Depressive Disorder Due to Another Medical Condition 181
Specify if: 
(F06.31) With depressive features: Full criteria are not met for a major depressive
episode.
(F06.32) With major depressive–like episode:  Full criteria are met (except Criterion
C) for a major depressive episode.
(F06.34) With mixed features: Symptoms of mania or hypomania are also present but
do not predominate in the clinical picture.
Coding note:  Include the name of the other medical condition in the name of the mental dis-
order (e.g., 293.83 [F06.31] depressive disorder due to hypothyroidism, with depressive fea-
tures). The other medical condition should al so be coded and listed separately immediately
before the depressive disorder due to the medical condition (e.g., 244.9 [E03.9] hypothyroid-
ism; 293.83 [F06.31] depressive disorder due to hypothyroidism, with depressive features).
Diagnostic Features
The essential feature of depressive disorder  due to another medical condition is a promi-
nent and persistent period of depressed mood or markedly diminished interest or plea-
sure in all, or almost all, ac tivities that predominates in th e clinical picture (Criterion A)
and that is thought to be related to the direct  physiological effects of another medical con-
dition (Criterion B). In determining whethe r the mood disturbance is due to a general
medical condition, the clinician must first establish the presence of a general medical con-
dition. Further, the clinician mu st establish that the mood di sturbance is etiologically re-
lated to the general medical condition through a physiological mechanism. A careful and
comprehensive assessment of multiple factor s is necessary to make this judgment. Al-