with onset during intoxication ) because the symptoms in thes e latter disorders predominate
the clinical presentation and are severe enou gh to warrant independent clinical attention.
Other substance intoxication. Alcohol intoxication and seda tive, hypnotic, or anxiolytic
intoxication can cause a clinical picture that resembles that for opioid intoxication. A diag-
nosis of alcohol or sedative, hypnotic, or anxiol ytic intoxication can usually be made based
on the absence of pupillary constriction or the lack of a response to naloxone challenge. In