Coronary artery disease
Atherosclerosis is a form of heart disease. It causes fatty materials (like cholesterol) to build up in the arteries, forming harder materials called plaques. This causes the arteries to become narrower. It also makes it more difficult for blood to flow through the arteries. This can cause blood clots to form, blocking blood from traveling through the arteries.  Small pieces of plaque can also break off and block smaller blood vessels.