their body longer, and have more toxic effects.p. 103