known, the category “unknown substance” should be used.
The name of the disorder is followed by the sp ecification of onset (i.e., onset during in-
toxication, onset during withdrawal, with onse t after medication use), followed by the se-
verity specifier (e.g., mild, moderate, severe ). Unlike the recording procedures for ICD-10-
CM, which combine the substance-induced disord er and substance use disorder into a sin-
gle code, for ICD-9-CM a separate diagnostic code is given for the su bstance use disorder.
For example, in the case of erectile dysfun ction occurring during intoxication in a man
with a severe alcohol use diso rder, the diagnosis is 291.89 al cohol-induced sexual dysfunc-
tion, with onset during intoxication, modera te. An additional diagnosis of 303.90 severe
alcohol use disorder is also given. When more  than one substance is judged to play a sig-ICD-10-CM
ICD-9-CMWith use 
disorder, 
mildWith use 
disorder, 
moderate 
or severeWithout 
use 
disorder
Alcohol 291.89 F10.181 F10.281 F10.981
Opioid 292.89 F11.181 F11.281 F11.981
Sedative, hypnotic, or 
anxiolytic292.89 F13.181 F13.281 F13.981
Amphetamine (or other 
stimulant)292.89 F15.181 F15.281 F15.981
Cocaine 292.89 F14.181 F14.281 F14.981
Other (or unknown) substance 292.89 F19.181 F19.281 F19.981