118 Schizophrenia Spectrum and Other Psychotic Disorders
Suicide Risk 
Suicide risk in the context of psychotic diso rder due to another me dical condition is not
clearly delineated, although certain conditions  such as epilepsy and multiple sclerosis are
associated with increased rates of suicide, which may be further increased in the presence
of psychosis. 
Functional Consequences of Psychotic Disorder 
Due to Another Medical Condition
Functional disability is typically severe in the context of psychotic di sorder due to another
medical condition but will vary  considerably by the type of condition and likely improve
with successful resolution of the condition.
Differential Diagnosis
Delirium. Hallucinations and delusions commonly occur in the context of a delirium;
however, a separate diagnosis of psychotic disorder due to another medical condition is
not given if the disturbance occurs exclusively during the co urse of a delirium. Delusions
in the context of a major or mild neurocogni tive disorder would be diagnosed as major or
mild neurocognitive disorder, with behavioral disturbance. 
Substance/medication-induced psychotic disorder. If there is evidence of recent or
prolonged substance use (including medicati ons with psychoactive effects), withdrawal
from a substance, or exposure to a toxin (e.g ., LSD [lysergic acid diethylamide] intoxica-
tion, alcohol withdrawal), a substance/medica tion-induced psychotic disorder should be
considered. Symptoms that occur during or shor tly after (i.e., within 4 weeks) of substance
intoxication or withdrawal or after medication use may be es pecially indicative of a sub-
stance-induced psychotic disorder, depending on the character, duration, or amount of
the substance used. If the clin ician has ascertained that the disturbance is due to both a