iety, problems with appetite or sleeping, or difficulties with concentration. After several
weeks, these symptoms may be followed by incoordination, altered vision, or abnormal
gait or other movements that may be myoclonic,  choreoathetoid, or ballistic, along with a
rapidly progressive dementia. The disease typi cally progresses very rapidly to the major
level of impairment over several months. More rarely, it can progress over 2 years and ap-
pear similar in its course to other NCDs.