Edna Krabappel
Edna's first husband cheated on her. She told Nelzon Muntz about it by saying he "chased something small and fluffy down the rabbit hole". This is a metaphor for having an affair. In the episode "Flaming Moe's", she tries to seduce Joey Kramer and Homer Simpson. The episode "Bart the Lover" has Bart pretending to be a man that loves Edna.